Disorders of the Monocyte Macrophage System: Pathophysiological and Clinical Aspects

Front Matter....Pages I-X
Front Matter....Pages 1-1
Current View of the Mononuclear Phagocyte System....Pages 3-10
The Kinetics of Mononuclear Phagocytes in Man....Pages 11-22
Biochemical Properties of Human and Murine Mononuclear Phagocytes and Their Changes on Activation....Pages 23-30
Macrophages in the Regulation of Immunity....Pages 31-37
The Role of Macrophages as Effector Cells....Pages 39-48
The Macrophage as a Cytotoxic Effector Cell....Pages 49-57
The Role of Complement in the Function of the Monocyte — Macrophage System....Pages 59-71
Macrophage-Dependent Production of Erythropoietin and Colony-Stimulating Factor....Pages 73-78
The Relation Between Monocytes and Resident (Tissue) Macrophages....Pages 79-87
Development of Exudate-Resident Macrophages In Vivo and In Vitro....Pages 89-100
The Monocyte-Macrophage System In Granulomatous Inflammation....Pages 101-107
Macrophages in Granulomas: Histochemical Evidence Suggesting Local Control of Heterogeneous Functions....Pages 109-119
The Role of Macrophages in Storage Diseases....Pages 121-130
Interaction of Lipoproteins with Macrophages....Pages 131-136
The Role of Macrophages in Atherosclerosis....Pages 137-142
Front Matter....Pages 143-143
Acute Monocytic Leukemias....Pages 145-156
Subacute and Chronic Myelomonocytic Leukemia....Pages 157-165
Lysosomal Granules in Leukemic Monocytes and Their Relation to Maturation Stages....Pages 167-173
Characteristics and Functions of Monocytes and Promonocytes in Monocytic Leukemia....Pages 175-178
Chronic Monocytic Leukemias....Pages 179-187
Front Matter....Pages 143-143
Therapy of Acute Monoblastic Leukemia....Pages 189-194
Histiocytic Medullary Reticulosis — Neoplastic or Atypical Inflammatory Process? A Report of Two Cases with Review of the Literature....Pages 195-203
Histiocytic Medullary Reticulosis Re-visited....Pages 205-210
Therapy of Malignant Histiocytosis....Pages 211-216
Immunohistochemical Marking of Malignant Fibrous Histiocytoma and Malignant Histiocytosis....Pages 217-219
Malignant Histiocytic Disorders of the Skin....Pages 221-224
Childhood Histiocytosis X: Clinical Aspects and Therapeutic Approaches....Pages 225-229
Therapy in Pulmonary Histiocytosis X....Pages 231-237
Sinus Histiocytosis with Massive Lymphadenopathy and Epidural Involvement....Pages 239-243
Familial Lymphohistiocytosis....Pages 245-253
Concluding Remarks: The Pathology of the Monocyte-Macrophage System — Present Knowledge and Future Trends....Pages 255-256
Back Matter....Pages 257-262