Ethical Issues in HIV Vaccine Trials

Front Matter....Pages i-xv
Introduction....Pages 1-12
Where Stands the Pandemic Now?....Pages 13-23
It’s Not Just Another Disease....Pages 24-28
Will it Ever Slow Down?....Pages 29-43
Is a Vaccine Possible?....Pages 44-47
The Human Immunodeficiency Virus....Pages 48-56
How the Immune System Works....Pages 57-59
How Vaccines Work....Pages 60-71
Human Trials....Pages 72-76
Criteria of Effectiveness....Pages 77-93
Ethical Principles....Pages 94-96
Real Risks....Pages 97-141
Whom Do You Want for Volunteers?....Pages 142-147
Compensating Volunteers for Injury....Pages 148-151
Informed Consent (1)....Pages 152-155
Assessing Comprehension....Pages 156-160
Informed Consent (2)....Pages 161-165
Ethics Review Committees....Pages 166-170
Protecting Individual Subjects....Pages 171-181
Proxy Consent?....Pages 182-183
Undue Inducement....Pages 184-186
Motivations to Volunteer....Pages 187-193
Still More Questions....Pages 194-202
Data from Unethical Experiments?....Pages 203-204
The Great Simple Solution....Pages 205-208
Thesis/Antithesis: Synthesis?....Pages 209-210
Smallpox and Guinea Worm Disease as Metaphors....Pages 211-215
So …....Pages 216-217
Back Matter....Pages 218-249