Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques

Contents......Page 8
Foreword......Page 12
Editor......Page 14
Contributors......Page 16
Part I Fundamentals and Methodologies......Page 24
Introduction to Capillary Electrophoresis......Page 26
Protein Analysis by Capillary Electrophoresis......Page 98
Micellar Electrokinetic Chromatography......Page 132
Capillary Electrophoresis for Pharmaceutical Analysis......Page 158
Principles and Practice of Capillary Electrochromatography......Page 206
Capillary Electrophoresis of Nucleic Acids......Page 250
Analysis of Carbohydrates by Capillary Electrophoresis......Page 274
The Coupling of Capillary Electrophoresis and Mass Spectrometry in Proteomics......Page 318
Light-Based Detection Methods for Capillary Electrophoresis......Page 328
Microfluidic Devices for Electrophoretic Separations: Fabrication and Use......Page 358
Part IIA Capillary-Based Systems: CoreMethods and Technologies......Page 382
Kinetic Capillary Electrophoresis......Page 384
DNA Sequencing and Genotyping by Free-Solution Conjugate Electrophoresis......Page 404
Online Sample Preconcentration for Capillary Electrophoresis......Page 436
Capillary Electrophoresis for the Analysis of Single Cells: Sampling, Detection, and Applications......Page 452
Ultrafast Electrophoretic Separations......Page 468
DNA Sequencing by Capillary Electrophoresis......Page 490
Dynamic Computer Simulation Software for Capillary Electrophoresis......Page 538
Heat Production and Dissipation in Capillary Electrophoresis......Page 568
Isoelectric Focusing in Capillary Systems......Page 586
Part IIB Capillary-Based Systems: SpecializedMethods and Technologies......Page 604
Subcellular Analysis by Capillary Electrophoresis......Page 606
Chemical Cytometry: Capillary Electrophoresis Analysis at the Level of the Single Cell......Page 634
Glycoprotein Analysis by Capillary Electrophoresis......Page 654
Capillary Electrophoresis of Post-Translationally Modi.ed Proteins and Peptides......Page 730
Extreme Resolution in Capillary Electrophoresis: UHVCE, FCCE, and SCCE......Page 746
Separation of DNA for Forensic Applications Using Capillary Electrophoresis......Page 784
Clinical Application of CE......Page 808
Solid-Phase Microextraction and Solid Phase Extraction with Capillary Electrophoresis and Related Techniques......Page 834
CE-SELEX: Isolating Aptamers Using Capillary Electrophoresis......Page 848
Microfluidic Technology as a Platform to Investigate Microcirculation......Page 864
Capillary Electrophoresis Applications for Food Analysis......Page 876
Separation Strategies for Environmental Analysis......Page 936
Part IIIA Microchip-Based: Core Methods andTechnologies......Page 1002
Cell Manipulation at the Micron Scale......Page 1004
Multidimensional Micro.uidic Systems for Protein and Peptide Separations......Page 1024
Microchip Immunoassays......Page 1036
Solvent Extraction on Chips......Page 1044
Electrophoretic Microdevices for Clinical Diagnostics......Page 1060
Advances in Micro.uidics: Development of a Forensic Integrated DNA Microchip (IDChip)......Page 1088
Taylor Dispersion in Sample Preconcentration Methods......Page 1108
The Mechanical Behavior of Films and Interfaces in Micro.uidic Devices: Implications for Performance and Reliability......Page 1144
Practical Fluid Control Strategies for Micro.uidic Devices......Page 1176
Low-Cost Technologies for Micro.uidic Applications......Page 1192
Microfluidic Reactors for Small Molecule and Nanomaterial Synthesis......Page 1208
Part IIIB Microchip-Based: SpecializedMethods and Technologies......Page 1228
Sample Processing with Integrated Micro.uidic Systems......Page 1230
Cell and Particle Separation and Manipulation Using Acoustic Standing Waves in Micro.uidic Systems......Page 1252
Optical Detection Systems for Microchips......Page 1276
Microfabricated Electrophoresis Devices for High-Throughput Genetic Analysis: Milestones and Challenges......Page 1300
Macroporous Monoliths for Chromatographic Separations in Microchannels......Page 1320
Microdialysis and Microchip Systems......Page 1350
Microfluidic Sample Preparation for Proteomics Analysis Using MALDI-MS......Page 1364
Implementing Sample Preconcentration in Micro.uidic Devices......Page 1398
Using Phase-Changing Sacri.cial Materials to Fabricate Microdevices for Chemical Analysis......Page 1442
Materials and Modi.cation Strategies for Electrophoresis Microchips......Page 1464
Microfluidic Devices with Mass Spectrometry Detection......Page 1482
Nanoscale Self-Assembly of Stationary Phases for Capillary Electrophoresis of DNA......Page 1530
Nanoscale DNA Analysis......Page 1550
Index......Page 1566