Excitotoxins: Proceedings of an International Symposium held at The Wenner-Gren Center, Stockholm, August 26–27, 1982

Front Matter....Pages i-xii
Front Matter....Pages 1-1
Identification of Excitatory Amino Acid Pathways in the Mammalian Nervous System....Pages 3-18
Electrophysiological Actions of Kainate and Other Excitatory Amino Acids, and the Structure of Their Receptors....Pages 19-32
Two Types of Excitatory Amino Acid Responses in the Cat Caudate Nucleus....Pages 33-42
Recent Advances in the Pharmacology of Excitatory Amino Acids in the Mammalian Central Nervous System....Pages 43-54
Alteration by Kainate of Energy Stores and Neuronal-Glial Metabolism of Glutamate In Vitro....Pages 55-65
Receptors for Excitotoxins....Pages 66-81
Excitotoxins: An Overview....Pages 82-96
Front Matter....Pages 97-97
Neuronal Degeneration After Intracerebral Injections of Excitotoxins. A Histological Analysis of Kainic Acid, Ibotenic Acid and Quinolinic Acid Lesions in the Rat Brain....Pages 99-111
Kainic Acid: Insights Into Its Receptor-Mediated Neurotoxic Mechanisms....Pages 112-121
The Neurodegenerative Properties Of Intracerebral Quinolinic Acid And Its Structural Analog Cis-2,3-Piperidine Dicarboxylic Acid....Pages 122-137
Studies On Excitatory Amino Acid Receptors And Their Interactions And Regulation Of Pre- And Postsynaptic Dopaminergic Mechanism In The Rat Telencephalon....Pages 138-156
Electrophysiological And Pharmacological Studies On Kainic Acid-Induced Neuronal Activation....Pages 157-169
An Analysis Of Bioelectrical Phenomena Evoked By Microiontophoretically Applied Excitotoxic Amino-Acids In The Feline Spinal Cord....Pages 170-183
The Role Of Seizures In Kainic Acid Induced Brain Damage....Pages 184-198
Excitatory Amino Acid Transmitters In Cerebellum And Optic Tectum....Pages 199-206
Mechanisms Of Excitotoxins Examined In Organotypic Cultures Of Rat Central Nervous System....Pages 207-219
Front Matter....Pages 221-221
Ibotenate as a Tool in Neurobiology. Studies on Dopaminergic and Cholecystokinin Immunoreactive Neurons after Ibotenate Induced Lesions....Pages 223-238
Characterization Of Striatal Ibotenate Lesions And Of 6—Hydroxydopamine Induced Nigral Lesions By Morphometric And Densitometric Approaches....Pages 239-250
Effect Of Ibotenic Acid Stereotactically Injected Into Striatum Or Hippocampus On Local Blood Flow And Glucose Utilization In Rats....Pages 251-255
Synaptic Rearrangements In The Kainic Acid Model Of Ammon’s Horn Sclerosis....Pages 256-270
Front Matter....Pages 221-221
On The Problem Of Distant Lesions In Behavioual Studies Utilizing Kainic Acid....Pages 271-279
Kainic Acid Injections Into The Rat Neostratum: Effects On Learning And Exploration....Pages 280-294
Effects Of Neurotoxic Excitatory Amino Acids On Neuroendocrine Regulation....Pages 295-305
Front Matter....Pages 307-307
Adverse Reactions In Humans Thought To Be Related To Ingestion Of Elevated Levels Of Free Monosodium Glutamate (Msg) (Chinese Restaurant Syndrome And Other Reactions)....Pages 309-330
Temporal Lobe Epilepsy, Excitotoxins And The Mechanism Of Selective Neuronal Loss....Pages 331-342
Huntington’s Disease: Anti-Neurotoxic Therapeutic Strategies....Pages 343-353
Excitotoxicity In Aging And Dementia....Pages 354-362
Back Matter....Pages 363-363