Fundamental Immunology

Fundamental Immunology
CONTRIBUTING AUTHORS
PREFACE
ACKNOWLEDGMENTS
CONTENTS
SECTION I Introduction to Immunology
	The Immune System
	History of Immunology
SECTION II Organization and Evolution of the
	Lymphoid Tissues and Organs
	Evolution of the Immune System
SECTION III Immunoglobulins and B Lymphocytes
	Immunoglobulins: Structure and Function
	Immunoglobulins: Molecular Genetics
	Antigen–Antibody Interactions and Monoclonal Antibodies
	B-Lymphocyte Development and Biology
	B-Lymphocyte Receptors, Signaling Mechanisms, and Activation
	B-Lymphocyte Responses
SECTION IV T-Lymphocytes
	T-Cell Antigen Receptors
	Mechanisms of T-Lymphocyte Signaling and Activation
	T-Lymphocyte Developmental Biology
	Peripheral T Lymphocyte Responses and Function
SECTION V The Intersection of Innate and Adaptive Immunity
	The Innate Immune System
	Dendritic Cells
	Natural Killer Cells
	CD1d–Restricted Natural Killer T Cells
	Macrophages and Phagocytosis
	Granulocytes and Mast Cells
	The Major Histocompatibility Complex and Its Proteins
	Antigen Processing and Presentation
SECTION VI Induction, Regulation, and Effector Functions of the Immune Response
	Immunogenicity and Antigen Structure
	Fc Receptors and Their Role in Immune Regulation and Infl ammation
	Type I Cytokines and Interferons, and Their Receptors
	The Interleukin-1 Family
	Tumor Necrosis Factor–Related Cytokines in Immunity
	Chemokines
	Helper T-Cell Differentiation and Plasticity
	Programmed Cell Death
	Immunologic Memory
	Immunologic Tolerance
	Regulatory/Suppressor T Cells
	The Mucosal Immune System
	Neurophysiologic Refl ex Mechanisms in Immunology
	Complement
	Cell-Mediated Cytotoxicity
SECTION VII Immunity to Infectious Agents
	The Immune Response to Parasites
	Immunity to Viruses
	Immunity to Intracellular Bacteria
	Immunity to Extracellular Bacteria
	Immunology of Human Immunodefi ciency Virus Infection
	Vaccines
SECTION VIII Immunologic Mechanisms in Disease
	Autoimmunity and Autoimmune Diseases
	Immunologic Mechanisms of Allergic Disorders
	Transplantation Immunology
	Cancer Immunology
	Inborn Errors of Immunity
INDEX
REFERENCES
	CHAPTER 2 REFERENCES
	CHAPTER 3 REFERENCES
	CHAPTER 4 REFERENCES
	CHAPTER 5 REFERENCES
	CHAPTER 6 REFERENCES
	CHAPTER 7 REFERENCES
	CHAPTER 8 REFERENCES
	CHAPTER 9 REFERENCES
	CHAPTER 10 REFERENCES
	CHAPTER 11 REFERENCES
	CHAPTER 12 REFERENCES
	CHAPTER 13 REFERENCES
	CHAPTER 14 REFERENCES
	CHAPTER 15 REFERENCES
	CHAPTER 16 REFERENCES
	CHAPTER 17 REFERENCES
	CHAPTER 18 REFERENCES
	CHAPTER 19 REFERENCES
	CHAPTER 20 REFERENCES
	CHAPTER 21 REFERENCES
	CHAPTER 22 REFERENCES
	CHAPTER 23 REFERENCES
	CHAPTER 24 REFERENCES
	CHAPTER 25 REFERENCES
	CHAPTER 26 REFERENCES
	CHAPTER 27 REFERENCES
	CHAPTER 28 REFERENCES
	CHAPTER 29 REFERENCES
	CHAPTER 30 REFERENCES
	CHAPTER 31 REFERENCES
	CHAPTER 32 REFERENCES
	CHAPTER 33 REFERENCES
	CHAPTER 34 REFERENCES
	CHAPTER 35 REFERENCES
	CHAPTER 36 REFERENCES
	CHAPTER 37 REFERENCES
	CHAPTER 38 REFERENCES
	CHAPTER 39 REFERENCES
	CHAPTER 40 REFERENCES
	CHAPTER 41 REFERENCES
	CHAPTER 42 REFERENCES
	CHAPTER 43 REFERENCES
	CHAPTER 44 REFERENCES
	CHAPTER 45 REFERENCES
	CHAPTER 46 REFERENCES
	CHAPTER 47 REFERENCES
	CHAPTER 48 REFERENCES