Glioma Imaging. Physiologic, Metabolic, and Molecular Approaches

Front Matter ....Pages i-xiv
 Indications and Limitations of Conventional Imaging – Current Clinical Practice in the Context of Standard Therapy  (Raymond Y. Huang, Patrick Y. Wen)....Pages 1-15
 Surrogates for Disease Status: Contrast Enhancement Including Limitations of Pseudoprogression and Pseudoresponse  (Elke Hattingen)....Pages 17-29
 The Relationship Between Biological and Imaging Characteristics in Enhancing and Nonenhancing Glioma  (Janine M. Lupo, Javier E. Villanueva-Meyer)....Pages 31-48
 Contrast-Enhanced T1-Weighted Digital Subtraction for Increased Lesion Conspicuity and Quantifying Treatment Response in Malignant Gliomas  (Benjamin M. Ellingson)....Pages 49-60
 Advanced Physiologic Imaging: Perfusion – Theory and Applications  (Philipp Kickingereder, Ji Eun Park, Jerrold L. Boxerman)....Pages 61-91
 Advanced Physiologic Imaging: Diffusion – Theory and Applications  (Peter S. LaViolette)....Pages 93-108
 Parametric Response Map (PRM) Analysis Improves Response Assessment in Gliomas  (Michael Cardenas, Craig J. Galban, Thomas L. Chenevert, Michelle Miller-Thomas, Brian D. Ross, Christina Tsien)....Pages 109-126
 Review of WHO 2016 Changes to Classification of Gliomas; Incorporation of Molecular Markers  (Derek R. Johnson, Caterina Giannini, Timothy J. Kaufmann)....Pages 127-138
 Imaging Markers of Lower-Grade Diffuse Glioma  (Melanie A. Morrison, Adam D. Waldman)....Pages 139-159
 CEST, pH, and Glucose Imaging as Markers for Hypoxia and Malignant Transformation  (Daniel Paech, Alexander Radbruch)....Pages 161-172
 MRS for D-2HG Detection in IDH-Mutant Glioma  (Ovidiu C. Andronesi, Tracy T. Batchelor, Daniel P. Cahill)....Pages 173-189
 C-13 Hyperpolarized MR Spectroscopy for Metabolic Imaging of Brain Tumors  (Pavithra Viswanath, Yan Li, Sabrina M. Ronen)....Pages 191-209
 FET and FDOPA PET Imaging in Glioma  (Norbert Galldiks, Philipp Lohmann, Francesco Cicone, Karl-Josef Langen)....Pages 211-221
 Imaging Genomics  (Cymon N. Kersch, Ramon F. Barajas Jr.)....Pages 223-239
 Radiomics and Machine Learning  (Julie Ferris, Peter D. Chang, Daniel S. Chow)....Pages 241-249
 Immunotherapy and Gliomas  (Elise Wang, Robert J. Young, Ankush Bhatia)....Pages 251-265
 The Path Forward: The Standardized Brain Tumor Imaging Protocol (BTIP) for Multicenter Trials  (Benjamin M. Ellingson, Marion Smits)....Pages 267-282
Back Matter ....Pages 283-286