Drugs Affecting Lipid Metabolism: Proceedings of the Third International Symposium on Drugs Affecting Lipid Metabolism, held in Milan, Italy, September 9–11, 1968

Front Matter....Pages i-xii
Opening Remarks....Pages 1-3
The Regulation of Cyclic AMP and Lipolysis in Adipose Tissue by Hormones and Other Agents....Pages 5-23
Nervous and Pharmacological Regulation of Vascular Reactions in Adipose Tissue....Pages 25-34
Evidence That the Rise in Temperature Produced by d -Amphetamine is Caused by a Peripheral Action of the Drug....Pages 35-43
Effects of Adrenergic Blocking Agents on FFA Mobilization....Pages 45-61
Adenosine 3′,5′-Monophosphate and Regulation of Lipolysis in Rat Adipose Tissue....Pages 63-74
Factors Modifying the Effect of Prostaglandin E 1 on Lipolysis in Adipose Tissue....Pages 75-84
Pyridines Affecting FFA Mobilization In Vivo ....Pages 85-92
Effects of 5-Methylpyrazole-3-Carboxylic Acid, U-19425, on FFA Mobilization....Pages 93-103
Effect of 5-Methylpyrazole-3-Carboxylic Acid (MPCA) on Fat Mobilization, Ketogenesis and Glucose Metabolism during Exercise in Man....Pages 105-115
Transport-Inducing Antibiotics (Gramicidin and Valinomycin) as Inhibitors of Catecholamine-Stimulated Lipolysis In Vitro....Pages 117-124
Studies of the Mechanism of Prevention of Fatty Livers by the Administration of Adenosine Triphosphate....Pages 125-134
Action of Norepinephrine and Propranolol on the Turnover Rate of Free Fatty Acids and the Esterification Rate of Free Fatty Acids to Plasma Triglycerides in Man....Pages 135-144
 In Vivo and In Vitro Studies of Plasma Post-Heparin Lipolytic Activity in Subjects with Hyperchylomicronemia (Fat-Induced Lipemia)....Pages 145-159
Isolated Fat Cells: Morphology and Possible Role of Released Lipoprotein Lipase in Deposition of Lipoprotein Fatty Acid....Pages 161-183
Regulatory Factors in Ketogenesis and in the Metabolism of Triglycerides by Liver....Pages 185-200
Correlation between the Effect of Drugs on Plasma Free Fatty Acids and on Tissue Triglycerides....Pages 201-211
The Effects of 5-Methylpyrazole-3-Carboxylic Acid (U-19,425) and Nicotinic Acid (NA) on Free Fatty Acids (FFA), Triglycerides (TG) and Cholesterol in Man....Pages 213-226
Studies with 5-(3-Pyridyl)Tetrazole, a Long-Acting Lipolysis Inhibitor....Pages 227-238
Influence of Lipolytic and Antilipolytic Agents on Synthesis of Adipose Tissue Lipoprotein Lipase....Pages 239-248
Effects of Estradiol-17β and Progesterone on Experimental Mammary Carcinoma Lipid....Pages 249-259
Some Factors Affecting Release of Clearing Factor Lipase from Isolated Perfused Rat Heart....Pages 261-278
Carnitine Regulation of Fatty Acid Metabolism in Heart....Pages 279-293
Neurotoxic Organophosphorus Esters and Lipid Metabolism....Pages 295-306
The Typing of Hyperlipoproteinemia: A Progress Report (1968)....Pages 307-325
The Effect of Nicotinic Acid Treatment on the Chemical Composition of Plasma Lipoprotein Classes in Man....Pages 327-338
A Primary Prevention Trial Using Clofibrate (Atromid-S)....Pages 339-344
Environmental Effects on the Structure of Human Serum High Density Lipoprotein and Its Apoprotein....Pages 345-354
The Effects of Trans Isomerized Trilinolein on Plasma Lipids of Man....Pages 355-364
Selective Inhibition of Hepatic but Not Intestinal β-Lipoprotein Production and Triglyceride Transport in Rats Given Orotic Acid....Pages 365-375
The Efficacy of Clofibrate (CPIB) in Familial Hyperlipoproteinemias....Pages 377-387
The Effect of Chlorophenoxyisobutyrate (CPIB) in Various Types of Primary Hyperlipidemia....Pages 389-394
Interrelationship of Chlorophenoxyisobutyrate, Ubiquinone, and Cholesterol....Pages 395-403
The U.S. Veterans Administration Cardiology Drug-Lipid Study: An Interim Report....Pages 405-420
Effect of Drugs on Bile Acid Metabolism....Pages 421-441
Factors Influencing Cholesterol 7 α -Hydroxylase Activity in the Rat Liver....Pages 443-456
Effect of Hypocholesteremic Agents on an Experimental Brain Tumor in Mice....Pages 457-471
Butyrophenones as Inhibitors of Cholesterol Biosynthesis....Pages 473-482
Evaluation of Phenolic Ethers as Hypolipidaemic Agents: Effects of CIBA 13,437-SU....Pages 483-489
Linoleamides: A New Class of Hypocholesteremics....Pages 491-499
The Influence of Anovulatory Compounds on Cholesterol Metabolism....Pages 501-510
The Effect of Hypoglycemic Agents on Cholesterol Biosynthesis....Pages 511-520
Hypophyseal Mediation of Estrogen-Induced Hypocholesterolemia....Pages 521-529
Drugs Affecting the Enterohepatic Circulation of Cholesterol....Pages 531-542
Oxidation of Cholesterol by Rat Liver Mitochondria: Influence of Ethyl α -p-Chlorophenoxyisobutyrate....Pages 543-548
Cholesterol-Lowering Effect of Sulfaguanidine in Mice and Rats....Pages 549-557
Use of High-Efficiency Nonpolar Columns in Systematic Separation and Identification of Steroids by Combined TLC-GLC Method of Analysis....Pages 559-581
The Analysis of Blood Lipids by Chromatography and Infrared Spectrophotometry....Pages 583-596
The Characterization of Phospholipids by Gas Phase Analytical Methods....Pages 597-608
Ether-Linked Lipids in Neoplasms of Man and Animals: Methods of Measurement and the Occurrence and Nature of the Alkyl and Alk-1-Enyl Moieties....Pages 609-620
Lipoprotein Patterns in Primary Hyperlipidemias, as Registered by Agarose Gel Electrophoresis....Pages 621-628
Lipids Affecting Drug Metabolism and Cellular Functions....Pages 629-638
New Approaches to the Fractionation of Lipids....Pages 639-650
Back Matter....Pages 651-681