Fundamental Pharmacology for Pharmacy Technicians

Title Page......Page 2
Copyright......Page 3
Contents......Page 6
Preface......Page 27
Acknowledgments......Page 29
About the Author......Page 31
SECTION I: GENERAL ASPECTS OF
PHARMACOLOGY......Page 32
CHAPTER 1: Introduction to
Pharmacology, Drug
Legislation, and Regulation......Page 33
The History of Pharmacology......Page 34
Drug Product Development......Page 35
Nonprescription Drugs......Page 36
Federal Drug Legislation......Page 37
Review Questions......Page 39
CHAPTER 2: Drug Sources
and Dosage Forms......Page 43
Drug Names......Page 44
Drug Sources......Page 45
Dosage Forms of Drugs......Page 46
Review Questions......Page 53
CHAPTER 3: Biopharmaceutics......Page 57
Overview......Page 58
Pharmacokinetics......Page 59
Drug Action......Page 66
Review Questions......Page 72
SECTION II: PHARMACOLOGY RELATED
TO SPECIFIC BODY SYSTEMS
AND DISORDERS......Page 76
CHAPTER 4: Drug Therapy for the Nervous
System: Antipsychotic and
Antidepressant Drugs......Page 77
Anatomy Review......Page 79
Neurotransmitters......Page 85
Mental Disorders......Page 87
Antipsychotic Drugs......Page 88
Mood Altering Drugs......Page 90
Antidepressants......Page 92
Exploring the Web......Page 99
Review Questions......Page 100
CHAPTER 5: Drug Therapy for the
Nervous System: Antianxiety
and Hypnotic Drugs......Page 103
Anxiety......Page 104
Sedatives and Hypnotics......Page 106
Exploring the Web......Page 114
Review Questions......Page 115
CHAPTER 6: Drug Therapy for the Autonomic Nervous System......Page 118
Anatomy Review......Page 119
Neurotransmitters Associated with
the Autonomic Nervous System......Page 122
Receptors......Page 123
Drugs Affecting the Autonomic Nervous System......Page 125
Review Questions......Page 133
CHAPTER 7: Drug Therapy for
Parkinson’s and
Alzheimer’s Diseases......Page 137
Parkinson’s Disease......Page 138
Pharmacotherapy for Parkinson’s Disease......Page 139
Alzheimer’s Disease......Page 142
Pharmacotherapy for Alzheimer’s Disease......Page 143
Review Questions......Page 145
CHAPTER 8: Drug Therapy
for Seizures......Page 148
Classifications of Seizures......Page 149
Anti-Seizure Drugs......Page 150
Exploring the Web......Page 156
Review Questions......Page 157
CHAPTER 9: Anesthetic Drugs......Page 160
Preanesthetic Medications......Page 161
Stages and Planes of Anesthesia......Page 162
General Anesthetics......Page 163
Local Anesthetics......Page 165
Malignant Hyperthermia......Page 170
Review Questions......Page 171
CHAPTER 10: Drug Therapy for the
Musculoskeletal System......Page 174
Anatomy Review......Page 175
Musculoskeletal Disorders......Page 178
Skeletal Muscle Relaxants......Page 180
Drugs for Gouty Arthritis......Page 187
Review Questions......Page 189
CHAPTER 11: Drug Therapy
for Cardiovascular
Disorders......Page 193
Anatomy Review......Page 194
Ischemic Heart Disease......Page 197
Antianginal Drug Therapy......Page 200
Myocardial Infarction......Page 205
Cardiac Arrhythmias......Page 206
Antiarrhythmic Drugs......Page 207
Cardiac Glycosides......Page 212
Review Questions......Page 214
CHAPTER 12: Antihypertensive Agents
and Hyperlipidemia......Page 217
Overview......Page 218
Hypertension......Page 219
Antihypertensive Therapy......Page 221
Hyperlipidemia......Page 234
Antihyperlipidemic Drugs......Page 235
Review Questions......Page 242
CHAPTER 13: Anticoagulant Drugs......Page 246
Blood Coagulation......Page 247
Anticoagulant Drugs......Page 249
Antiplatelet Drugs......Page 252
Thrombolytic Drugs......Page 254
Review Questions......Page 257
CHAPTER 14: Drug Therapy for
Allergies and Respiratory
Disorders......Page 260
Overview......Page 261
Anatomy Review......Page 262
Chemical Mediators......Page 264
Allergic Reaction......Page 265
Anti-allergic Agents......Page 266
Asthma......Page 269
Anti-asthma Agents......Page 270
Decongestants......Page 277
Antitussives, Expectorants, and Mucolytics......Page 279
Chronic Obstructive Pulmonary Disease......Page 280
Drugs for Smoking Cessation......Page 281
Review Questions......Page 284
CHAPTER 15: Drug Therapy for
Gastrointestinal
Disorders......Page 288
Anatomy Review......Page 289
Acid Peptic Diseases......Page 291
Pancreatic Disorders......Page 298
Gallstone-solubilizing Agents......Page 300
Diarrhea......Page 301
Gas Retention......Page 303
Constipation......Page 304
Vomiting......Page 307
Adsorbents......Page 310
Review Questions......Page 312
CHAPTER 16: Hormonal Th erapy
for Endocrine Gland
Disorders......Page 316
Anatomy Review......Page 318
Hormonal Regulation......Page 320
Hormones......Page 321
Alterations in the Function of the Pituitary Gland......Page 327
Alterations in the Function of the Thyroid Gland......Page 329
Alterations in Function of the Parathyroid Gland......Page 333
Alterations in Function of the Adrenal Glands......Page 334
Alterations in the Function of the Pancreas......Page 337
Summary......Page 342
Review Questions......Page 343
CHAPTER 17: Hormones of the
Reproductive System
and Contraceptives......Page 346
Anatomy Review......Page 347
Gonadal Hormones......Page 349
Oral Contraceptives......Page 351
Drugs Used During Labor and Delivery......Page 357
Drugs Used in the Treatment of Sexually
Transmitted Diseases......Page 359
Male Sex Hormones......Page 360
Anabolic Steroids......Page 362
Androgen Hormone Inhibitors......Page 363
Exploring the Web......Page 364
Review Questions......Page 365
CHAPTER 18: Diuretics......Page 368
Anatomy Review......Page 369
Diuretics......Page 373
Review Questions......Page 381
SECTION III: PHARMACOLOGY FOR
DISORDERS AFFECTING
MULTI-BODY SYSTEMS......Page 386
CHAPTER 19: Vitamins, Minerals,
and Nutritional
Supplements......Page 387
Vitamins......Page 390
Minerals and Electrolytes......Page 396
Food Labeling......Page 400
Food Additives......Page 401
Pharma Food......Page 402
Review Questions......Page 404
CHAPTER 20: Antineoplastic Agents......Page 408
Characteristics of Cancer......Page 409
Antineoplastic Agents......Page 411
Review Questions......Page 422
CHAPTER 21: Analgesics......Page 426
Analgesics......Page 427
Migraine Headaches......Page 437
Exploring the Web......Page 440
Review Questions......Page 441
CHAPTER 22: Anti-infectives
and Systemic
Antibacterial Agents......Page 444
Infections......Page 445
Microorganisms......Page 447
Principles of Anti-infective Therapy......Page 449
Antibacterial Agents......Page 451
Antitubercular Drugs......Page 470
Review Questions......Page 474
CHAPTER 23: Antiviral, Antifungal,
and Antiprotozoal Agents......Page 478
Viruses......Page 479
Fungi......Page 487
Protozoa......Page 492
Review Questions......Page 497
SECTION IV: PHARMACOLOGY FOR
SPECIFIC POPULATIONS......Page 500
CHAPTER 24: Drug Therapy
During Pregnancy
and Lactation......Page 501
Pharmacokinetics During Pregnancy......Page 502
Pregnancy Drug Categories......Page 503
Lactation Drug Categories......Page 506
Common Conditions Affecting
the Pregnant Patient......Page 507
Review Questions......Page 510
CHAPTER 25: Drug Therapy for Pediatric Patients......Page 514
Overview......Page 515
Unique Characteristics in Pediatric
Medication Administration......Page 516
Fever......Page 519
Childhood Respiratory Diseases......Page 520
Common Childhood Illnesses......Page 524
Cardiovascular and Blood Disorders......Page 527
Infectious Diseases......Page 530
Exploring the Web......Page 533
Review Questions......Page 534
CHAPTER 26: Drug Therapy
in Geriatrics......Page 537
Aging Patients......Page 538
Physiologic Aging......Page 539
Common Disorders in the Elderly......Page 545
Drug Interactions......Page 551
Specific Drug Considerations for the Elderly......Page 554
Review Questions......Page 560
Appendices A-K......Page 564
Answer Keys......Page 594
Glossary......Page 602
Index......Page 616