Heart Function and Metabolism: Proceedings of the Symposium held at the Eighth Annual Meeting of the American Section of the International Society for Heart Research, July 8–11, 1986, Winnipeg, Canada

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Molecular Biology and Cardiac Function, Past, Present and Future....Pages 3-21
Front Matter....Pages 23-23
Regulation of Calcium Slow Channels and Potassium Channels of Cardiac Muscle by Cyclic Nucleotides and Metabolism....Pages 25-65
Potassium Channels Identified with Single Channel Recordings and Their Role in Cardiac Excitation....Pages 67-78
Na and Ca Channels in the Heart....Pages 79-92
Sodium Pathways In and Out of the Cardiac Cells: Relationship to Inotropy....Pages 93-102
Nondriven Electrical Activity in Cardiac Ventricular Fibers....Pages 103-115
Regulation of Cl - Activity in Ventricular Muscle: Cl - /HCO - 3 Exchange and Na + -dependent Cl - Cotransport....Pages 117-131
Front Matter....Pages 133-133
Parasympathetic Control of the Heart: Subcellular Mechanisms....Pages 135-161
Role of Phosphatidylethanolaminb N-Methylation on Ca 2+ Transport in Cardiac Membranes....Pages 163-175
Na + -Ca 2+ Exchange in Cardiac Sarcolemmal Vesicles....Pages 177-180
NA/K Pump Function in Cultured Embryonic Chick Heart Cells....Pages 181-190
Characteristics of Ca 2+ /Mg 2+ Atpase in Heart Sarcolemma Treated with Trypsin....Pages 191-203
Front Matter....Pages 205-205
Depression of Canine Ventricular Sarcoplasmic Reticulum by the Calcium Channel Agonist, Bay K 8644....Pages 207-220
Biophysical Aspects of Ca 2+ - Transport Sites in Skeletal and Cardiac Sarcoplasmic Reticulum (Ca 2+ + Mg 2+ )-ATPase....Pages 221-241
Mechanisms of Sarcoplasmic Reticulum Functions and Consequences for Muscle Activity....Pages 243-253
Protein Phosphorylation in Cardiac Sarcoplasmic Reticulum and Its Functional Consequences....Pages 255-266
The Ca 2+ ATPase of Cardiac Muscle Sarcoplasmic Reticulum....Pages 267-276
Front Matter....Pages 277-277
Contractile and Regulatory Proteins in Cardiovascular System....Pages 279-291
Distribution of Cardiac Myosin Isozymes in Human and Rat Heart-Immunohistochemical Study Using Monoclonal Antibodies....Pages 293-305
Remodelling of the Myocyte at a Molecular Level — Relationship Between Myosin Isoenzyme Population and Sarcoplasmic Reticulum....Pages 307-318
Front Matter....Pages 277-277
Isomyosins and Isoactins in Mammalian Myocardium....Pages 319-328
Crossbridge Mechanisms of Contraction in Vascular Smooth Muscle....Pages 329-351
Front Matter....Pages 353-353
Control of Glucose Uptake and Utilization in the Myocardium....Pages 355-369
Blockade of Sugar Transport Decreases Contractility of Aortic Smooth Muscle....Pages 371-376
Control of Energy Transport in Cardiac Muscle....Pages 377-395
Creatine Kinase and Mechanical Properties of Rat Ventricular Muscle....Pages 397-406
Hemodynamic Performance of Creatine-Depleted Rat Heart in Isolated Blood-Perfused Working Preparation....Pages 407-425
Localization of Glucose-6-Phosphatase (G-6-Pase) in the Rat Heart Muscle Cells....Pages 427-432