Energy Metabolism and Obesity: Research and Clinical Applications

Front Matter....Pages I-XI
Molecular Physiology of Monogenic and Syndromic Obesities in Humans....Pages 1-22
Leptin Signaling In the Brain....Pages 23-43
Inactivating Melanocortin 4 Receptor Mutations and Human Obesity....Pages 45-58
The Role of Central Melanocortins in Cachexia....Pages 59-68
The Efferent Arm of the Energy Balance Regulatory Pathway: Neuroendocrinology and Pathology....Pages 69-85
Adiponectin: A Multifunctional Adipokine....Pages 87-105
The Role of the Gastrointestinal Hormones Ghrelin, Peptide YY, and Glucagon-like Peptide-1 in the Regulation of Energy Balance....Pages 107-123
The Role of Growth Hormone Secretagogues and Ghrelin in Feeding and Body Composition....Pages 125-154
Interaction Between Physical Activity and Genetic Factors in Complex Metabolic Disease....Pages 155-173
11β-Hydroxysteroid Dehydrogenase Type 1 and Obesity....Pages 175-196
Prader-Willi Syndrome: A Model of Disordered Energy Homeostasis....Pages 197-222
Antipsychotic Medication–Induced Weight Gain and Risk for Diabetes and Cardiovascular Disease....Pages 223-245
Treatment of Insulin Resistance in Youth: The Role of Metformin....Pages 247-267
The Surgical Approach to Morbid Obesity....Pages 269-296
Back Matter....Pages 297-302