DNA — Technology and Its Forensic Application

Front Matter....Pages I-XI
Front Matter....Pages 1-1
Principles and Recent Advances in DNA Fingerprinting....Pages 3-19
DNA Fingerprinting as a Tool of Paternity Testing in Germany....Pages 20-32
Genetic Typing of Biological Evidence Using the Polymerase Chain Reaction....Pages 33-40
A Critical Review of the Forensic Application of DNA Technology....Pages 41-49
DNA Methylation: A Defense Mechanism Against the Expression of Foreign DNA?....Pages 50-58
Juristische Aspekte der forensischen DNA-Analyse....Pages 59-67
Front Matter....Pages 69-69
Research Regarding the Polymerase Chain Reaction for Forensic Utility — HLA-DQα Locus and AMP-FLPs....Pages 71-78
DNA Typing Using PCR Amplified Fragments in the HLA Class I Region....Pages 79-84
PCR-Typing of the Human HLA-DQα Locus: Population Genetics and Application in Forensic Casework....Pages 85-91
DNA Amplification (PCR) of Several Hypervariable Loci in Disputed Paternity Cases....Pages 92-95
Amplification of a Highly Polymorphic VNTR Segment, Localized on the Ha-Ras Gene by PCR....Pages 96-100
Front Matter....Pages 101-101
Reliability of Restriction Enzyme Digestions of Genomic DNA for the Generation of DNA Fingerprints....Pages 103-108
Concept for a More Precise Definition of the Polymorphism YNH24....Pages 109-115
Evaluation of Variable Number of Tandem Repeat (VNTR) Alleles in Mother-Child Combinations....Pages 116-120
A Proposed Combination of Single Locus Probes for Multiple Rehybridization....Pages 121-127
DNA-Profiles with HVR-Probes — Allele Frequencies of HinfI-RFLPs Using pHINS310, pMUC7 and pMR24/1 in a Population Sample from Hannover and Lower Saxony....Pages 128-133
Analysis of Allele Frequencies of Two Polymorphic Loci in a North-East Italian Population....Pages 134-140
Digoxigenin-DNA Probes for Detecting Human VNTR Polymorphism....Pages 141-144
Front Matter....Pages 145-145
The Application of Four Single Locus Probes in Cases of Disputed Paternity....Pages 147-152
The Practical Significance of Human Genetic RFLP-Systems in Paternity Testing....Pages 153-156
Front Matter....Pages 145-145
Individual Diagnostics by DNA Fingerprinting....Pages 157-159
Paternity Analysis in a Deficient Family by DNA Profiling (Single-Locus and Multi-Locus Probes)....Pages 160-164
Paternity Tests in 10–12 Weeks Old Fetuses by Means of Single-Locus-DNA-Polymorphisms....Pages 165-169
DNA Fingerprinting for the Protection of Endangered Species....Pages 170-171
Front Matter....Pages 173-173
Treatment of Bloodstains for Simultaneous Application of Serological and DNA Typing Methods....Pages 175-180
DNA Extraction and RFLP Analysis of Bloodstains on a Variety of Textiles — Investigation of Various Extraction Procedures....Pages 181-186
Stability of DNA in Brain Cortex After Long Post Mortem Periods....Pages 187-191
The Identification of a Charred Body by Oligonucleotide Fingerprinting with the (GTG) 5 Probe....Pages 192-195
Front Matter....Pages 197-197
Biostatistical Evaluation of Evidence from Single Locus Hypervariable DNA Probes: Tests of Independence of Loci....Pages 199-202
MLP and SLP Band Patterns and Probabilities of Identity....Pages 203-207
Efficiency of Multilocus Probes in Mother-Child-Putative Father Cases....Pages 208-211
The Proposal of Evett et al. for Paternity Calculations in Normal Trio Cases Using MLP Profiles and the Freiburg Model of a Multiple Diallelism: A Comparison....Pages 212-220
A Contribution to the Computer-Aided Analysis of DNA Fingerprint Patterns....Pages 221-225