Enzymatic Bioelectrocatalysis

Preface
Acknowledgments
Contents
Abbreviations and Symbols
	Enzyme
	Redox Center
	Chemical
	Electrode
	Others
	Symbols
	Greek Symbols
1 Redox Proteins and Bioelectrocatalysis
	1.1 Oxidoreductases [1, 2]
	1.2 Redox Components
		1.2.1 NAD(P)(H) [1, 5]
		1.2.2 Flavins [1, 6, 7]
		1.2.3 Quinones [7, 12]
		1.2.4 Hemes [1, 30]
		1.2.5 Ion-Sulfur Clusters [1, 7]
		1.2.6 Copper [33]
		1.2.7 Nickel [39]
		1.2.8 Molybdenum [41]
		1.2.9 Others
	1.3 Bioelectrocatalysis
	References
2 MET-Type Bioelectrocatalysis
	2.1 Reaction-Layer Approximation in a Homogeneous System
	2.2 Selection of Mediators
	2.3 Mathematical Model in Immobilized Layers
	2.4 Serial Resistance Model for Steady-State Response in MET-Type Bioelectrocatalysis
	2.5 Redox Mediators
	2.6 Immobilization of Enzymes and Mediators
		2.6.1 Bifunctional Reagents
		2.6.2 Redox Polymers
	2.7 Electrode Materials
	References
3 Fundamentals of DET-Type Bioelectrocatalysis
	3.1 History of DET-Type Bioelectrocatalysis
	3.2 Theory of Steady-State Catalytic Current
	3.3 Random Orientation Model of Enzymes
	3.4 Data Analysis of the Steady-State DET-Type Bioelectrocatalytic Waves
	References
4 Characteristic Properties of Redox Enzymes as Electrocatalysts
	4.1 Introduction
	4.2 Surface-Area Effect and Curvature Effects (or Cage Effect) on Mesoporous Electrodes
	4.3 Interfacial Electrode Kinetics on Microporous Electrodes
	4.4 The Control of the Orientation of Adsorbed Enzymes by Surface Modification of Electrodes
	4.5 DET-Type Bi-Way Bioelectrocatalysis
	References
5 Protein-Engineering Approach for Improvement of DET-Type Bioelectrocatalytic Performance
	5.1 Motivation of Protein-Engineering
	5.2 Enzyme Trimming
	5.3 Site-Directed Mutation
	5.4 Protein Surface Modification
	References
6 Applications to Biosensors
	6.1 Introduction
	6.2 Selectivity of Electrochemical Biosensors
	6.3 Electrodes for Amperometric Biosensing
	6.4 Mass-Transfer-Controlled Amperometric Biosensing
	6.5 Potentiometric Coulometry
		6.5.1 Bienzyme Biosensing
	References
7 Applications to Biofuel Cells and Bioreactors
	7.1 From Bioelectrocatalysis to Biofuel Cells and Bioreactors
	7.2 Biofuel Cell
	7.3 Photobioelectrochemical Water Splitting
	7.4 Bioelectrochemical/Biochemical Hydrogen/C1 Economy
	References
Conclusions and Outlooks