Endocrine Disorders in Thalassemia: Physiopathological and Therapeutical Aspects

Front Matter....Pages I-XVII
Front Matter....Pages 1-1
Spontaneous Growth Hormone (GH) Secretion and Results of Therapy with GH in Thalassemic Patients....Pages 3-5
Plasma Growth Hormone-Binding Protein and Liver Receptor in Thalassemic Patients....Pages 7-10
Short-term Follow-up Study of Thyroid Function in Polytransfused Thalassemic Patients....Pages 11-17
Spermatogenesis in Patients with β-Thalassaemia major and intermedia....Pages 19-24
Long-term Follow-up of Hypothalamic-Pituitary Axis in Thalassaemic Patients with Secondary Amenorrhoea....Pages 25-38
Abnormal Bone Metabolism in Thalassemia....Pages 39-46
Bone Mineral Content by Single- and Dual-Photon Absorptiometry in Thalassemic Patients....Pages 47-51
Osteopenia in Thalassemic Patients with Primary and Secondary Amenorrhea....Pages 53-57
Imaging, Ultrastructural Aspects, and Trace Elements in the Thalassemic Condrodystrophy....Pages 59-64
Glucose Intolerance and Diabetes in Thalassaemia major....Pages 65-67
Pancreatic beta-Cell Function Before and After Bone Marrow Transplantation for Thalassemia....Pages 69-72
A Multicenter Study on Endocrine Disorders in Thalassemia — Introduction....Pages 73-74
Endocrine Pathology in Thalassemia....Pages 75-82
Endocrine Complications in Cyprian Thalassemic Patients....Pages 83-89
Thalassemia and Endocrinopathies: Multicenter Study of 3092 Patients....Pages 91-93
Front Matter....Pages 95-95
Growth in Homozygous β-Thalassemic Patients....Pages 97-101
Relationship Between GH Response to Stimuli, Levels of IGF-1, and Final Height....Pages 103-105
Growth Hormone Secretion in Thalassemic Patients....Pages 107-109
Binding of Insulin-like Growth Factor-1 to Erythrocytes in Children with Thalassemia....Pages 111-115
Evaluation of Thyroid Function in Thalassemic Patients Undergoing Long-term Blood Transfusion and Iron-Chelation Therapy....Pages 117-120
Front Matter....Pages 95-95
Pituitary-Thyroid Function in Children with β-Thalassemia major....Pages 121-124
Thyroid Function in Thalassemia major....Pages 125-129
Pituitary-Gonadal Response to Short-term Pulsatile Luteinizing Hormone-Releasing Hormone Administration in Young Thalassemic Patients....Pages 131-135
Long-term Gonadotropin Administration to Restore Gonadal Function in Male Thalassemics....Pages 137-139
Pubertal Development in Female Thalassemics....Pages 141-143
The Pituitary-Thyroid-Gonadal Axis in Saudi β-Thalassaemia Patients....Pages 145-147
Insulin-Dependent Diabetes mellitus in a Group of Young People with beta-Thalassemia major....Pages 149-152
A Transverse and Longitudinal Study of Pancreatic Function and Glucose Tolerance in Thalassemic Patients....Pages 153-155
β-Cell Glucose Non-sensing in Patients with Thalassemia major and Glucose Intolerance....Pages 157-160
Secondary Diabetes mellitus in Thalassemic Patients....Pages 161-165
Back Matter....Pages 167-168