Fighting multidrug resistance with herbal extracts, essential oils and their components

Front Cover......Page 1
Fighting Multidrug Resistance With Herbal Extracts,Essential Oils and Their Components
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Copyright
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Contents......Page 6
Preface......Page 10
List of Figures......Page 12
List of Tables......Page 14
Contributors......Page 16
BACKGROUND......Page 20
BACTERIAL INTERFERENCE......Page 22
BACTERIOPHAGE THERAPY......Page 23
HERB AND PLANT EXTRACTS......Page 24
ESSENTIAL OILS......Page 25
References......Page 26
INTRODUCTION......Page 30
PLANTS EXTRACTS WITH ANTI-METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS EFFECTS......Page 31
MOLECULES WITH ANTI-METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ACTIVITY DERIVED FROM PLANTS......Page 32
SYNERGY BETWEEN NATURAL PRODUCTS AND ANTIBIOTICS USED FOR THE TREATMENT OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS......Page 34
OTHER NATURAL SOURCES WITH EFFECTS ON ANTI-METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS......Page 36
CONCLUSIONS......Page 38
References......Page 39
INTRODUCTION......Page 42
MEDICINAL PLANT METABOLITES USED IN THE FIGHT AGAINST VANCOMYCIN-RESISTANT ENTEROCOCCI......Page 43
CONCLUSION......Page 47
References......Page 48
INTRODUCTION......Page 50
CONVENTIONAL ANTIFUNGAL DRUGS......Page 52
ANTIFUNGAL ACTIVITY OF NATURAL PRODUCTS OBTAINED FROM PLANTS......Page 54
References......Page 60
TUBERCULOSIS: ONE OF THE FORGOTTEN DISEASES......Page 64
ORTHODOX PHARMACEUTICALS USED IN THE TREATMENT OF TUBERCULOSIS......Page 65
WORLD TRADITIONS AND ETHNOPHARMACOLOGY OF TUBERCULOSIS......Page 70
CHEMICAL CLASSES AS PROMISING LEADS......Page 75
THE WAY FORWARD......Page 79
References......Page 80
INTRODUCTION......Page 84
ESSENTIAL OIL COMPOSITION......Page 85
PERSPECTIVE ON THE USE OF ESSENTIAL OILS......Page 87
BACTERIAL CELL TARGETS AND ANTIBIOTIC MODE OF ACTION......Page 89
MECHANISMS OF ANTIBIOTIC RESISTANCE......Page 93
CONTROLLING MULTIDRUG-RESISTANT BACTERIA......Page 95
SYNERGISTIC ACTIVITY BETWEEN ESSENTIAL OILS AND ANTIBIOTICS......Page 103
DEVELOPMENT OF RESISTANCE UNDER CONTINUOUS EXPOSURE TO ESSENTIAL OILS?......Page 104
References......Page 105
INTRODUCTION......Page 114
TRADITIONAL ANTILEISHMANIAL DRUGS......Page 115
RECENT ANTILEISHMANIAL DRUGS......Page 116
NATURAL PRODUCTS AS SOURCES OF NEW ANTILEISHMANIAL COMPOUNDS......Page 117
CONCLUSIONS AND FUTURE PERSPECTIVES......Page 121
References......Page 122
INTRODUCTION: SCHISTOSOMIASIS......Page 128
SCHISTOSOMICIDAL DRUGS AND RESISTANCE......Page 129
NATURAL PRODUCTS AS SCHISTOSOMICIDAL AGENTS......Page 130
NATURAL PLANT COMPOUNDS WITH SCHISTOSOMICIDAL ACTIVITY......Page 137
CONCLUSIONS......Page 147
References......Page 148
INTRODUCTION......Page 154
USE OF TRADITIONAL BOTANICAL MEDICINES AS ANTIBACTERIAL AGENTS......Page 155
METHICILLIN- AND VANCOMYCIN-RESISTANT STAPHYLOCOCCUS AUREUS......Page 156
IN VITRO STUDIES ON THE USE OF BOTANICAL EXTRACTS FOR TREATING METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AND VANCOMYCIN-R .........Page 157
HUMAN STUDIES ON THE USE OF BOTANICALS FOR TREATING METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS INFECTIONS......Page 161
References......Page 164
INTRODUCTION......Page 168
MECHANISM OF ACTION OF ESSENTIAL OILS ON MULTIDRUG-RESISTANT BACTERIA......Page 170
COMBINING ESSENTIAL OILS WITH ANTIBIOTICS AND OTHER ANTIMICROBIAL AGENTS......Page 171
FUTURE PERSPECTIVES......Page 178
References......Page 180
GENERAL INTRODUCTION......Page 184
ANTIMICROBIAL AGENTS FROM PLANT SOURCES......Page 185
FUTURE DIRECTIONS: SYNERGISTIC THERAPY......Page 190
FUTURE PERSPECTIVES......Page 193
References......Page 194
INTRODUCTION......Page 200
MECHANISMS OF ANTIBACTERIAL RESISTANCE IN BACTERIA......Page 201
REVIEW OF THE CHALLENGES OF ANTIMICROBIAL RESISTANCE IN GRAM-NEGATIVE BACTERIA......Page 203
HERBAL EXTRACTS ARE A PRICELESS SOURCE OF ANTIMICROBIALS......Page 205
References......Page 206
INTRODUCTION......Page 210
ANIMAL HEALTH AND MULTIDRUG RESISTANCE IN PRODUCTION ANIMALS......Page 211
ANTIBIOTIC GROWTH PROMOTERS......Page 212
THERAPEUTIC EFFICACY OF PLANT EXTRACTS......Page 214
CONCLUSIONS......Page 218
References......Page 219
INTRODUCTION......Page 224
BACTERIA WITH CLINICAL IMPORTANCE......Page 226
ESSENTIAL OILS FROM THE ASTERACEAE FAMILY......Page 228
CONCLUSIONS AND FUTURE PROSPECTS......Page 237
References......Page 238
INTRODUCTION......Page 242
THE BURDEN OF MULTIDRUG RESISTANCE AND EMERGING INFECTIOUS DISEASES......Page 243
TRADITIONAL AFRICAN MEDICINE......Page 244
SUB-SAHARAN AFRICAN BIODIVERSITY IN THE FIGHT AGAINST INFECTIOUS DISEASES......Page 245
CONCLUSIONS AND FUTURE PERSPECTIVES......Page 251
References......Page 252
RESISTANCE MECHANISMS......Page 256
PLANTS WITH ANTITUMOR ACTIVITY AGAINST MULTIDRUG-RESISTANT CELLS......Page 257
QUALEA SPECIES AND THEIR MEDICAL APPLICATIONS......Page 259
ANTITUMOR ACTIVITY OF QUALEA GRANDIFLORA AND QUALEA MULTIFLORA......Page 260
References......Page 262
INTRODUCTION......Page 264
PLANT EXTRACTS WITH ANTIHERPETIC ACTIVITY......Page 266
ANTIHERPETIC ACTIVITY OF PLANT ESSENTIAL OILS......Page 269
REVIEW CRITERIA......Page 275
References......Page 276
Index......Page 280