DNA Synthesis: Present and Future

Front Matter....Pages i-xiv
Control of DNA Replication in Bacteria....Pages 1-26
Map Position of the Replication Origin of the E.coli K12 Chromosome....Pages 27-31
An Approach to the Isolation of the Replication Origin of Bacillus Subtilis ....Pages 33-39
Stability of Origin-RNA and its Implications on the Structure of the Origin of Replication in E . coli ....Pages 41-48
The Genetics of E.Coli DNA Replication....Pages 49-70
Characterization of Chromosomal Replication in a dna A Mutant....Pages 71-83
Genetic and Physiological Properties of an Escherichia Coli Strain Carrying the dnaA Mutation T46....Pages 85-99
The Function of RNA Polymerase and dnaA in the Intitiation of Chromosome Replication in Escherichia coli and Salmonella Typhimurium ....Pages 101-111
Stabilized Initiation Activity of DNA Replication in an Sdr c Mutant of Escherichia Coli ....Pages 113-120
Replication of Bacteriophage Mu: Direction and Possible Location of the Origin....Pages 121-126
Control of the Initiation of Lambda Replication, oop , lit and Repressor Establishment RNA Synthesis....Pages 127-142
Control of Initiation of DNA Replication in Mammalian Cells....Pages 143-159
Developmental Considerations of Eukaryotic DNA Replication and Replicon Size....Pages 161-174
The Organization of DNA Replication in a Mammalian Cell Line....Pages 175-188
An Unusual Structure Implicated in Initiation of DNA Synthesis....Pages 189-201
Inhibition of DNA Synthesis by 1-β-D-Arabinofuranosylcytosine: Differential Effect on Chain Initiation and Elongation in Human Lymphoblasts....Pages 203-217
Thymidine Metabolism in Bacteria (and “How, or How Not, to Label DNA”)....Pages 219-253
Deoxyribonucleoside Triphosphates and DNA Polymerase in Bacteriophage PBS1-Infected Bacillus Subtilis ....Pages 255-266
 In Vivo Synthesis and Properties of Uracil-Containing DNA....Pages 267-279
Excision Repair of Uracil in DNA and Its Contribution to the Pool of Okazaki Fragments....Pages 281-298
DNA Replication Intermediates in Escherichia Coli ....Pages 299-308
Size Distribution of Short Chain DNA in Two Strains of Escherichia Coli ....Pages 309-319
Evidence for the Absence of Triphosphate Termini From the 5′ Ends of Newly Synthesized E.Coli DNA Molecules....Pages 321-332
On the Possible Direct Conversion of RNA to DNA....Pages 333-346
Some Aspects of DNA Strand Separation....Pages 347-366
Multiple Interactions of a DNA Binding Protein, Gene- 32 Protein of Phage T4, during DNA Replication and Recombination....Pages 367-380
Interaction of Protein HD from E.Coli with Nucleic Acids....Pages 381-385
A Putative DNA Gyrase Mutant of E.Coli ....Pages 387-395
The Role of ATP in E.Coli Chromosome Replication....Pages 397-407
Nucleic Acid Binding Glycoproteins Which Solubilize Deoxyribonucleic Acid in Dilute Acid: Species Distribution and Possible Role in DNA Condensation....Pages 409-422
ATP Dependent Deoxyribonuclease of Bacillus Subtilis ; Subunit Structure and Substrate Specificity Of DNA Dependent -ATPase Activity....Pages 423-429
Pl Transduction Frequencies: A Clue to Chromosome Structure ?....Pages 431-438
Bacterial Nucleoid Structure After Inhibition of DNA Replication: the Role of RNA Synthesis....Pages 439-445
Specific Properties of the End Groups of rDNA from Tetrahymena ....Pages 447-453
Recombinational Mapping of the polA Locus of Escherichia Coli K12: Genetic Fine Structure....Pages 455-466
DNA Polymerase III of B.subtilis : Characterization of the Binding Site for Arylhydrazinopyrimidine Inhibitors....Pages 467-477
DNA Proof-Reading by a Eukaryotic DNA Polymerase....Pages 479-486
The Three DNA Polymerases of Animal Cells: Properties and Functions....Pages 487-515
Structure and Catalytic Properties of Human DNA Polymerases α and β....Pages 517-558
Properties and Interactions of DNA Polymerase α, DNA Polymerase β and a DNA Binding Protein of Regenerating Rat Liver....Pages 559-583
DNA Polymerases of Sea Urchin Embryos....Pages 585-596
Identity between Nuclear and Mitochondrial DNA Polymerases γ from Chick Embryo....Pages 597-603
Neurons as a Model System for In Vivo Studies of the Possible Function of DNA Polymerases in DNA Replication and Repair Synthesis During Development....Pages 605-612
DNA Polymerase in Chromatin....Pages 613-628
DNA Polymerase and the Onset of DNA Synthesis in Wheat Embryos....Pages 629-639
Effect of SV4O Infection on DNA Polymerase Activity in Monkey Cells....Pages 641-654
Characterization of Bacteriophage T7-Induced DNA Primase....Pages 655-667
Suppression of E.coli dnaB Mutants by Prophage Pl bac : A Biochemical Approach....Pages 669-682
Two Replication Functions in Phage Pl: ban , an Analog of dnaB , and bof , Involved in the Control of Replication....Pages 683-692
The Present Status of ØX174 DNA Replication in Vivo....Pages 693-704
Enzymatic Replication of DNA in E.Coli Probed by Small Phages....Pages 705-728
The dnaG Gene Product of Escherichia Coli : Characterization of the Catalytic Activity....Pages 729-738
G4 and ST-1 DNA Synthesis In Vitro ....Pages 739-749
Plasmid Replication....Pages 751-772
Copy Number Control Mutants of the R Plasmid R1 in Escherichia Coli ....Pages 773-786
Determination of Origin and Direction of Replication of Large Plasmids of E.Coli by Two Electron Microscopic Techniques....Pages 787-795
Replication of Colicin El Plasmid DNA In Vitro ....Pages 797-826
A Two-Stage Mechanism of Plasmid DNA Replication....Pages 827-838
Adenoviruses — Model for DNA Replication in Mammalian Cells — Role of Viral Proteins in Viral DNA Replication....Pages 839-867
Function of an Early DNA Binding Protein in the Replication of Adenovirus DNA....Pages 869-883
Sequence Selectivity in the Integration of Adenovirus Type 2 DNA in Productively Infected Cells....Pages 885-894
DNA Repair in Human Cells: Enzymes and Mutants....Pages 895-913
Enzymes Involved in the Repair of Damaged DNA....Pages 915-965
 In Vitro Characterization of the uvrA + , uvrB + , uvrC + -Coded ATP-Dependent UV-Endonuclease from Escherichia Coli ....Pages 967-978
The recA + Gene Product of Escherichia coli , an Inducible Protein....Pages 979-987
UV Endonucleolytic Activity in Extracts from Mouse Cells....Pages 989-998
On the Mechanism of Ultraviolet-Induced Mutagenesis....Pages 999-1010
An Adaptive Response of E.coli to Low Levels of Alkylating Agent....Pages 1011-1024
Plasmid-Borne Error-Prone DNA Repair....Pages 1025-1032
DNA Synthesis in Permeable Cell Systems from Saccharomyces Cerevisiae ....Pages 1033-1053
DNA Replication in Simple Eukaryons: Identification of Replisomal Complexes in Cell Extracts of Chlamydomonas reinhartii ....Pages 1055-1068
Studies with Enzyme Complexes that Synthesize Adenovirus 2 DNA In Vitro ....Pages 1069-1092
Studies on Replicating Simian Virus 40 Chromosomes: Association with Thymidine Kinase....Pages 1093-1110
Synthesis of DNA and Poly (ADP Ribose) in Permeabilized Eukaryotic Cells....Pages 1111-1122
Effect of Xenopus Laevis Oocyte and Egg Extracts on SV40 DNA....Pages 1123-1143
Back Matter....Pages 1145-1161