Functional Tissue Engineering

Preliminaries......Page 1
Preface......Page 5
Contents......Page 9
1 How Does Nature Build a Tissue......Page 18
2 Ligament Healing Present Status and the Future of Functional Tissue Engineering......Page 32
3 Native Properties of Cardiovascular Tissues Guidelines for Functional Tissue Engineering......Page 50
4 Functional Properties of Native Articular Cartilage......Page 61
5 Excitability and Contractility of Skeletal Muscle Measurements and Interpretations......Page 84
6 Functional Requirements for the Engineering of a Blood Vessel Substitute......Page 102
7 In Vivo Force and Strain of Tendon Ligament and Capsule......Page 111
8 Requirements for Biological Replacement of the Articular Cartilage at the Knee Joint......Page 121
9 Functional Requirements Cartilage......Page 132
10 Design Parameters for Functional Tissue Engineering......Page 144
11 Tissue Engineering a Heart: Critical Issues......Page 154
12 Design Parameters for Engineering Bone Regeneration......Page 161
13 Tissue Engineering of Bone: The Potential Uses of Gene......Page 177
14 Engineered Skeletal Muscle Functional Tissues Organs and Interfaces......Page 193
15 Bioengineering the Growth of Articular Cartilage......Page 209
16 Functional Tissue Engineering Assessment of Function in Tendon and Ligament Repair......Page 228
17 The Role of Mechanical Forces in Tissue Engineering of Articular Cartilage......Page 242
18 Biomechanics of Native and Engineered Heart Valves Tissues......Page 258
19 Assessment of Function in Tissue Engineered Vascular Grafts......Page 273
20 Assessment of the Performance of Engineered Tissues in Humans Requires the Development of Highly Sensitive and Quantitative Noninvasive Outcome Measures......Page 283
21 Functional Tissue Engineering and the Role of Biomechanical Signaling in articular Cartilage Repair......Page 292
22 Regulation of Cellular Response to Mechanical Signals by Matrix Design......Page 306
23 Artificial Soft Tissue Fabrication from Cell Contracted Biopolymers......Page 320
24 Cytomechanics Signaling to Mechanical Load in Connective Tissue Cells and Role in Tissue Engineering......Page 333
25 The Role of Biomechanics in Analysis of Cardiovascular Diseases Regulation of the Fluid Shear Response by Inflammatory Mediators......Page 352
26 A Full Spectrum of Functional Tissue engineered Blood Vessels From Macroscopic to Microscopic......Page 362
27 Engineering Functional Cartilage and Cardiac Tissue In Vitro Culture Parameters......Page 375
28 Tissue Engineering Skeletal Muscle......Page 392
29 From Concept Toward the Clinic Preclinical Evaluation of Tissue Engineered Constructs......Page 410
30 Trends in the FDA......Page 415
Index......Page 420