Frontiers in Drug Design and Discovery, Volume (4)

Contents......Page 2
Present and Future Mass Spectrometry-Based Approaches for Exploratory Drug Metabolism and Pharmacokinetic Studies......Page 11
Glutathione Transferases in Drug Discovery and Development: Towards Safer and Efficacious Drugs......Page 33
New Sampling Techniques for Pharmacokinetic- Pharmacodynamic Modeling......Page 53
Role of Inflammatory Biomarkers in Establishing PK/PD Relationships and Target Organ Toxicity......Page 91
Important Drug Interactions for Clinical Oncologists......Page 107
Pharmacogenomic Considerations in Breast Cancer Management......Page 132
More Than Skin Deep: The Human Skin Tissue Equivalent as an Advanced Drug Discovery Tool......Page 145
Across Skin Barrier: Known Methods, New Performances......Page 172
The Tape Stripping Method as a Valuable Tool for Evaluating Topical Applied Compounds......Page 199
Methylphenidate Extended-Release Capsules: A New Formulation for Attention-Deficit Hyperactivity Disorder......Page 238
Osmotic-Controlled Release Oral Delivery System (OROS Technology) in Chronic Pain Management......Page 257
Drug Delivery Systems Prepared by Membrane Emulsification......Page 283
In Silico ADME Approaches......Page 301
Advances in ADMET Predictions and Modeling: Rapid Drug Discovery Efforts in 21st Centuries......Page 343
Computational Intelligence Methods for ADMET Prediction......Page 361
Data Modeling and Chemical Interpretation of ADME Properties Using Regression and Rule Mining Techniques......Page 388
A Review on Virtual Reality and Haptics Approaches in Drug Design and Discovery......Page 439