Glutamine Metabolism in Mammalian Tissues

Front Matter....Pages I-IX
Front Matter....Pages 1-1
Enzymology of Glutamine....Pages 3-15
Enzymes of Renal Glutamine Metabolism....Pages 16-31
Enzymes of Cerebral Glutamine Metabolism....Pages 32-48
Glutamine Transport Across Biological Membranes....Pages 49-58
Front Matter....Pages 59-59
Metabolism of Vascular and Luminal Glutamine by Intestinal Mucosa in Vivo....Pages 61-77
Hepatic Glutamine and Ammonia Metabolism....Pages 78-97
Cellular Distribution and Regulation of Glutamine Synthetase in Liver....Pages 98-121
Liver Glutaminase....Pages 122-137
Mechanism and Control of Deprivation-Induced Protein Degradation in Liver: Role of Glucogenic Amino Acids....Pages 138-157
Front Matter....Pages 159-159
Renal Glutamine Metabolism and Hydrogen Ion Homeostasis....Pages 161-177
Effects of 2-Oxoglutarate and Glutamate on Glutamine Metabolism by Rat Kidney Mitochondria....Pages 178-186
Role of Fatty Acids in Simultaneous Regulation of Flux Through Glutaminase and Glutamine Synthetase in Rat Kidney Cortex....Pages 187-202
Front Matter....Pages 203-203
Cyclic Nucleotide Regulation of Glutamine Metabolism in Skeletal Muscle....Pages 205-222
Cerebral Glutamine/Glutamate Interrelationships and Metabolic Compartmentation....Pages 223-234
Glutamine Metabolism in Lymphoid Tissues....Pages 235-246
Glutamine Metabolism by Cultured Mammalian Cells....Pages 247-254
Front Matter....Pages 255-255
Ammonia Detoxication and Glutamine Metabolism in Severe Liver Disease and its Role in the Pathogenesis of Hepatic Encephalopathy....Pages 257-277
Molecular Targets of Anti-Glutamine Therapy with Acivicin in Cancer Cells....Pages 278-291
Back Matter....Pages 293-300