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دانلود کتاب Harrison's Principles of Internal Medicine

دانلود کتاب اصول طب داخلی هریسون

Harrison's Principles of Internal Medicine

مشخصات کتاب

Harrison's Principles of Internal Medicine

ویرایش: [21 ed.] 
نویسندگان: ,   
سری:  
ISBN (شابک) : 1264268513, 9781264268511 
ناشر: McGraw-Hill Education 
سال نشر: 2022 
تعداد صفحات: 4132 
زبان: English 
فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود) 
حجم فایل: 220 Mb 

قیمت کتاب (تومان) : 49,000



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توضیحاتی در مورد کتاب اصول طب داخلی هریسون

The Voice of Clinical Reason اصول طب داخلی هریسون معتبرترین متن پزشکی بالینی در جهان است - و منبعی عالی برای یادگیری هنر و علم استدلال بالینی. اصول طب داخلی هریسون که توسط متخصصان مراقبت های بهداشتی در سراسر جهان به عنوان مرجع پیشرو در پاتوفیزیولوژی کاربردی و پزشکی بالینی شناخته شده است، پایه اطلاعاتی مورد نیاز شما را برای بهترین مراقبت از بیمار فراهم می کند. این نسخه جدید به طور کامل با فصل های جدید به موقع و به روز رسانی های ضروری در سراسر طیف پزشکی داخلی به روز شده است. اصول طب داخلی هریسون به عنوان معیاری برای اطلاعات معتبر و عملی در مورد مراقبت از بیمار و پاتوژنز و مدیریت بالینی علائم و نشانه ها و بیماری های خاص است. این راهنمای برجسته که توسط متخصصان برتر جهان در زمینه های مربوطه خود نوشته و ویرایش شده است، پوشش جامع، دقیق و ضروری از پاتوژنز، تشخیص و درمان بیماری را ارائه می دهد. هریسون به عنوان معتبرترین منبع در جهان شهرت دارد: • توصیف مکانیسم های بیماری و اینکه چگونه پزشک می تواند آن دانش را برای بهترین مراقبت از بیمار و تشخیص و درمان بهینه بیماری های خاص به کار گیرد • طرحواره های واضح و مختصر که تولید تشخیص های افتراقی را تسهیل می کند. استدلال کارآمد از طریق موارد پیچیده بالینی در دنیای واقعی • مبنای فیزیولوژیک و اپیدمیولوژیک علائم و نشانه ها، که از طریق انبوهی از راهنمایی های متخصص بی نظیر پوشش داده شده و به فصل های خاص بیماری مرتبط می شود • نتایج کارآزمایی بالینی به روز و دستورالعمل های توصیه شده • عالی و پشتیبانی بصری گسترده، از جمله رادیوگرافی، عکس‌های بالینی، شماتیک‌ها و نقاشی‌های با کیفیت بالا • پوشش هر دو رویکرد درمانی و رژیم‌های درمانی خاص • درختان و الگوریتم‌های تصمیم‌گیری بالینی عملی • بخش‌های خاص ارگان، با پاتوفیزیولوژی مرتبط بالینی و توصیه‌های بالینی عملی در مورد رویکرد به بیمار، استراتژی‌هایی برای ایجاد تشخیص افتراقی، الگوریتم‌های بالینی برجسته و طرح‌واره‌های تشخیصی، انبوهی از تصاویر و نمودارهای بالینی، دستورالعمل‌های بالینی فعلی، رویکردهای عمومی و خاص برای درمان، هریسون قابل اعتمادترین منبع در دنیایی است که تحت تأثیر بی‌پایان است. منابع اطلاعات پزشکی به‌موقع‌ترین و جامع‌ترین به‌روزرسانی‌های متخصصان برتر جهان در نسخه بیست و یکم ارائه شده است: • پوشش فعلی تشخیص و درمان بیماری‌ها، از کووید گرفته تا زوال عقل، سپسیس، مولتیپل اسکلروزیس و سرطان ریه • محتوای به‌روز شده که منعکس‌کننده درمان‌های تأیید شده جدید و دستورالعمل‌ها و خلاصه‌های شواهد جدید تغییر عملکرد • بیش از 1000 عکس بالینی، پاتولوژیک، و رادیوگرافی، درخت تصمیم تشخیصی و درمانی، و شماتیک‌ها و نمودارهای واضحی که فرآیندهای پاتوفیزیولوژیک را توصیف می‌کنند • بیش از دوازده اطلس دارای مجموعه‌ای از جنبه‌های بصری تشخیص و مدیریت • درمان کامل و به روز شده و ترکیب ادبیات اولیه پزشکی که شامل داده های فعلی از مطالعات عمده و کارآزمایی های بالینی است.


توضیحاتی درمورد کتاب به خارجی

The Voice of Clinical ReasonHarrison’s Principles of Internal Medicine is the world's most trusted clinical medicine text—and a superb resource for learning the art and science of clinical reasoning. Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine provides the informational foundation you need for the best patient care possible. This new edition is fully updated with timely new chapters and essential updates across the spectrum of internal medicine. Harrison's Principles of Internal Medicine stands as the benchmark for authoritative, practical information on patient care and the pathogenesis and clinical management of symptoms and signs and specific diseases. Written and edited by the world’s top experts in their respective fields, this landmark guide provides the comprehensive, accurate, and essential coverage of the pathogenesis, diagnosis, and treatment of disease. Harrison’s is world-renowned as the most authoritative source for: • Descriptions of disease mechanisms and how the clinician can apply that knowledge for the best patient care and optimal diagnosis and treatment of specific diseases • Clear, concise schemas that facilitate the generation of differential diagnoses to reason efficiently through complex real world clinical cases • The physiologic and epidemiologic basis of signs and symptoms, which are covered through a wealth of unsurpassed expert guidance and linked to the disease-specific chapters that follow • Updated clinical trial results and recommended guidelines • Excellent and extensive visual support, including radiographs, clinical photos, schematics, and high-quality drawings • Coverage of both therapeutic approaches and specific treatment regimens • Practical clinical decision trees and algorithms • Organ-specific sections, with clinically relevant pathophysiology and practical clinical advice on the approach to the patient, strategies towards building a differential diagnosis, outstanding clinical algorithms and diagnostic schema, a wealth of clinical images and diagrams, current clinical guidelines, general and specific approaches to therapy Harrison’s remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world’s top experts are featured in the 21st edition: • Current coverage of the diagnosis and treatment of diseases, from COVID to dementia to sepsis to multiple sclerosis to lung cancer • Updated content that reflects new approved therapeutics and new practice-changing guidelines and evidence summaries • More than 1000 clinical, pathological, and radiographic photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams describing pathophysiologic processes • More than a dozen atlases featuring curated collections of visual aspects of diagnosis and management • Complete, updated curation and synthesis of primary medical literature which incorporates current data from major studies and clinical trials • Clinical reasoning resources and helpful disease/presentation schemas • Clinically relevant coverage of disease mechanics and pathophysiology, and related therapeutic mechanisms



فهرست مطالب

Cover
Title Page
Copyright Page
Contents
Contributors
Preface
Harrison’s Related Resources
PART 1 The Profession of Medicine
	1 The Practice of Medicine
	2 Promoting Good Health
	3 Vaccine Opposition and Hesitancy
	4 Decision-Making in Clinical Medicine
	5 Precision Medicine and Clinical Care
	6 Screening and Prevention of Disease
	7 Global Diversity of Health System Financing and Delivery
	8 The Safety and Quality of Health Care
	9 Diagnosis: Reducing Errors and Improving Quality
	10 Racial and Ethnic Disparities in Health Care
	11 Ethical Issues in Clinical Medicine
	12 Palliative and End-of-Life Care
PART 2 Cardinal Manifestations and Presentation of Diseases
	SECTION 1 Pain
		13 Pain: Pathophysiology and Management
		14 Chest Discomfort
		15 Abdominal Pain
		16 Headache
		17 Back and Neck Pain
	SECTION 2 Alterations in Body Temperature
		18 Fever
		19 Fever and Rash
		20 Fever of Unknown Origin
	SECTION 3 Nervous System Dysfunction
		21 Syncope
		22 Dizziness and Vertigo
		23 Fatigue
		24 Neurologic Causes of Weakness and Paralysis
		25 Numbness, Tingling, and Sensory Loss
		26 Gait Disorders, Imbalance, and Falls
		27 Confusion and Delirium
		28 Coma
		29 Dementia
		30 Aphasia, Memory Loss, and Other Cognitive Disorders
		31 Sleep Disorders
	SECTION 4 Disorders of Eyes, Ears, Nose, and Throat
		32 Disorders of the Eye
		33 Disorders of Smell and Taste
		34 Disorders of Hearing
		35 Upper Respiratory Symptoms, Including Earache, Sinus Symptoms, and Sore Throat
		36 Oral Manifestations of Disease
	SECTION 5 Alterations in Circulatory and Respiratory Functions
		37 Dyspnea
		38 Cough
		39 Hemoptysis
		40 Hypoxia and Cyanosis
		41 Edema
		42 Approach to the Patient with a Heart Murmur
		43 Palpitations
	SECTION 6 Alterations in Gastrointestinal Function
		44 Dysphagia
		45 Nausea, Vomiting, and Indigestion
		46 Diarrhea and Constipation
		47 Unintentional Weight Loss
		48 Gastrointestinal Bleeding
		49 Jaundice
		50 Abdominal Swelling and Ascites
	SECTION 7 Alterations in Renal and Urinary Tract Function
		51 Interstitial Cystitis/Bladder Pain Syndrome
		52 Azotemia and Urinary Abnormalities
		53 Fluid and Electrolyte Disturbances
		54 Hypercalcemia and Hypocalcemia
		55 Acidosis and Alkalosis
	SECTION 8 Alterations in the Skin
		56 Approach to the Patient with a Skin Disorder
		57 Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders
		58 Skin Manifestations of Internal Disease
		59 Immunologically Mediated Skin Diseases
		60 Cutaneous Drug Reactions
		61 Photosensitivity and Other Reactions to Sunlight
	SECTION 9 Hematologic Alterations
		62 Interpreting Peripheral Blood Smears
		63 Anemia and Polycythemia
		64 Disorders of Granulocytes and Monocytes
		65 Bleeding and Thrombosis
		66 Enlargement of Lymph Nodes and Spleen
PART 3 Pharmacology
	67 Principles of Clinical Pharmacology
	68 Pharmacogenomics
PART 4 Oncology and Hematology
	SECTION 1 Neoplastic Disorders
		69 Approach to the Patient with Cancer
		70 Prevention and Early Detection of Cancer
		71 Cancer Genetics
		72 Cancer Cell Biology
		73 Principles of Cancer Treatment
		74 Infections in Patients with Cancer
		75 Oncologic Emergencies
		76 Cancer of the Skin
		77 Head and Neck Cancer
		78 Neoplasms of the Lung
		79 Breast Cancer
		80 Upper Gastrointestinal Tract Cancers
		81 Lower Gastrointestinal Cancers
		82 Tumors of the Liver and Biliary Tree
		83 Pancreatic Cancer
		84 Gastrointestinal Neuroendocrine Tumors
		85 Renal Cell Carcinoma
		86 Cancer of the Bladder and Urinary Tract
		87 Benign and Malignant Diseases of the Prostate
		88 Testicular Cancer
		89 Gynecologic Malignancies
		90 Primary and Metastatic Tumors of the Nervous System
		91 Soft Tissue and Bone Sarcomas and Bone Metastases
		92 Carcinoma of Unknown Primary
		93 Paraneoplastic Syndromes: Endocrinologic/Hematologic
		94 Paraneoplastic Neurologic Syndromes and Autoimmune Encephalitis
		95 Cancer Survivorship and the Long-Term Impact of Cancer and Its Treatment
	SECTION 2 Hematopoietic Disorders
		96 Hematopoietic Stem Cells
		97 Iron Deficiency and Other Hypoproliferative Anemias
		98 Disorders of Hemoglobin
		99 Megaloblastic Anemias
		100 Hemolytic Anemias
		101 Anemia Due to Acute Blood Loss
		102 Bone Marrow Failure Syndromes Including Aplastic Anemia and Myelodysplasia
		103 Polycythemia Vera and Other Myeloproliferative Neoplasms
		104 Acute Myeloid Leukemia
		105 Chronic Myeloid Leukemia
		106 Acute Lymphoid Leukemia
		107 Chronic Lymphocytic Leukemia
		108 Non-Hodgkin’s Lymphoma
		109 Hodgkin’s Lymphoma
		110 Less Common Lymphoid and Myeloid Malignancies
		111 Plasma Cell Disorders
		112 Amyloidosis
		113 Transfusion Therapy and Biology
		114 Hematopoietic Cell Transplantation
	SECTION 3 Disorders of Hemostasis
		115 Disorders of Platelets and Vessel Wall
		116 Coagulation Disorders
		117 Arterial and Venous Thrombosis
		118 Antiplatelet, Anticoagulant, and Fibrinolytic Drugs
PART 5 Infectious Diseases
	SECTION 1 Basic Considerations in Infectious Diseases
		119 Approach to the Patient with an Infectious Disease
		120 Molecular Mechanisms of Microbial Pathogenesis
		121 Microbial Genomics and Infectious Disease
		122 Approach to the Acutely Ill Infected Febrile Patient
		123 Immunization Principles and Vaccine Use
		124 Health Recommendations for International Travel
		125 Climate Change and Infectious Disease
	SECTION 2 Clinical Syndromes: Community-Acquired Infections
		126 Pneumonia
		127 Lung Abscess
		128 Infective Endocarditis
		129 Infections of the Skin, Muscles, and Soft Tissues
		130 Infectious Arthritis
		131 Osteomyelitis
		132 Intraabdominal Infections and Abscesses
		133 Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning
		134 Clostridioides difficile Infection, Including Pseudomembranous Colitis
		135 Urinary Tract Infections, Pyelonephritis, and Prostatitis
		136 Sexually Transmitted Infections: Overview and Clinical Approach
		137 Encephalitis
		138 Acute Meningitis
		139 Chronic and Recurrent Meningitis
		140 Brain Abscess and Empyema
		141 Infectious Complications of Bites
	SECTION 3 Clinical Syndromes: Health Care–Associated Infections
		142 Infections Acquired in Health Care Facilities
		143 Infections in Transplant Recipients
	SECTION 4 Therapy for Bacterial Diseases
		144 Treatment and Prophylaxis of Bacterial Infections
		145 Bacterial Resistance to Antimicrobial Agents
	SECTION 5 Diseases Caused by Gram-Positive Bacteria
		146 Pneumococcal Infections
		147 Staphylococcal Infections
		148 Streptococcal Infections
		149 Enterococcal Infections
		150 Diphtheria and Other Corynebacterial Infections
		151 Listeria monocytogenes Infections
		152 Tetanus
		153 Botulism
		154 Gas Gangrene and Other Clostridial Infections
	SECTION 6 Diseases Caused by Gram-Negative Bacteria
		155 Meningococcal Infections
		156 Gonococcal Infections
		157 Haemophilus and Moraxella Infections
		158 Infections Due to the HACEK Group and Miscellaneous Gram-Negative Bacteria
		159 Legionella Infections
		160 Pertussis and Other Bordetella Infections
		161 Diseases Caused by Gram-Negative Enteric Bacilli
		162 Acinetobacter Infections
		163 Helicobacter pylori Infections
		164 Infections Due to Pseudomonas, Burkholderia, and Stenotrophomonas Species
		165 Salmonellosis
		166 Shigellosis
		167 Infections Due to Campylobacter and Related Organisms
		168 Cholera and Other Vibrioses
		169 Brucellosis
		170 Tularemia
		171 Plague and Other Yersinia Infections
		172 Bartonella Infections, Including Cat-Scratch Disease
		173 Donovanosis
	SECTION 7 Miscellaneous Bacterial Infections
		174 Nocardiosis
		175 Actinomycosis
		176 Whipple’s Disease
		177 Infections Due to Mixed Anaerobic Organisms
	SECTION 8 Mycobacterial Diseases
		178 Tuberculosis
		179 Leprosy
		180 Nontuberculous Mycobacterial Infections
		181 Antimycobacterial Agents
	SECTION 9 Spirochetal Diseases
		182 Syphilis
		183 Endemic Treponematoses
		184 Leptospirosis
		185 Relapsing Fever and Borrelia miyamotoi Disease
		186 Lyme Borreliosis
	SECTION 10 Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae
		187 Rickettsial Diseases
		188 Infections Due to Mycoplasmas
		189 Chlamydial Infections
	SECTION 11 Viral Diseases: General Considerations
		190 Principles of Medical Virology
		191 Antiviral Chemotherapy, Excluding Antiretroviral Drugs
	SECTION 12 Infections Due to DNA Viruses
		192 Herpes Simplex Virus Infections
		193 Varicella-Zoster Virus Infections
		194 Epstein-Barr Virus Infections, Including Infectious Mononucleosis
		195 Cytomegalovirus and Human Herpesvirus Types 6, 7, and 8
		196 Molluscum Contagiosum, Monkeypox, and Other Poxvirus Infections
		197 Parvovirus Infections
		198 Human Papillomavirus Infections
	SECTION 13 Infections Due to DNA and RNA Respiratory Viruses
		199 Common Viral Respiratory Infections, Including COVID-19
		200 Influenza
	SECTION 14 Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses
		201 The Human Retroviruses
		202 Human Immunodeficiency Virus Disease: AIDS and Related Disorders
	SECTION 15 Infections Due to RNA Viruses
		203 Viral Gastroenteritis
		204 Enterovirus, Parechovirus, and Reovirus Infections
		205 Measles (Rubeola)
		206 Rubella (German Measles)
		207 Mumps
		208 Rabies and Other Rhabdovirus Infections
		209 Arthropod-Borne and Rodent-Borne Virus Infections
		210 Ebolavirus and Marburgvirus Infections
	SECTION 16 Fungal Infections
		211 Pathogenesis, Diagnosis, and Treatment of Fungal Infections
		212 Histoplasmosis
		213 Coccidioidomycosis
		214 Blastomycosis
		215 Cryptococcosis
		216 Candidiasis
		217 Aspergillosis
		218 Mucormycosis
		219 Less Common Systemic Mycoses and Superficial Mycoses
		220 Pneumocystis Infections
	SECTION 17 Protozoal and Helminthic Infections: General Considerations
		221 Introduction to Parasitic Infections
		222 Agents Used to Treat Parasitic Infections
	SECTION 18 Protozoal Infections
		223 Amebiasis and Infection with Free-Living Amebae
		224 Malaria
		225 Babesiosis
		226 Leishmaniasis
		227 Chagas Disease and African Trypanosomiasis
		228 Toxoplasma Infections
		229 Protozoal Intestinal Infections and Trichomoniasis
	SECTION 19 Helminthic Infections
		230 Introduction to Helminthic Infections
		231 Trichinellosis and Other Tissue Nematode Infections
		232 Intestinal Nematode Infections
		233 Filarial and Related Infections
		234 Schistosomiasis and Other Trematode Infections
		235 Cestode Infections
PART 6 Disorders of the Cardiovascular System
	SECTION 1 Introduction to Cardiovascular Disorders
		236 Approach to the Patient with Possible Cardiovascular Disease
		237 Basic Biology of the Cardiovascular System
		238 Epidemiology of Cardiovascular Disease
	SECTION 2 Diagnosis of Cardiovascular Disorders
		239 Physical Examination of the Cardiovascular System
		240 Electrocardiography
		241 Noninvasive Cardiac Imaging: Echocardiography, Nuclear Cardiology, and Magnetic Resonance/Computed Tomography Imaging
		242 Diagnostic Cardiac Catheterization and Coronary Angiography
	SECTION 3 Disorders of Rhythm
		243 Principles of Clinical Cardiac Electrophysiology
		244 The Bradyarrhythmias: Disorders of the Sinoatrial Node
		245 The Bradyarrhythmias: Disorders of the Atrioventricular Node
		246 Approach to Supraventricular Tachyarrhythmias
		247 Physiologic and Nonphysiologic Sinus Tachycardia
		248 Focal Atrial Tachycardia
		249 Paroxysmal Supraventricular Tachycardias
		250 Common Atrial Flutter and Macroreentrant and Multifocal Atrial Tachycardias
		251 Atrial Fibrillation
		252 Approach to Ventricular Arrhythmias
		253 Premature Ventricular Contractions, Nonsustained Ventricular Tachycardia, and Accelerated Idioventricular Rhythm
		254 Sustained Ventricular Tachycardia
		255 Polymorphic Ventricular Tachycardia and Ventricular Fibrillation
		256 Electrical Storm and Incessant Ventricular Tachycardia
	SECTION 4 Disorders of the Heart, Muscles, Valves, and Pericardium
		257 Heart Failure: Pathophysiology and Diagnosis
		258 Heart Failure: Management
		259 Cardiomyopathy and Myocarditis
		260 Cardiac Transplantation and Prolonged Assisted Circulation
		261 Aortic Stenosis
		262 Aortic Regurgitation
		263 Mitral Stenosis
		264 Mitral Regurgitation
		265 Mitral Valve Prolapse
		266 Tricuspid Valve Disease
		267 Pulmonic Valve Disease
		268 Multiple and Mixed Valvular Heart Disease
		269 Congenital Heart Disease in the Adult
		270 Pericardial Disease
		271 Atrial Myxoma and Other Cardiac Tumors
		272 Cardiac Trauma
	SECTION 5 Coronary and Peripheral Vascular Disease
		273 Ischemic Heart Disease
		274 Non-ST-Segment Elevation Acute Coronary Syndrome (Non-ST-Segment Elevation Myocardial Infarction and Unstable Angina)
		275 ST-Segment Elevation Myocardial Infarction
		276 Percutaneous Coronary Interventions and Other Interventional Procedures
		277 Hypertension
		278 Renovascular Disease
		279 Deep-Venous Thrombosis and Pulmonary Thromboembolism
		280 Diseases of the Aorta
		281 Arterial Diseases of the Extremities
		282 Chronic Venous Disease and Lymphedema
		283 Pulmonary Hypertension
PART 7 Disorders of the Respiratory System
	SECTION 1 Diagnosis of Respiratory Disorders
		284 Approach to the Patient with Disease of the Respiratory System
		285 Disturbances of Respiratory Function
		286 Diagnostic Procedures in Respiratory Disease
	SECTION 2 Diseases of the Respiratory System
		287 Asthma
		288 Hypersensitivity Pneumonitis and Pulmonary Infiltrates with Eosinophilia
		289 Occupational and Environmental Lung Disease
		290 Bronchiectasis
		291 Cystic Fibrosis
		292 Chronic Obstructive Pulmonary Disease
		293 Interstitial Lung Disease
		294 Disorders of the Pleura
		295 Disorders of the Mediastinum
		296 Disorders of Ventilation
		297 Sleep Apnea
		298 Lung Transplantation
		299 Interventional Pulmonary Medicine
PART 8 Critical Care Medicine
	SECTION 1 Respiratory Critical Care
		300 Approach to the Patient with Critical Illness
		301 Acute Respiratory Distress Syndrome
		302 Mechanical Ventilatory Support
	SECTION 2 Shock and Cardiac Arrest
		303 Approach to the Patient with Shock
		304 Sepsis and Septic Shock
		305 Cardiogenic Shock and Pulmonary Edema
		306 Cardiovascular Collapse, Cardiac Arrest, and Sudden Cardiac Death
	SECTION 3 Neurologic Critical Care
		307 Nervous System Disorders in Critical Care
PART 9 Disorders of the Kidney and Urinary Tract
	308 Approach to the Patient with Renal Disease or Urinary Tract Disease
	309 Cell Biology and Physiology of the Kidney
	310 Acute Kidney Injury
	311 Chronic Kidney Disease
	312 Dialysis in the Treatment of Kidney Failure
	313 Transplantation in the Treatment of Renal Failure
	314 Glomerular Diseases
	315 Polycystic Kidney Disease and Other Inherited Disorders of Tubule Growth and Development
	316 Tubulointerstitial Diseases of the Kidney
	317 Vascular Injury to the Kidney
	318 Nephrolithiasis
	319 Urinary Tract Obstruction
	320 Interventional Nephrology
PART 10 Disorders of the Gastrointestinal System
	SECTION 1 Disorders of the Alimentary Tract
		321 Approach to the Patient with Gastrointestinal Disease
		322 Gastrointestinal Endoscopy
		323 Diseases of the Esophagus
		324 Peptic Ulcer Disease and Related Disorders
		325 Disorders of Absorption
		326 Inflammatory Bowel Disease
		327 Irritable Bowel Syndrome
		328 Diverticular Disease and Common Anorectal Disorders
		329 Mesenteric Vascular Insufficiency
		330 Acute Intestinal Obstruction
		331 Acute Appendicitis and Peritonitis
	SECTION 2 Nutrition
		332 Nutrient Requirements and Dietary Assessment
		333 Vitamin and Trace Mineral Deficiency and Excess
		334 Malnutrition and Nutritional Assessment
		335 Enteral and Parenteral Nutrition
	SECTION 3 Liver and Biliary Tract Disease
		336 Approach to the Patient with Liver Disease
		337 Evaluation of Liver Function
		338 The Hyperbilirubinemias
		339 Acute Viral Hepatitis
		340 Toxic and Drug-Induced Hepatitis
		341 Chronic Hepatitis
		342 Alcohol-Associated Liver Disease
		343 Nonalcoholic Fatty Liver Diseases and Nonalcoholic Steatohepatitis
		344 Cirrhosis and Its Complications
		345 Liver Transplantation
		346 Diseases of the Gallbladder and Bile Ducts
	SECTION 4 Disorders of the Pancreas
		347 Approach to the Patient with Pancreatic Disease
		348 Acute and Chronic Pancreatitis
PART 11 Immune-Mediated, Inflammatory, and Rheumatologic Disorders
	SECTION 1 The Immune System in Health and Disease
		349 Introduction to the Immune System
		350 Mechanisms of Regulation and Dysregulation of the Immune System
		351 Primary Immune Deficiency Diseases
	SECTION 2 Disorders of Immune-Mediated Injury
		352 Urticaria, Angioedema, and Allergic Rhinitis
		353 Anaphylaxis
		354 Mastocytosis
		355 Autoimmunity and Autoimmune Diseases
		356 Systemic Lupus Erythematosus
		357 Antiphospholipid Syndrome
		358 Rheumatoid Arthritis
		359 Acute Rheumatic Fever
		360 Systemic Sclerosis (Scleroderma) and Related Disorders
		361 Sjögren’s Syndrome
		362 Spondyloarthritis
		363 The Vasculitis Syndromes
		364 Behçet Syndrome
		365 Inflammatory Myopathies
		366 Relapsing Polychondritis
		367 Sarcoidosis
		368 IgG4-Related Disease
		369 Familial Mediterranean Fever and Other Hereditary Autoinflammatory Diseases
	SECTION 3 Disorders of the Joints and Adjacent Tissues
		370 Approach to Articular and Musculoskeletal Disorders
		371 Osteoarthritis
		372 Gout and Other Crystal-Associated Arthropathies
		373 Fibromyalgia
		374 Arthritis Associated with Systemic Disease, and Other Arthritides
		375 Periarticular Disorders of the Extremities
PART 12 Endocrinology and Metabolism
	SECTION 1 Endocrinology
		376 Approach to the Patient with Endocrine Disorders
		377 Mechanisms of Hormone Action
		378 Physiology of Anterior Pituitary Hormones
		379 Hypopituitarism
		380 Pituitary Tumor Syndromes
		381 Disorders of the Neurohypophysis
		382 Thyroid Gland Physiology and Testing
		383 Hypothyroidism
		384 Hyperthyroidism and Other Causes of Thyrotoxicosis
		385 Thyroid Nodular Disease and Thyroid Cancer
		386 Disorders of the Adrenal Cortex
		387 Pheochromocytoma
		388 Multiple Endocrine Neoplasia Syndromes
		389 Autoimmune Polyendocrine Syndromes
	SECTION 2 Sex- and Gender-Based Medicine
		390 Sex Development
		391 Disorders of the Testes and Male Reproductive System
		392 Disorders of the Female Reproductive System
		393 Menstrual Disorders and Pelvic Pain
		394 Hirsutism
		395 Menopause and Postmenopausal Hormone Therapy
		396 Infertility and Contraception
		397 Sexual Dysfunction
		398 Women’s Health
		399 Men’s Health
		400 Lesbian, Gay, Bisexual, and Transgender (LGBT) Health
	SECTION 3 Obesity, Diabetes Mellitus, and Metabolic Syndrome
		401 Pathobiology of Obesity
		402 Evaluation and Management of Obesity
		403 Diabetes Mellitus: Diagnosis, Classification, and Pathophysiology
		404 Diabetes Mellitus: Management and Therapies
		405 Diabetes Mellitus: Complications
		406 Hypoglycemia
		407 Disorders of Lipoprotein Metabolism
		408 The Metabolic Syndrome
	SECTION 4 Disorders of Bone and Mineral Metabolism
		409 Bone and Mineral Metabolism in Health and Disease
		410 Disorders of the Parathyroid Gland and Calcium Homeostasis
		411 Osteoporosis
		412 Paget’s Disease and Other Dysplasias of Bone
	SECTION 5 Disorders of Intermediary Metabolism
		413 Heritable Disorders of Connective Tissue
		414 Hemochromatosis
		415 Wilson’s Disease
		416 The Porphyrias
		417 Disorders of Purine and Pyrimidine Metabolism
		418 Lysosomal Storage Diseases
		419 Glycogen Storage Diseases and Other Inherited Disorders of Carbohydrate Metabolism
		420 Inherited Disorders of Amino Acid Metabolism in Adults
		421 Inherited Defects of Membrane Transport
PART 13 Neurologic Disorders
	SECTION 1 Diagnosis of Neurologic Disorders
		422 Approach to the Patient with Neurologic Disease
		423 Neuroimaging in Neurologic Disorders
		424 Pathobiology of Neurologic Diseases
	SECTION 2 Diseases of the Central Nervous System
		425 Seizures and Epilepsy
		426 Introduction to Cerebrovascular Diseases
		427 Ischemic Stroke
		428 Intracranial Hemorrhage
		429 Subarachnoid Hemorrhage
		430 Migraine and Other Primary Headache Disorders
		431 Alzheimer’s Disease
		432 Frontotemporal Dementia
		433 Vascular Dementia
		434 Dementia with Lewy Bodies
		435 Parkinson’s Disease
		436 Tremor, Chorea, and Other Movement Disorders
		437 Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases
		438 Prion Diseases
		439 Ataxic Disorders
		440 Disorders of the Autonomic Nervous System
		441 Trigeminal Neuralgia, Bell’s Palsy, and Other Cranial Nerve Disorders
		442 Diseases of the Spinal Cord
		443 Concussion and Other Traumatic Brain Injuries
		444 Multiple Sclerosis
		445 Neuromyelitis Optica
	SECTION 3 Nerve and Muscle Disorders
		446 Peripheral Neuropathy
		447 Guillain-Barré Syndrome and Other Immune-Mediated Neuropathies
		448 Myasthenia Gravis and Other Diseases of the Neuromuscular Junction
		449 Muscular Dystrophies and Other Muscle Diseases
	SECTION 4 Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
		450 Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
	SECTION 5 Psychiatric and Addiction Disorders
		451 Biology of Psychiatric Disorders
		452 Psychiatric Disorders
		453 Alcohol and Alcohol Use Disorders
		454 Nicotine Addiction
		455 Marijuana and Marijuana Use Disorders
		456 Opioid-Related Disorders
		457 Cocaine, Other Psychostimulants, and Hallucinogens
PART 14 Poisoning, Drug Overdose, and Envenomation
	458 Heavy Metal Poisoning
	459 Poisoning and Drug Overdose
	460 Disorders Caused by Venomous Snakebites and Marine Animal Exposures
	461 Ectoparasite Infestations and Arthropod Injuries
PART 15 Disorders Associated with Environmental Exposures
	462 Altitude Illness
	463 Hyperbaric and Diving Medicine
	464 Hypothermia and Peripheral Cold Injuries
	465 Heat-Related Illnesses
PART 16 Genes, the Environment, and Disease
	466 Principles of Human Genetics
	467 The Practice of Genetics in Clinical Medicine
	468 Mitochondrial DNA and Heritable Traits and Diseases
	469 Telomere Disease
	470 Gene- and Cell-Based Therapy in Clinical Medicine
	471 The Human Microbiome
PART 17 Global Medicine
	472 Global Issues in Medicine
	473 Emerging and Reemerging Infectious Diseases
	474 Primary Care and Global Health
	475 Health Effects of Climate Change
PART 18 Aging
	476 Biology of Aging
	477 Caring for the Geriatric Patient
PART 19 Consultative Medicine
	478 Approach to Medical Consultation
	479 Medical Disorders During Pregnancy
	480 Medical Evaluation of the Surgical Patient
PART 20 Frontiers
	481 Behavioral Economics and Health
	482 Complementary and Integrative Therapies and Practices
	483 The Role of Epigenetics in Disease and Treatment
	484 Applications of Stem Cell Biology in Clinical Medicine
	485 The Role of Circadian Biology in Health and Disease
	486 Network Medicine: Systems Biology in Health and Disease
	487 Emerging Neurotherapeutic Technologies
	488 Machine Learning and Augmented Intelligence in Clinical Medicine
	489 Metabolomics
	490 Circulating Nucleic Acids as Liquid Biopsies and Noninvasive Disease Biomarkers
	491 Protein Folding Disorders
	492 Novel Approaches to Diseases of Unknown Etiology
Index




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