Enzymes as Catalysts in Organic Synthesis

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Baker’s Yeast Mediated Preparation of Carbohydrate-Like Chiral Synthons....Pages 3-17
Alcohol Dehydrogenase Catalysed Oxidoreduction Reactions in Organic Chemistry....Pages 19-34
On The Use of Viologen Dyes for Stereospecific Bioreduction....Pages 35-44
Approaches to Chiral Building Blocks for Natural Product Synthesis....Pages 45-54
Use of Microorganisms for the Resolution of Synthetically Useful Bicyclo[3.2.0]Hept-2-En-6-Ones....Pages 55-75
The Scope of Biocatalysts in Organic Chemical Processing....Pages 77-95
Enantioselective Synthesis of Biologically Active Cyclopentanoids Via Enzyme Catalysed Asymmetric Reactions....Pages 97-122
Creation of Novel Chiral Synthons with Pig Liver Esterase: Application to Natural Product Synthesis and the Substrate Recognition....Pages 123-142
Application of Microbial Transformations in the Total Synthesis of Natural Products....Pages 143-169
Approaches to Chiral Building Blocks for Natural Products Synthesis....Pages 171-176
Synthesis of Enantiomerically Pure Unnatural Compounds Via Non-Biomimetic Homoaldol Reactions....Pages 177-198
Aldolases as Catalysts in Organic Synthesis....Pages 199-216
Immobilised Redox Enzymes and Their Use as Catalysts for Fine Chemical Synthesis....Pages 217-232
Applications of Microbes and Microbial Enzymes in Environmental Control and Organic Synthesis....Pages 233-250
Synthesis of Chirally Labelled Substrates Using Enzymes....Pages 251-262
Synthesis of L-Amino Acids by Isolated Enzymes and Microorganisms....Pages 263-284
Development of an Enzyme Reactor for Food Chemistry....Pages 285-301
Preparation and Properties of Semisynthetic Flavoenzymes....Pages 303-310
The Study and Redesign of Enzymes by Protein Engineering....Pages 311-323
Evolutionary Guidance and the Engineering of Enzymes....Pages 325-340
Front Matter....Pages 341-341
Baker’S Yeast Mediated Synthesis of Protected α-Hydroxyaldehydes....Pages 343-345
Enantioselective Ple-Catalyzed Hydrolysis of Meso-Dimethyl Tetrahydrophthalate on a 100 Mole Scale — Protection of the Enzyme by Addition of Bovine Serum Albumin....Pages 347-347
Enantio- and Diastereoselectivity of Microsomal Epoxide Hydrolase: Potential Applications to the Preparation of Non-Racemic Epoxides and Diols....Pages 349-354
Efficient Enzymic Production of Enantiomerically Pure Amino Acids....Pages 355-360
Biohydroxylation of Non Activated Carbon Atoms. A Model for the Hydroxylation Site of the Fungus Beauveria Sulfurescens....Pages 361-370
“Sterols Bioconversions in Systems with an Organic Phase”....Pages 371-382
Second-Generation Biocatalysis....Pages 383-390
Round-Table Discussions....Pages 391-401
Back Matter....Pages 403-421