Goldman-Cecil Medicine (2-Volume Set)

Volume 1
	Cover
	GOLDMAN-CECIL MEDICINE
	GOLDMAN-CECIL MEDICINE
	ASSOCIATE EDITORS
	Copyright
	PREFACE
	CONTRIBUTORS
	CONTENTS
	VIDEO CONTENTS
	SECTION 1: SOCIAL AND ETHICAL ISSUES IN MEDICINE
		1 - Approach to Medicine, the patient, and the medical profession
		2 - BIOETHICS IN THE PRACTICE OF MEDICINE
		3 - PALLIATIVE CARE
		4 - DISPARITIES IN HEALTH ANDHEALTH CARE
		5 - GLOBAL HEALTH
	SECTION 2: PRINCIPLES OF EVALUATION AND MANAGEMENT
		6 - HISTORY AND PHYSICAL EXAMINATION
		7 - APPROACH TO THE PATIENT WITH ABNORMAL VITAL SIGNS
		8 - STATISTICAL INTERPRETATION OF DATA FOR CLINICAL DECISION MAKING
		9 - MEASURING HEALTH AND HEALTH CARE
		10 - QUALITY, SAFETY, AND VALUE
		11 - POPULATION HEALTH
	SECTION 3: PREVENTIVE AND ENVIRONMENTAL ISSUES
		12 - THE PREVENTIVE HEALTH VISIT
		13 - DIET AND NUTRITION
		14 - PHYSICAL ACTIVITY
		15 - IMMUNIZATION
		16 - PRINCIPLES OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
		17 - EFFECTS OF CLIMATE CHANGE ON HEALTH
		18 - RADIATION INJURY
		19 - BIOTERRORISM
		20 - CHRONIC POISONING: TRACE METALS AND OTHERS
	SECTION 4: AGING AND GERIATRIC MEDICINE
		21 - Adolescent Medicine
		22 - EPIDEMIOLOGY OF AGING
		23 - GERIATRIC ASSESSMENT
		24 - COMMON CLINICAL SEQUELAE OF AGING
	SECTION 5: CLINICAL PHARMACOLOGY
		25 - PRINCIPLES OF DRUG THERAPY
		26 -  PAIN
		27 - BIOLOGY OF ADDICTION
		28 - IMMUNOMODULATORY DRUGS
		29 - BIOLOGIC AGENTS AND SIGNALING INHIBITORS
		30 - COMPLEMENTARY AND INTEGRATIVE MEDICINE
	SECTION 6: GENETICS
		31 - PRINCIPLES OF GENETICS
		32 - CLINICAL GENOMICS—GENOME STRUCTURE AND VARIATION
		33 - APPLICATIONS OF MOLECULAR TECHNOLOGIES TO CLINICAL MEDICINE
		34 - REGENERATIVE MEDICINE, CELL THERAPY, AND GENE THERAPY
	SECTION 7: PRINCIPLES OF IMMUNOLOGY AND INFLAMMATION
		35 - THE INNATE AND ADAPTIVE IMMUNE SYSTEMS
		36 - TISSUE INJURY AND REPAIR
		37 - COMPLEMENT SYSTEM IN DISEASE
		38 - TRANSPLANTATION IMMUNOLOGY
	SECTION 8: HEART DISEASE
		39 - APPROACH TO THE PATIENT WITH POSSIBLE CARDIOVASCULAR DISEASE
		40 - EPIDEMIOLOGY OF CARDIOVASCULAR DISEASE
		41 - CARDIAC AND CIRCULATORY FUNCTION
		42 - ELECTROCARDIOGRAPHY
		43 - ECHOCARDIOGRAPHY
		44 - NONINVASIVE CARDIAC IMAGING
		45 - HEART FAILURE: EPIDEMIOLOGY, PATHOBIOLOGY, AND DIAGNOSIS
		46 - HEART FAILURE: TREATMENT AND PROGNOSIS
		47 - DISEASES OF THE MYOCARDIUM AND ENDOCARDIUM
		48 - PRINCIPLES OF ELECTROPHYSIOLOGY
		49 - APPROACH TO THE PATIENT WITH SUSPECTED ARRHYTHMIA
		50 - CARDIAC ARREST AND LIFE-THREATENING ARRHYTHMIAS
		51 - BRADYCARDIAS AND CONDUCTION SYSTEM DELAYS
		52 - SUPRAVENTRICULAR ECTOPY AND TACHYARRHYTHMIAS
		53 - VENTRICULAR ARRHYTHMIAS
		54 - ELECTROPHYSIOLOGIC PROCEDURES AND SURGERY
		55 - CONGENITAL HEART DISEASE IN ADULTS
		56 - ANGINA PECTORIS AND CHRONIC ISCHEMIC HEART DISEASE
		57 - ACUTE CORONARY SYNDROME: UNSTABLE ANGINA AND NON–ST ELEVATION MYOCARDIAL INFARCTION
		58 - ST-ELEVATION ACUTE MYOCARDIAL INFARCTION AND COMPLICATIONS OF MYOCARDIAL INFARCTION
		59 - INTERVENTIONAL DIAGNOSIS AND TREATMENT OF CORONARY ARTERY DISEASE
		60 - VALVULAR HEART DISEASE
		61 - INFECTIVE ENDOCARDITIS
		62 - PERICARDIAL DISEASES
	SECTION 9: VASCULAR MEDICINE
		63 - DISEASES OF THE AORTA
		64 - ARTERIAL HYPERTENSION
		65 - ATHEROSCLEROTIC PERIPHERAL ARTERIAL DISEASE
		66 - OTHER PERIPHERAL ARTERIAL DISEASES
		67 - THROMBOTIC DISORDERS: HYPERCOAGULABLE STATES
		68 - VENOUS THROMBOSIS AND EMBOLISM
		69 - PULMONARY HYPERTENSION
		70 - ANTITHROMBOTIC AND ANTIPLATELET THERAPY
	SECTION 10: RESPIRATORY DISEASES
		71 - APPROACH TO THE PATIENT WITH RESPIRATORY DISEASE
		72 - IMAGING IN PULMONARY DISEASE
		73 - RESPIRATORY TESTING AND FUNCTION
		74 - DISORDERS OF VENTILATORY CONTROL
		75 - ASTHMA
		76 - CHRONIC OBSTRUCTIVE PULMONARY DISEASE
		77 - CYSTIC FIBROSIS
		78 - BRONCHIECTASIS, ATELECTASIS, AND CAVITARY OR CYSTIC LUNG DISEASES
		79 - ALVEOLAR FILLING DISORDERS
		80 - INTERSTITIAL LUNG DISEASE
		81 - OCCUPATIONAL LUNG DISEASE
		82 - PHYSICAL AND CHEMICAL INJURIESOF THE LUNG
		83 - SARCOIDOSIS
		84 - ACUTE BRONCHITIS AND TRACHEITIS
		85 - OVERVIEW OF PNEUMONIA
		86 - DISEASES OF THE DIAPHRAGM, CHEST WALL, PLEURA, AND MEDIASTINUM
		87 - INTERVENTIONAL AND SURGICAL APPROACHES TO LUNG DISEASE
	SECTION 11: CRITICAL CARE MEDICINE
		88 - APPROACH TO THE PATIENT IN A CRITICAL CARE SETTING
		89 - RESPIRATORY MONITORING IN CRITICAL CARE
		90 - ACUTE RESPIRATORY FAILURE
		91 - MECHANICAL VENTILATION
		92 - APPROACH TO THE PATIENTWITH SHOCK
		93 - CARDIOGENIC SHOCK
		94 - SHOCK SYNDROMES RELATED TO SEPSIS
		95 - DISORDERS DUE TO HEAT AND COLD
		96 - ACUTE POISONING
		97 - MEDICAL ASPECTS OF TRAUMAAND BURNS
		98 - ENVENOMATION, BITES, AND STINGS
		99 - RHABDOMYOLYSIS
	SECTION 12: RENAL AND GENITOURINARY DISEASES
		100 - APPROACH TO THE PATIENT WITH RENAL DISEASE
			DIAGNOSIS
				Measuring Kidney Function
					FIGURE 100-1. Overview of approach to kidney disease. Quantitative defects in filtration, manifested by elevated serum creatinine (Scr) and reduced glomerular filtration rate(GFR), should lead to a query into acute kidney injury (AKI) versus chronic kidney disease (CKD). AKI, in turn, is generally divided into prerenal, postrenal, and intrinsic causes. Qualitativedefects in filtration, manifested by proteinuria or hematuria, can occur in the absence of changes in GFR and often require biopsy for diagnosis. Proteinuria of more than 3.5 g/day signalsnephrotic syndrome, which may be idiopathic or secondary to systemic diseases, such as hepatitis B or C, human immunodeficiency virus (HIV) infection, or diabetes. Glomerular hematuriawithout AKI is consistent with a chronic glomerulopathy, such as IgA nephropathy, or familial diseases, such as thin basement membranes disease. When hematuria accompaniesAKI, acute glomerulonephritis should be suspected and can diagnostically be divided into low-complement glomerulonephritides (immune complex–mediated lesions such as lupusnephritis, postinfectious glomerulonephritis, and cryoglobulinemic glomerulonephritis) and normocomplementemic glomerulonephritides (classically seen in the rapidly progressiveglomerulonephropathies due to antineutrophil cytoplasmic antibody [ANCA] and anti–glomerular basement membrane [anti-GBM] antibody). ANA = antinuclear antibody; ASLO =antistreptolysin O; BUN = blood urea nitrogen; Cr = creatinine; CT = computed tomography; MCD = minimal change disease; FeNa = fractional excretion of sodium; FSGS = focal segmentalglomerulosclerosis; MN = membranous nephropathy; SFLC = serum free light chain; SIEP = serum immunoelectrophoresis; US, ultrasonography.
					CONSIDERATIONS FOR INTERPRETATION OFGFR VALUESTABLE
				Approach to Diagnosis
				FIGURE 100-2. Relationship between plasma creatinine and glomerular filtrationrate measured by inulin clearance in 171 patients (circles). The continuous line reflectsthe idealized relationship between these parameters if creatinine were excreted solelyby glomerular filtration; the dashed line represents an upper limit of “normal” for thecreatinine concentration of 1.4 mg/dL.
				Urinalysis
					TABLE 100-2 MACROSCOPIC APPEARANCE OF URINE
					Urine Dipstick
					Urine Sediment
						Hematuria
							FIGURE 100-3. Algorithm for the evaluation of asymptomatic hematuria. BPH = benign prostatic hyperplasia; CT = computed tomography; GFR = glomerular filtration rate; MRI= magnetic resonance imaging; RBC = red blood cell; UTI = urinary tract infection.
							FIGURE 100-4. Dysmorphic erythrocytes. These dysmorphic erythrocytes vary insize, shape, and hemoglobin content and reflect glomerular bleeding.
							FIGURE 100-5. Isomorphic erythrocytes. These erythrocytes are similar in size, shape,and hemoglobin content. Isomorphic cells reflect nonglomerular bleeding from lesionssuch as calculi and papillomas or hemorrhage from cysts in polycystic renal disease.
						Pyuria
							TABLE 100-3 CAUSES OF STERILE PYURIA
						Casts and Crystals
							FIGURE 100-6. Hyaline cast of the type seen in small numbers in normal urine.
							FIGURE 100-7. Number and type of granules and their density in the cast vary indifferent casts. The presence of erythrocytes in this cast may mean that the granules arederived partly from disrupted erythrocytes.
							FIGURE 100-8. A cast composed entirely of erythrocytes reflects heavy hematuriaand active glomerular disease. Crescentic nephritis is likely to be present if erythrocytecast density is greater than 100/mL.
							FIGURE 100-9. Typical hexagonal cystine crystal. A single crystal provides a definitivediagnosis of cystinuria.
							FIGURE 100-10. Oxalate crystals. A pseudocast of calcium oxalate crystals accompaniedby crystals of calcium oxalate dehydrate.
							FIGURE 100-11. Coffin lid crystals of magnesium ammonium phosphate (struvite).
							FIGURE 100-12. Urate crystals. Complex crystals suggestive of acute urate nephropathyor urate nephrolithiasis.
						Other Elements
				Disorders of Electrolytes
					FIGURE 100-13. Regulation of potassium balance. ACE = angiotensin-converting enzyme; AKI = acute kidney injury; GI = gastrointestinal.
			SPECIFIC RENAL SYNDROMES
				ACUTE KIDNEY INJURY
					DIAGNOSIS
						Laboratory Testing
						Imaging
							FIGURE 100-14. Normal findings on sagittal renal ultrasound. The cortex is hypoechoiccompared with the echogenic fat containing the renal sinus.
							FIGURE 100-15. Delayed excretion in the left kidney secondary to a distal calculus.Contrast-enhanced computed tomography scan shows dilated left renal pelvis.
				GLOMERULAR SYNDROMES: NEPHROTICVERSUS NEPHRITIC
					DIAGNOSIS
						Laboratory Testing
							Serologies
						Renal Biopsy
						Genetic Testing
							E-FIGURE 100-1. Diagnoses in individuals with kidney disease of unknown etiology. A review of six genome-wide studies identified 47 distinct genetic etiologies correspondingwith the categories listed within the inner disc. The genes identified are represented in the outer ring, with the number of patients affected in parentheses. CAKUT = congenital anomaliesof the kidneys and urinary tract.
				TUBULOINTERSTITIAL DISEASES
				VASCULITIS AND VASCULAR DISEASES OF THEKIDNEY
					DIAGNOSIS
						Radiologic Evaluation
							FIGURE 100-16. Magnetic resonance angiography. Coronal three-dimensional imageshows right renal artery stenosis (arrow).
				PAPILLARY NECROSIS
		101 - STRUCTURE AND FUNCTIONOF THE KIDNEYS
		102 - DISORDERS OF SODIUM AND WATER
		103 - POTASSIUM DISORDERS
		104 - ACID-BASE DISORDERS
		105 - DISORDERS OF MAGNESIUM AND PHOSPHORUS
		106 - ACUTE KIDNEY INJURY
		107 - GLOMERULAR DISORDERS AND NEPHROTIC SYNDROMES
		108 - INTERSTITIAL NEPHRITIS
		109 - DIABETES AND THE KIDNEY
		110 - VASCULAR DISORDERS OF THE KIDNEY
		111 - NEPHROLITHIASIS
		112 - CYSTIC KIDNEY DISEASES
		113 - HEREDITARY NEPHROPATHIES ANDDEVELOPMENTAL RENAL/URINARYABNORMALITIES
		114 - BENIGN PROSTATIC HYPERLASIA AND PROSTATITIS
		115 - URINARY INCONTINENCE
		116 - CHRONIC KIDNEY DISEASE
		117 - TREATMENT OF IRREVERSIBLE RENAL FAILURE
	SECTION 13: GASTROINTESTINAL DISEASES
		118 - APPROACH TO THE PATIENT WITH GASTROINTESTINAL DISEASE
		119 - DIAGNOSTIC IMAGING PROCEDURESIN GASTROENTEROLOGY
		120 - GASTROINTESTINAL ENDOSCOPY
		121 - GASTROINTESTINAL HEMORRHAGE
		122 - DISORDERS OF GASTROINTESTINAL MOTILITY
		123 - IRRITABLE BOWEL AND FUNCTIONAL UPPER GASTROINTESTINAL SYNDROMES
		124 - DISEASES OF THE ESOPHAGUS
		125 - ACID PEPTIC DISEASE
		126 - APPROACH TO THE PATIENT WITH DIARRHEA AND MALABSORPTION
		127 - INFLAMMATORY BOWEL DISEASE
		128 - INFLAMMATORY AND ANATOMIC DISEASES OF THE INTESTINE, PERITONEUM, MESENTERY, AND OMENTUM
		129 - VASCULAR DISEASES OF THE GASTROINTESTINAL TRACT
		130 - PANCREATITIS
		131 - DISEASES OF THE RECTUM AND ANUS
	SECTION 14: DISEASES OF THE LIVER AND BILIARY SYSTEM
		132 - APPROACH TO THE PATIENT WITHLIVER DISEASE
		133 - APPROACH TO THE PATIENT WITH JAUNDICE OR ABNORMAL LIVER TESTS
		134 - ACUTE VIRAL HEPATITIS
		135 - CHRONIC VIRAL AND AUTOIMMUNE HEPATITIS
		136 - DRUG-INDUCED LIVER INJURY
		137 - BACTERIAL, PARASITIC, FUNGAL, AND GRANULOMATOUS LIVER DISEASES
		138 - ALCOHOLIC AND NONALCOHOLIC STEATOHEPATITIS
		139 - CIRRHOSIS AND ITS SEQUELAE
		140 - LIVER FAILURE AND TRANSPLANTATION
		141 - DISEASES OF THE GALLBLADDER AND BILE DUCTS
	SECTION 15: HEMATOLOGIC DISEASES
		142 - HEMATOPOIESIS AND HEMATOPOIETIC GROWTH FACTORS
		143 - THE PERIPHERAL BLOOD SMEAR
		144 - APPROACH TO THE ANEMIAS
		145 - MICROCYTIC AND HYPOCHROMIC ANEMIAS
		146 - AUTOIMMUNE AND INTRAVASCULAR HEMOLYTIC ANEMIAS
		147 - 0HEMOLYTIC ANEMIAS: RED BLOOD CELLL MEMBRANE AND METABOLIC DEFECTS
		148 - THE THALASSEMIAS
		149 - SICKLE CELL DISEASE AND OTHER HEMOGLOBINOPATHIES
		150 - MEGALOBLASTIC ANEMIAS
		151 - APLASTIC ANEMIA AND RELATED BONE MARROW FAILURE STATES
		152 - POLYCYTHEMIA VERA, ESSENTIAL THROMBOCYTHEMIA, AND PRIMARY MYELOFIBROSIS
		153 - LEUKOCYTOSIS AND LEUKOPENIA
		154 - APPROACH TO THE PATIENT WITH LYMPHADENOPATHY OR SPLENOMEGALY
		155 - HISTIOCYTOSES
		156 - EOSINOPHILIC SYNDROMES
		157 - APPROACH TO THE PATIENT WITH BLEEDING OR THROMBOSIS
		158 - THROMBOCYTOPENIA
		159 - VON WILLEBRAND DISEASE AND HEMORRHAGIC ABNORMALITIES OF PLATELET AND VASCULAR FUNCTION
		160 - COAGULATION FACTOR DEFICIENCIES
		161 - DISSEMINATED INTRAVASCULAR COAGULATION AND BLEEDING IN LIVER FAILURE
		162 - TRANSFUSION MEDICINE
		163 - HEMATOPOIETIC CELL TRANSPLANTATION
	SECTION 16: ONCOLOGY
		164 - APPROACH TO THE PATIENT WITH CANCER
		165 - EPIDEMIOLOGY OF CANCER
		166 - CANCER BIOLOGY AND GENETICS
		167 - MYELODYSPLASTIC SYNDROMES
		168 - THE ACUTE LEUKEMIAS
		169 - CHRONIC LYMPHOCYTIC LEUKEMIA
		170 - CHRONIC MYELOID LEUKEMIA
		171 - NON-HODGKIN LYMPHOMAS
		172 - HODGKIN LYMPHOMA
		173 - PLASMA CELL DISORDERS
		174 - AMYLOIDOSIS
		175 - TUMORS OF THE CENTRAL NERVOUS SYSTEM
		176 - HEAD AND NECK CANCER
		177 - LUNG CANCER AND OTHER PULMONARY NEOPLASMS
		178 -NEOPLASMS OF THE ESOPHAGUS AND STOMACH
		179 - NEOPLASMS OF THE SMALL AND LARGE INTESTINE
		180 - PANCREATIC CANCER
		181 - LIVER AND BILIARY TRACT TUMORS
		182 - TUMORS OF THE KIDNEY, BLADDER, URETERS, AND RENAL PELVIS
		183 - BREAST CANCER AND BENIGN BREAST DISORDERS
		184 - GYNECOLOGIC CANCERS
		185 - TESTICULAR CANCER
		186 - PROSTATE CANCER
		187 - MALIGNANT BONE TUMORS, SARCOMAS, AND OTHER SOFT TISSUE NEOPLASMS
		188 - MELANOMA AND NONMELANOMASKIN CANCERS
Volume 2
	SECTION 17: METABOLIC DISEASES
		189 - APPROACH TO INBORN ERRORSOF METABOLISM
		190 - DISORDERS OF LIPID METABOLISM
		191 - GLYCOGEN STORAGE DISEASES
		192 - LYSOSOMAL STORAGE DISEASES
		193 - HOMOCYSTINURIA AND HYPERHOMOCYSTEINEMIA
		194 - THE PORPHYRIAS
		195 - WILSON DISEASE
		196 - IRON OVERLOAD (HEMOCHROMATOSIS)
	SECTION 18: NUTRITIONAL DISEASES
		197 - SEVERE MALNUTRITION
		198 - MALNUTRITION: ASSESSMENT AND SUPPORT
		199 - VITAMINS, TRACE MINERALS, AND OTHER MICRONUTRIENTS
		200- EATING DISORDERS
		201 - OBESITY
	SECTION 19: ENDOCRINE DISEASES
		202 - APPROACH TO THE PATIENT WITH ENDOCRINE DISEASE
		203 - PRINCIPLES OF ENDOCRINOLOGY
		204 - NEUROENDOCRINOLOGY AND THE NEUROENDOCRINE SYSTEM
		205 - ANTERIOR PITUITARY
		206 - POSTERIOR PITUITARY
		207 - THYROID
		208 - ADRENAL CORTEX
		209 -ADRENAL MEDULLA, CATECHOLAMINES, AND PHEOCHROMOCYTOMA
		210 - DIABETES MELLITUS
		211 - HYPOGLYCEMIA
		212 - POLYGLANDULAR DISORDERS
		213 - NEUROENDOCRINE NEOPLASMS
		214 - SEXUAL DEVELOPMENT
		215 - TRANSGENDER MEDICINE
		216 - THE TESTIS AND MALE HYPOGONADISM, INFERTILITY, AND SEXUAL DYSFUNCTION
		217 - OVARIES AND PUBERTAL DEVELOPMENT
		218 - REPRODUCTIVE ENDOCRINOLOGY AND INFERTILITY
	SECTION 20: WOMEN\'S HEALTH
		219 - APPROACH TO WOMEN’S HEALTH
		220 - CONTRACEPTION
		221 - MEDICAL ISSUES IN PREGNANCY
		222 - MENOPAUSE
		223 - INTIMATE PARTNER VIOLENCE
	SECTION 21: DISEASES OF BONE AND MINERAL METABOLISM
		224 - APPROACH TO THE PATIENT WITH METABOLIC BONE DISEASE
		225 - OSTEOPOROSIS
		226 - OSTEOMALACIA AND RICKETS
		227 - THE PARATHYROID GLANDS, HYPERCALCEMIA, AND HYPOCALCEMIA
		228 - PAGET DISEASE OF BONE
		229 - OSTEONECROSIS, OSTEOSCLEROSIS/HYPEROSTOSIS, AND OTHERDISORDERS OF BONE
	SECTION 22: DISEASES OF ALLERGY AND CLINICAL IMMUNOLOGY
		230 - APPROACH TO THE PATIENT WITH ALLERGIC OR IMMUNOLOGIC DISEASE
		231 - PRIMARY IMMUNODEFICIENCY DISEASES
		232 - URTICARIA AND ANGIOEDEMA
		233 - ANAPHYLAXIS
		234 - DRUG ALLERGY
		235 - MASTOCYTOSIS
	SECTION 23: RHEUMATIC DISEASES
		236 - APPROACH TO THE PATIENT WITH RHEUMATIC DISEASE
		237 - LABORATORY TESTING IN THE RHEUMATIC DISEASES
		238 - IMAGING STUDIES IN THE RHEUMATIC DISEASESR
		239 - INHERITED DISEASES OF CONNECTIVE TISSUE
		240 - THE SYSTEMIC AUTOINFLAMMATORY DISEASES
		241 - OSTEOARTHRITIS
		242 - BURSITIS, TENDINOPATHY, OTHER PERIARTICULAR DISORDERS, AND SPORTS MEDICINE
		243 - RHEUMATOID ARTHRITIS
		244 - SPONDYLOARTHRITIS
		245 - SYSTEMIC LUPUS ERYTHEMATOSUS
		246 - SYSTEMIC SCLEROSIS (SCLERODERMA)
		247 - SJÖGREN SYNDROME
		248- INFLAMMATORY MYOPATHIES
		249 - THE SYSTEMIC VASCULITIDES
		250 - GIANT CELL ARTERITIS AND POLYMYALGIA RHEUMATICA
		251 - INFECTIONS OF BURSAE, JOINTS,AND BONES
		252 - CRYSTAL DEPOSITION DISEASES
		253 - FIBROMYALGIA
		254 - SYSTEMIC DISEASES IN WHICH ARTHRITIS IS A FEATURE
		255- SURGICAL TREATMENT OF JOINT DISEASES
	SECTION 24: INFECTIOUS DISEASES
		256 -
INTRODUCTION TO MICROBIAL DISEASE: PATHOPHYSIOLOGY AND DIAGNOSTICS
		257 -
THE HUMAN MICROBIOME
		258 -
PRINCIPLES OF ANTI-INFECTIVE THERAPY
		259 - APPROACH TO FEVER OR SUSPECTED INFECTION IN THE NORMAL HOST
		260 -
APPROACH TO FEVER AND SUSPECTED INFECTION IN THE IMMUNOCOMPROMISED HOST
		261 - PREVENTION AND CONTROL OF HEALTH CARE–ASSOCIATED INFECTIONS
		262 -
APPROACH TO THE PATIENT WITH SUSPECTED ENTERIC INFECTION
		263 -
APPROACH TO THE PATIENT WITH URINARY TRACT INFECTION
		264 -
APPROACH TO THE PATIENT WITH A SEXUALLY TRANSMITTED INFECTION
		265 - APPROACH TO THE PATIENT BEFORE AND AFTER TRAVEL
		266 -
ANTIBACTERIAL CHEMOTHERAPY
		267 -
STAPHYLOCOCCAL INFECTIONS
		268 -
STREPTOCOCCUS PNEUMONIAE PULMONARY INFECTIONS
		269 -
NONPNEUMOCOCCAL STREPTOCOCCAL INFECTIONS AND RHEUMATIC FEVER
		270 -
ENTEROCOCCAL INFECTIONS
		271 -
CLOSTRIDIAL AND CLOSTRIDIOIDES INFECTIONS
		272- GRAM-POSITIVE ROD INFECTIONS
		273 -
DISEASES CAUSED BY NON–SPORE-FORMING ANAEROBIC BACTERIA
		274 -
NEISSERIA MENINGITIDIS INFECTIONS
		275 -
NEISSERIA GONORRHOEAE INFECTIONS
		276 -
CHANCROID
		277 -
HAEMOPHILUS AND MORAXELLA INFECTIONS
		278 -
CHOLERA AND OTHER VIBRIO INFECTIONS
		279 - CAMPYLOBACTER INFECTIONS
		280 -
ESCHERICHIA COLI ENTERIC INFECTIONS
		281 -
ENTEROBACTERALES: NON-ENTERIC INFECTIONS AND MULTIDRUG RESISTANCE
		282 -
PSEUDOMONAS AND BURKHOLDERIA INFECTIONS
		283 -
DISEASES CAUSED BY ACINETOBACTER AND STENOTROPHOMONAS SPECIES
		284 -
SALMONELLA INFECTIONS (INCLUDING ENTERIC FEVER)
		285 - SHIGELLOSIS
		286 - BRUCELLOSIS
		287 -
TULAREMIA AND OTHER FRANCISELLA INFECTIONS
		288 -
PLAGUE AND OTHER YERSINIA INFECTIONS
		289 - WHOOPING COUGH AND OTHER BORDETELLA INFECTIONS
		290 - LEGIONELLA INFECTIONS
		291 -
BARTONELLA INFECTIONS
		292 - GRANULOMA INGUINALE (DONOVANOSIS)
		293 -
MYCOPLASMA INFECTIONS
		294 -
DISEASES CAUSED BY CHLAMYDIAE
		295 -
SYPHILIS AND NONSYPHILITIC TREPONEMATOSES
		296 -
LYME DISEASE
		297 -
RELAPSING FEVER AND OTHER BORRELIA INFECTIONS
		298 -
LEPTOSPIROSIS
		299 - TUBERCULOSIS
		300 -
THE NONTUBERCULOUS MYCOBACTERIA
		301 -
LEPROSY (HANSEN DISEASE)
		302 -
RICKETTSIAL INFECTIONS
		303 -
ZOONOSES
		304 -
ACTINOMYCOSIS
		305 -
WHIPPLE DISEASE
		306 -
NOCARDIOSIS
		307 -
SYSTEMIC ANTIFUNGAL AGENTS
		308 -
ENDEMIC MYCOSES
		309 -
CRYPTOCOCCOSIS
		310
- CANDIDIASIS
		311 -
ASPERGILLOSIS
		312 - MUCORMYCOSIS
		313 -
PNEUMOCYSTIS PNEUMONIA
		314 -
MYCETOMA AND DEMATIACEOUS FUNGAL INFECTIONS
		315 -
ANTIPARASITIC THERAPY
		316 -
MALARIA
		317 -
AFRICAN SLEEPING SICKNESS
		318 -
CHAGAS DISEASE
		319 -
LEISHMANIASIS
		320 - TOXOPLASMOSIS
		321 -
CRYPTOSPORIDIOSIS
		322 -
GIARDIASIS
		323 -
AMEBIASIS
		324 -
BABESIOSIS AND OTHER PROTOZOAN DISEASES
		325 -
CESTODES
		326 -
TREMATODE INFECTIONS
		327 -
NEMATODE INFECTIONS
		328 -
ANTIVIRAL THERAPY (NON-HIV)
		329 -
THE COMMON COLD
		330 -
RESPIRATORY SYNCYTIAL VIRUS AND HUMAN METAPNEUMOVIRUS
		331 -
PARAINFLUENZA VIRAL DISEASE
		332 -
INFLUENZA
		333 -
ADENOVIRUS DISEASES
		334 -
PRE-2019 CORONAVIRUSES
		335 -
COVID-19: VIROLOGY AND PATHOLOGY
		336 -
COVID-19: EPIDEMIOLOGY, CLINICAL MANIFESTATIONS, DIAGNOSIS, COMMUNITY PREVENTION, AND PROGNOSIS
		337 -
COVID-19 TREATMENT AND VACCINATION
		338 -
MEASLES
		339 -
RUBELLA (GERMAN MEASLES)
		340 -
MUMPS
		341 -
POLYOMAVIRUSES
		342 -
PARVOVIRUS
		343 -
SMALLPOX, MONKEYPOX, AND OTHER POXVIRUS INFECTIONS
		344 -
PAPILLOMAVIRUS
		345 -
HERPES SIMPLEX VIRUS INFECTIONS
		346 -
VARICELLA-ZOSTER VIRUS(CHICKENPOX, SHINGLES)
		347 -
CYTOMEGALOVIRUS
		348 -
EPSTEIN-BARR VIRUS INFEION
		349 -
ENTEROVIRUSES
		350 -
ROTAVIRUSES, NOROVIRUSES, AND OTHER GASTROINTESTINAL VIRUSES
		351 -
VIRAL HEMORRHAGIC FEVERS
		352 -
ARBOVIRUSES CAUSING FEVER, RASH, AND NEUROLOGIC SYNDROMES
	SECTION 25: RETROVIRUSES
		353 -
EPIDEMIOLOGY AND DIAGNOSIS OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION AND ACQUIRED IMMUNODEFICIENCY SYNDROME
		354 -
PATHOBIOLOGY OF HUMAN IMMUNODEFICIENCY VIRUSES
		355 -
ACUTE CLINICAL MANIFESTATIONS AND DIAGNOSIS OF HIV
		356 -
PREVENTION OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION
		357 -
ANTIRETROVIRAL TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION
		358 -
MICROBIAL COMPLICATIONS OFHIV/AIDS
		359 -
SYSTEMIC MANIFESTATIONS OF HIV/AIDS
		360 -
RETROVIRUSES OTHER THAN HUMAN IMMUNODEFICIENCY VIRUS
	SECTION 26: BEHAVIORAL MEDICINE
		361 -
DELIRIUM AND CHANGES IN MENTAL STATUS
		362 -
PSYCHIATRIC DISORDERS IN MEDICAL PRACTICE
		363 -
NICOTINE AND TOBACCO
		364 -
ALCOHOL USE DISORDERS
		365 -
DRUG USE DISORDERS
	SECTION 27: NEUROLOGY
		366 -
APPROACH TO THE PATIENT WITH NEUROLOGIC DISEASE
		367 -
HEADACHES AND OTHER HEAD PAIN
		368 -
TRAUMATIC BRAIN INJURY AND SPINAL CORD INJURY
		369 -
MECHANICAL AND OTHER LESIONS OF THE SPINE, NERVE ROOTS, AND SPINAL CORD
		370 -
REGIONAL CEREBRAL DYSFUNCTION: HIGHER MENTAL FUNCTIONS
		371 -
COGNITIVE IMPAIRMENT AND DEMENTIA
		372 -
THE EPILEPSIES
		373 -
COMA, DISORDERS OF CONSCIOUSNESS, AND BRAIN DEATH
		374 -
SLEEP DISORDERS
		375 -
APPROACH TO CEREBROVASCULAR DISEASES
		376 -
ISCHEMIC CEREBROVASCULAR DISEASE
		377 -
HEMORRHAGIC CEREBROVASCULAR DISEASE
		378 -
PARKINSONISM
		379 -
OTHER MOVEMENT DISORDERS
		380 -
MULTIPLE SCLEROSIS AND DEMYELINATING CONDITIONS
		381 -
MENINGITIS: BACTERIAL, VIRAL,AND OTHER
		382 -
BRAIN ABSCESS AND PARAMENINGEAL INFECTIONS
		383 -
ENCEPHALITIS
		384 -
NUTRITIONAL AND ALCOHOL-RELATED NEUROLOGIC DISORDERS
		385 -
DEVELOPMENTAL AND NEUROCUTANEOUS DISORDERS
		386 -
AUTONOMIC DISORDERS
		387 -
AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISEASES
		388 -
PERIPHERAL NEUROPATHIES
		389 -
MUSCLE DISEASES
		390 -
DISORDERS OF NEUROMUSCULAR TRANSMISSION
	SECTION 28: EYE, EAR, NOSE, AND THROAT DISEASES
		391 -
DISEASES OF THE VISUAL SYSTEM
		392 -
NEURO-OPHTHALMOLOGY
		393 -
DISEASES OF THE MOUTH ANDSALIVARY GLANDS
		394 -
APPROACH TO THE PATIENT WITH NOSE, SINUS, AND EAR DISORDERS
		395 -
SMELL AND TASTE
		396 -
HEARING AND EQUILIBRIUM
		397 -
THROAT DISORDERS
	SECTION 29: MEDICAL CONSULTATION
		398 -
PRINCIPLES OF MEDICAL CONSULTATION
		399 -
PREOPERATIVE EVALUATION
		400 -
OVERVIEW OF ANESTHESIA
		401 -
POSTOPERATIVE CARE AND COMPLICATIONS
		402 -
MEDICAL CARE OF PATIENTS WITH PSYCHIATRIC DISEASES
	SECTION 30: SKIN DISEASES
		403 -
APPROACH TO SKIN DISEASES
		404 -
PRINCIPLES OF THERAPY OFSKIN DISEASES
		405- ECZEMAS, PHOTODERMATOSES, PAPULOSQUAMOUS (INCLUDING FUNGAL) DISEASES, AND FIGURATE ERYTHEMAS
		406 -
MACULAR, PAPULAR, PURPURIC, VESICULOBULLOUS, AND PUSTULAR DISEASES
		407 -
URTICARIA, DRUG HYPERSENSITIVITY RASHES, NODULES AND TUMORS, AND ATROPHIC DISEASES
		408 -
INFECTIONS, PIGMENTATION DISORDERS, REGIONAL DERMATOLOGY, AND DISTINCTIVE LESIONS IN BLACK SKIN
		409 -
DISEASES OF HAIR AND NAILS
	REFERENCE INTERVALS AND LABORATORY VALUES
	GUIDE TO THE APPROACH TO COMMON SYMPTOMS, SIGNS, LABORATORY ABNORMALITIES, SCREENING, AND TREATMENTS
	Index