G Protein Coupled Receptors: Trafficking and Oligomerization

Content: 
Series Page
Page ii

Copyright
Page iv

Contributors
Pages xiii-xviii

Preface
Page xix
P. Michael Conn

Methods in Enzymology
Pages xxi-lvi

Chapter One - Therapeutic Rescue of Misfolded/Mistrafficked Mutants: Automation-Friendly High-Throughput Assays for Identification of Pharmacoperone Drugs of GPCRs
Pages 3-16
David C. Smithson, Jo Ann Janovick, P. Michael Conn

Chapter Two - Trafficking of the Follitropin Receptor
Pages 17-45
Alfredo Ulloa-Aguirre, James A. Dias, George Bousfield, Ilpo Huhtaniemi, Eric Reiter

Chapter Three - Single-Molecule Imaging Technique to Study the Dynamic Regulation of GPCR Function at the Plasma Membrane
Pages 47-67
B.E. Snaar-Jagalska, A. Cambi, T. Schmidt, S. de Keijzer

Chapter Four - GPCR Oligomerization and Receptor Trafficking
Pages 69-90
Richard J. Ward, Tian-Rui Xu, Graeme Milligan

Chapter Five - ОІ-Arrestins and G Protein-Coupled Receptor Trafficking
Pages 91-108
Dong Soo Kang, Xufan Tian, Jeffrey L. Benovic

Chapter Six - Tracking Cell Surface Mobility of GPCRs Using О±-Bungarotoxin-Linked Fluorophores
Pages 109-129
Saad Hannan, Megan E. Wilkins, Philip Thomas, Trevor G. Smart

Chapter Seven - Regulatory Mechanism of G Protein-Coupled Receptor Trafficking to the Plasma Membrane: A Role for mRNA Localization
Pages 131-150
Kusumam Joseph, Eleanor K. Spicer, Baby G. Tholanikunnel

Chapter Eight - Dissecting Trafficking and Signaling of Atypical Chemokine Receptors
Pages 151-168
Elena Borroni, Cinzia Cancellieri, Massimo Locati, Raffaella Bonecchi

Chapter Nine - Systematic and Quantitative Analysis of G Protein-Coupled Receptor Trafficking Motifs
Pages 171-187
Carl M. Hurt, Vincent K. Ho, Timothy Angelotti

Chapter Ten - Identification of Endoplasmic Reticulum Export Motifs for G Protein-Coupled Receptors
Pages 189-202
Guangyu Wu

Chapter Eleven - Amino Acid Residues of G-Protein-Coupled Receptors Critical for Endoplasmic Reticulum Export and Trafficking
Pages 203-216
Motonao Nakamura, Daisuke Yasuda, Nobuaki Hirota, Teruyasu Yamamoto, Satoshi Yamaguchi, Takao Shimizu, Teruyuki Nagamune

Chapter Twelve - G-Protein-Coupled Heteromers: Regulation in Disease
Pages 219-238
Ivone Gomes, Achla Gupta, Lakshmi A. Devi

Chapter Thirteen - Hetero-oligomerization and Specificity Changes of G Protein-Coupled Purinergic Receptors: Novel Insight into Diversification of Signal Transduction
Pages 239-257
Tokiko Suzuki, Kazunori Namba, Natsumi Mizuno, Hiroyasu Nakata

Chapter Fourteen - Bimolecular Fluorescence Complementation Analysis of G Protein-Coupled Receptor Dimerization in Living Cells
Pages 259-279
Karin F.K. Ejendal, Jason M. Conley, Chang-Deng Hu, Val J. Watts

Chapter Fifteen - G Protein–Coupled Receptor Heterodimerization in the Brain
Pages 281-294
Dasiel O. Borroto-Escuela, Wilber Romero-Fernandez, Pere Garriga, Francisco Ciruela, Manuel Narvaez, Alexander O. Tarakanov, MiklГіs Palkovits, Luigi F. Agnati, Kjell Fuxe

Chapter Sixteen - Experimental Strategies for Studying G Protein-Coupled Receptor Homo- and Heteromerization with Radioligand Binding and Signal Transduction Methods
Pages 295-310
Roberto Maggio, Cristina Rocchi, Marco Scarselli

Chapter Seventeen - Analysis of GPCR Dimerization Using Acceptor Photobleaching Resonance Energy Transfer Techniques
Pages 311-327
Marta Busnelli, Mario Mauri, Marco Parenti, Bice Chini

Chapter Eighteen - Techniques for the Discovery of GPCR-Associated Protein Complexes
Pages 329-345
Avais Daulat, Pascal Maurice, Ralf Jockers

Chapter Nineteen - Expression, Purification, and Analysis of G-Protein-Coupled Receptor Kinases
Pages 347-366
Rachel Sterne-Marr, Alison I. Baillargeon, Kevin R. Michalski, John J.G. Tesmer

Chapter Twenty - Modern Methods to Investigate the Oligomerization of Glycoprotein Hormone Receptors (TSHR, LHR, FSHR)
Pages 367-383
Marco Bonomi, Luca Persani

Author Index
Pages 385-405

Subject Index
Pages 407-422