Gene Technology: Stem Cell and Leukemia Research

Front Matter....Pages I-XII
Front Matter....Pages 1-1
Hematopoietic Differentiation of Embryonal Stem Cells in vitro .....Pages 3-10
Post-irradiated canine serum (PICS-J) stimulates megakaryocyte (MK) progenitors and thrombopoiesis in-vitro....Pages 11-27
The Adhesion Molecules, PECAM-1, ICAM-3 and CD33, on CD34 + Haematopoietic Progenitor Cells....Pages 29-76
Hematopoietic stem cell: developmental potential and proliferative activity....Pages 77-90
The Effect of Methylprednisolone on Bone Marrow and Spleen Clonogenic Fibroblasts in Humans....Pages 91-97
Umbilical cord blood: Morphological composition and functional characteristics....Pages 99-106
Stroma cell dependent leukemias Growth of PGM-1 leukemia cells on stromal layers....Pages 107-116
Front Matter....Pages 117-117
The Role of Non-receptor Protein Tyrosine Kinases in Receptor Mediated Cellular Activation and Immunodeficiency Disease....Pages 119-134
Directed Gene Trapping in Embryonic Stem Cells....Pages 135-144
Molecular Basis of Genetic Disorders of Pigmentation in Humans and Mice....Pages 145-174
MDR-1 Gene Expression in Chronic Myelogenous Leukemia: Prognostic Marker of the Disease....Pages 175-179
Front Matter....Pages 181-181
Towards Gene Therapy for Haemophilia B....Pages 183-188
Inhibition of autocrine TGF-ß in CD34+ human progenitor cells reveals their potentiality to engraft adults and improves gene transfer efficiency....Pages 189-192
Gene Transfer into Hemopoietic Progenitors: Implications for Bone Marrow Transplantation....Pages 193-202
Erythropoietin and the ENV gp55 of the Spleen Focus Forming Virus (SFFV) Interact Differently with Erythroid Cells in the Mouse and in Tissue Culture....Pages 203-218
Contribution of the Retroviral Leader to Gene Transfer and Expression in Packaging Cells and Myeloid Stem and Progenitor Cells....Pages 219-228
Site-directed Mutagenesis of the cGMP Phosphodiesterase Inhibitory g Subunit from Bovine Rods: New Mechanisms of Catalytic Subunits Inhibition and Activation....Pages 229-244
Front Matter....Pages 245-245
Genetic Approaches to Defining Signaling by the CML-Associated Tyrosine kinase BCR-ABL1....Pages 247-262
Analysis of Oncosuppressor Gene Function in the Mouse by Gene Targeting....Pages 263-281
Front Matter....Pages 283-283
Cloning of retroviral insertion sites possibly involved in growth-factor autonomy....Pages 285-293
Front Matter....Pages 283-283
Function of the IL-3 receptor system in hematopoiesis....Pages 295-307
Altered Growth Factor Response in Myeloid Progenitor Cell Mutants Derived after Retroviral Insertlonal Mutagenesis....Pages 307-319
Signaling by the Erythropoietin receptor in retrovirally transduced normal hematopoietic progenitors: A conserved proline-rich motif is required for association with JAK2....Pages 321-331
Spontaneous Knockout of CSF-1 Gene in the Mouse as a Model to Study the Organization of the Macrophage System....Pages 333-350
Front Matter....Pages 351-351
Lifting a tip of the veil of human minor Histocompatibility antigens....Pages 353-359
Immune escape through T cell antagonism?....Pages 361-368
The privilege of expressing CD44v - used by immune cells, misused by tumour cells....Pages 369-379
Transplantation Immunology: Peptides in the groove cause histocompatibility....Pages 381-396
Front Matter....Pages 397-397
Coupling of Membrane Pathology and DNA Damage in Irradiated Lymphoid Cell Population....Pages 399-404
Effects of Radiation on the Plasma Membrane and Expression of Membrane Bound Hematopoietic Cytokines....Pages 405-418
Front Matter....Pages 419-419
Prognostic Value of Day 8 Peripheral Blood Responce for Children with Acute Lymphocytic Leukemia....Pages 421-428
GM-CSF in Addition to Chemotherapy of ALL for Kinetics Based Protection of Stem Cells and Stimulation of Haemopoiesis.A randomized Study....Pages 429-440
Cytogenetic Abnormalities and Their Clinical and Prognosti Value in Acute Leukemia....Pages 441-447
Production of Interleukin-2 and Natural Killer (NK) Activity in Patients with Multiple Myeloma....Pages 449-453
Multiple Myeloma Associated with Amyloidosis....Pages 455-460
Distribution of HLA-DRB1 Alleles in Patients with Chronic Myelogenous Leukemia Differs from That in Healthy Donors....Pages 461-465
The Relationship of MDR-1 Gene Expression and Chemotherapy Regimens in Acute Leukemia....Pages 467-473
Immunophenotyping of blast crisis during the chronic myelogenous leukemia....Pages 475-484
The treatment of acute lymphoblastic leukemia in children according to BFM protocols....Pages 485-491
Front Matter....Pages 493-493
Carcinoembryonic antigen (CEA) in blood serum of patients with bone marrow transplantation....Pages 495-498
Front Matter....Pages 493-493
Cytogenetic Monitoring in The Post BMT Period....Pages 499-504
First Experience in the Field of Bone Marrow Transplantation at the St.-Peterburg BMT Center....Pages 505-511
Immunoglobulin E Levels in Allogenic BMT....Pages 513-517
Prognostic Factors and Indications for Haemopoietic Stem Cells Transplantation in Patients with Multiple Myeloma....Pages 519-529
Mobilization of Progenitor Cells for Autologous and Allogeneic Transplantation....Pages 531-536
Transfusion problems of allogenic bone marrow transplantation (BMT)....Pages 537-540
Back Matter....Pages 541-546