Dioxins and Health

Dioxins and Health......Page 2
Copyright......Page 4
Contents......Page 6
Contributors......Page 8
Preface......Page 12
1 Overview: The Dioxin Debate......Page 16
2 Production, Distribution, and Fate of Polychlorinated Dibenzo-p-Dioxins, Dibenzofurans, and Related Organohalogens in the Environment......Page 69
3 Dioxins and Dioxinlike PCBs in Food......Page 102
4 Toxicology of Dioxins and Dioxinlike Compounds......Page 150
5 Health Risk Characterization of Dioxins and Related Compounds......Page 171
6 Pharmacokinetics of Dioxins and Related Chemicals......Page 203
7 Dose-Response Modeling for 2,3,7,8-Tetrachlorodibenzo-p-Dioxin......Page 259
8 Immunotoxicology of Dioxins and Related Chemicals......Page 311
9 Developmental and Reproductive Toxicity of Dioxins and Related Chemicals......Page 341
10 Effects of Polychlorinated Biphenyls on Neuronal Signaling......Page 444
11 Experimental Toxicology: Carcinogenesis......Page 467
12 Ah Receptor: Involvement in Toxic Responses......Page 501
13 Biochemical Responses to Dioxins: Which Genes? Which Endpoints?......Page 543
14 Evolutionary and Physiological Perspectives on Ah Receptor Function and Dioxin Toxicity ......Page 569
15 Dioxin Toxicity and Aryl Hydrocarbon Receptor Signaling in Fish......Page 613
16 Exposure Assessment: Measurement of Dioxins and Related Chemicals in Human Tissues......Page 639
17 Human Health Effects of Polychlorinated Biphenyls......Page 689
18 Epidemiological Studies on Cancer and Exposure to Dioxins and Related Compounds ......Page 739
19 Reproductive and Developmental Epidemiology of Dioxins......Page 775
20 Health Consequences of the Seveso, Italy, Accident......Page 836
21 The Yusho Rice Oil Poisoning Incident......Page 863
22 The Yucheng Rice Oil Poisoning Incident......Page 900
Index......Page 927