Fundamental Problems in Breast Cancer: Proceedings of the Second International Symposium on Fundamental Problems in Breast Cancer Held at Banff, Alberta, Canada April 26–29, 1986

Front Matter....Pages i-xviii
Front Matter....Pages 1-1
Pathology of Breast Cancer Detected by Imaging Techniques....Pages 3-10
Screening for Breast Cancer: An Overview....Pages 11-16
Research in New Imaging Methods for Detection of Breast Cancer....Pages 17-24
The Canadian National Breast Screening Study: Current Status....Pages 25-27
Natural History of Mammary Tumors Seen in a Breast Center....Pages 29-37
An Educational and Diagnostic Breast Center in Edmonton: A Preliminary Report of the First Year....Pages 39-46
The Breast Center—A Multidisciplinary Model....Pages 47-57
Multimodality Breast Imaging: The Value of Diaphanography....Pages 59-68
Comparative Value of Diaphanoscopy Mammography, and Thermography for Breast Cancer Screening....Pages 69-73
Finding Earlier Nonpalpable Breast Cancers Using Hooked Wire Directed Biopsy and a Modified Overpenetrated Mammographic Technique....Pages 75-89
The Significance of Tumor Size in Stage I Invasive Breast Cancer....Pages 91-95
The Impact of Breast Cancer Screening on Surgical Treatment Policies....Pages 97-104
Survival of Patients with Breast Cancer Detected Between Mammographic Screenings....Pages 105-111
Intraductal Breast Carcinoma—What Constitutes Adequate Treatment?....Pages 113-124
Front Matter....Pages 125-125
Endocrine and other Influences in the Normal Development of the Breast....Pages 127-137
Endocrine Prevention of Breast Cancer by Tamoxifen....Pages 139-143
Mechanisms of Regression and Revised Approaches to Endocrine Therapy....Pages 145-153
Growth Factors, Oncogenes, and Breast Cancer....Pages 155-171
Estrogenic Recruitment Followed by Chemotherapy in Breast Cancer: Experimental and Clinical Results....Pages 173-176
Relationship of Breast Cancer Hormone Receptors, Menopausal Status, and Adjuvant Therapy to Site(s) of Recurrence and Survival....Pages 177-185
Front Matter....Pages 125-125
Cyclical Use of Tamoxifen and High-Dose Medroxyprogesterone Acetate in Advanced Breast Cancer....Pages 187-191
An Inverse Relationship Between Intracellular Prolactin and Growth Hormone and Estrogen Receptor Status in Human Breast Cancers....Pages 193-196
Steroid Receptors in Breast Cancer: Kuwait Experience....Pages 197-198
Front Matter....Pages 199-199
Breast Cancer Trials of the Ludwig and International Breast Cancer Study Group....Pages 201-222
The Validity of Summing Results of Clinical Trials in Breast Cancer....Pages 223-227
Cost-Benefit Analysis of Chemotherapy Trials....Pages 229-234
Adjuvant Therapy in Postmenopausal Patients with Operable Breast Cancer....Pages 235-238
Front Matter....Pages 239-239
Autonomic Insufficiency in Patients with Advanced Breast Cancer....Pages 241-247
Brachial Plexopathy in Patients with Breast Cancer....Pages 249-257
Lymphedema—Its Treatment....Pages 259-263
Competing Causes of Death in Breast Cancer Patients....Pages 265-272
Breast Cancer Profile in India: Experiences at the Tata Memorial Hospital, Bombay....Pages 273-279
Front Matter....Pages 281-281
Tumor Metastasis: Biology and Experimental Therapeutic Approaches....Pages 283-298
The Detection and Evaluation of Bone Marrow Micrometastases in Primary Breast Cancer....Pages 299-301
Physiology of Bone and Metabolic Approaches to the Treatment of Skeletal Metastases....Pages 303-322
Expression of the ras Oncogene p 21 Protein in Human Breast Tumors and in Several Benign Conditions Using the Y13 259 Monoclonal Antibody....Pages 323-325
Synergistic Effect of Cell Kinetics-Directed Chemo-Endocrine Therapy on Experimental Mammary Tumors....Pages 327-329
Front Matter....Pages 331-331
The Natural History of Human Breast Cancer: Implications for Patient Management....Pages 333-347
Assessment of Treatment in the Clinic....Pages 349-367
Treatment of Metastatic Breast Cancer as a Guide to Design of Adjuvant Therapy Trials....Pages 369-372
Front Matter....Pages 331-331
Problems Associated with the Assessment of Patients with Metastatic Breast Cancer: Can Past Experience Teach us to do Better Clinical Trials?....Pages 373-382
Preoperative Combined Modality (Neoadjuvant) Therapy for Locally Advanced Inoperable Breast Cancer (LAIBC)....Pages 383-389
Priorities in Cancer Control Strategies in India....Pages 391-399
The Epidemiology of Breast Cancer from an African Perspective....Pages 401-403
Summary: Breast Cancer in the Eighties....Pages 405-407