Hedgehog Signaling

Content: 
Copyright
Page iv

Former Editors
Page v

Contributors
Pages xv-xix

Preface
Pages xxi-xxii

Chapter One - Hedgehog Signaling
Pages 1-23
Siu Wah Choy, Shuk Han Cheng

Chapter two - Canonical and Noncanonical Hedgehog/GLI Signaling in Hematological Malignancies
Pages 25-54
Fritz Aberger, Daniela Kern, Richard Greil, Tanja Nicole Hartmann

Chapter three - Noncanonical Hedgehog Signaling
Pages 55-72
Donna Brennan, Xiaole Chen, Lan Cheng, My Mahoney, Natalia A. Riobo

Chapter four - Gli Protein Nuclear Localization Signal
Pages 73-89
Minoru Hatayama, Jun Aruga

Chapter five - Mammalian Homologues of Drosophila Fused Kinase
Pages 91-113
Alla Maloverjan, Marko Piirsoo

Chapter six - Identification, Functional Characterization, and Pathobiological Significance of GLI1 Isoforms in Human Cancers
Pages 115-140
Richard L. Carpenter, Hui-Wen Lo

Chapter seven - Gli-Similar Proteins: Their Mechanisms of Action, Physiological Functions, and Roles in Disease
Pages 141-171
Kristin Lichti-Kaiser, Gary ZeRuth, Hong Soon Kang, Shivakumar Vasanth, Anton M. Jetten

Chapter eight - Sonic Hedgehog Regulates Wnt Activity During Neural Circuit Formation
Pages 173-209
Nicole H. Wilson, Esther T. Stoeckli

Chapter nine - Hedgehog/Gli Control by Ubiquitination/Acetylation Interplay
Pages 211-227
Alberto Gulino, Lucia Di Marcotullio, Gianluca Canettieri, Enrico De Smaele, Isabella Screpanti

Chapter ten - Palmitoylation of Hedgehog Proteins
Pages 229-252
John A. Buglino, Marilyn D. Resh

Chapter eleven - Phosphorylation Regulation of Hedgehog Signaling
Pages 253-272
Jianhang Jia

Chapter twelve - Protein Kinase A Activity and Hedgehog Signaling Pathway
Pages 273-291
Tomoya Kotani

Chapter thirteen - Phosphorylation of Gli by cAMP-Dependent Protein Kinase
Pages 293-307
Yoshinari Asaoka

Chapter fourteen - ZFP932 Suppresses Cellular Hedgehog Response and Patched1 Transcription
Pages 309-332
G. Jason Huang, Zhenhua He, Liang Ma

Chapter fifteen - A New Era for an Ancient Drug: Arsenic Trioxide and Hedgehog Signaling
Pages 333-354
Elspeth M. Beauchamp, Aykut Üren

Chapter sixteen - Aberrations and Therapeutics Involving the Developmental Pathway Hedgehog in Pancreatic cancer
Pages 355-378
Fergal C. Kelleher, Raymond McDermott

Chapter seventeen - Sonic Hedgehog Signaling and Potential Therapeutic Indications
Pages 379-394
Nicholas C. Bambakidis, Kaine Onwuzulike

Chapter eighteen - Sonic Hedgehog on Microparticles and Neovascularization
Pages 395-438
Raffaella Soleti, Maria Carmen Martinez

Chapter nineteen - “Patch”-ing up the Neurons: Revival or Enervation?
Pages 439-459
Sayantani Ghosh, Arunabha Chakrabarti, Debashis Mukhopadhyay

Chapter twenty - Activation of Hedgehog Pathway in Gastrointestinal Cancers
Pages 461-472
Ling Yang, Xiulan Su, Jingwu Xie

Chapter twenty-one - The Role of Sonic Hedgehog as a Regulator of Gastric Function and Differentiation
Pages 473-489
Rui Feng, Chang Xiao, Yana Zavros

Chapter twenty-two - Sonic Hedgehog-Mediated Synergistic Effects Guiding Angiogenesis and Osteogenesis
Pages 491-506
Sabine Fuchs, Eva Dohle, Charles James Kirkpatrick

Chapter twenty-three - Hedgehog Inhibition as an Anti-Cancer Strategy
Pages 507-522
G. Praveen Raju, Diane Pham

Index
Pages 523-534