Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care

Front Matter....Pages i-xxii
Front Matter....Pages 1-1
Pharmacokinetics and Pharmacodynamics of Anesthetics....Pages 3-47
A Review of Mechanisms of Inhalational Anesthetic Agents....Pages 49-60
Pharmacokinetics, Pharmacodynamics, and Physical Properties of Inhalational Agents....Pages 61-71
Principles of Total Intravenous Anesthesia....Pages 73-86
Perioperative Considerations in Pharmacology....Pages 87-99
Front Matter....Pages 101-101
Anesthetic Induction Agents....Pages 103-111
Analgesics: Opiate Agonists, Mixed Agonists/Antagonists, and Antagonists for Acute Pain Management....Pages 113-123
Analgesics: Opioids for Chronic Pain Management and Surgical Considerations....Pages 125-145
Nonopioid Analgesic and Adjunct Drugs....Pages 147-165
Benzodiazepines and Muscle Relaxants....Pages 167-178
Pharmacology of Local Anesthetics....Pages 179-194
Neuromuscular Blockers....Pages 195-204
Reversal Agents....Pages 205-218
Drugs Acting on the Autonomic Nervous System....Pages 219-233
Antihypertensives, Diuretics, and Antidysrhythmics....Pages 235-256
Peripheral Vasodilators....Pages 257-273
Nitric Oxide and Pulmonary Vasodilators....Pages 275-293
Asthma and COPD Agents....Pages 295-312
Hormones, Part 1: Thyroid and Corticosteroid Hormones....Pages 313-325
Hormones Part 2: Insulin and Other Glucose-Controlling Medications....Pages 327-343
Front Matter....Pages 101-101
Antacids, Gastrointestinal Prokinetics, and Proton Pump Inhibitors....Pages 345-363
Histamine Modulators....Pages 365-379
Central Nervous System Stimulants....Pages 381-396
Anticoagulant Drugs....Pages 397-413
Hemostatic Agents....Pages 415-420
Blood, Blood Products, and Substitutes....Pages 421-432
Antipyretics: Acetaminophen, Arachidonic Acid Agents, and COX1 and COX2 Inhibitors....Pages 433-443
Antiemetic Agents....Pages 445-451
Antiepileptic Agents....Pages 453-483
Neuropharmacologic Agents for Neurologic Conditions....Pages 485-502
Chemotherapeutic Agents....Pages 503-523
Antimicrobial Agents....Pages 525-547
Herbal Medications and Vitamin Supplements....Pages 549-562
Minerals and Electrolytes....Pages 563-572
Disinfection Agents and Antiseptics....Pages 573-580
Psychopharmacologic Agents and Psychiatric Drug Considerations....Pages 581-594
Cocaine, Methamphetamine, MDMA, and Heroin....Pages 595-605
Front Matter....Pages 607-607
Cardiac Surgery....Pages 609-643
The Intensive Care Unit....Pages 645-659
Enteral and Parenteral Nutrition....Pages 661-675
Front Matter....Pages 607-607
Obstetrics....Pages 677-696
Pediatrics....Pages 697-705
Neurologic Surgery....Pages 707-717
Liver Disease and Liver Transplantation....Pages 719-737
Front Matter....Pages 739-739
Black Box FDA Warnings and Legal Implications....Pages 741-751
Drug-Induced QT Prolongation....Pages 753-766
Drugs and Cancer Propagation....Pages 767-781
Lipid-Lowering Agents....Pages 783-796
Serotonin Syndrome....Pages 797-807
Front Matter....Pages 809-809
Novel Psychoactive Substances: Synthetic Cathinones and Cannabinoid Receptor Agonists....Pages 811-818
New Vistas in Anesthetics, IV Induction Agents....Pages 819-826
New Vistas in Neuromuscular Blockers....Pages 827-835
Patient-Controlled Analgesia: The Importance of Effector Site Pharmacokinetics....Pages 837-846
Understanding Anesthesia-Induced Memory Loss....Pages 847-858
Novel Targets of Current Analgesic Drug Development....Pages 859-873
Back Matter....Pages 875-904