Diagnostic Pathology: Cytopathology second ed Dina R Mody MD, Savitri Krishnamurthy MD, Michael J. Thrall MD

Cover
Copyright
Dedications
Contributing Authors
Preface
Acknowledgments
Sections
Contents
Gynecologic Cytopathology: Overview
	Pap Test and Cervical Cancer Screening: History and Reporting Terminology
	Cytopreparation, Instrumentation, and Automated Screening in Gynecologic Cytology
	Specimen Adequacy in Cervicovaginal Cytology
Gynecologic Cytopathology: Benign and Infectious Conditions
	Normal Pap Test
	Infectious and Other Organisms in Pap Tests
	Nonneoplastic Findings, Mimics, and Artifacts
Gynecologic Cytopathology: Squamous Cell Abnormalities and Mimics
	Low-Grade Squamous Intraepithelial Lesion and Mimics
	High-Grade Squamous Intraepithelial Lesion and Mimics
	Atypical Squamous Cells of Undetermined Significance
	Atypical Squamous Cells, Cannot Rule Out High-Grade Squamous Intraepithelial Lesion
	Squamous Cell Carcinoma of Cervix, Variants and Mimics
Gynecologic Cytopathology: Glandular Cell Abnormalities and Mimics
	Endocervical Adenocarcinoma In Situ, Variants and Mimics
	Adenocarcinoma, Minimal Deviation
	Endometrial Cancers: Usual Types, Variants, and Mimics
	Atypical Glandular Cells: Endocervicals, Endometrials, and Glandulars, NOS
	Endometrial Cells in Pap Test and Glandular Cells Status Post Hysterectomy
Gynecologic Cytopathology: Extrauterine Carcinomas and Other Malignancies of Female Genital Tract
	Extrauterine Carcinomas and Presentations in Cervicovaginal Cytology
	Small Cell Neuroendocrine Carcinoma of Cervix
	Other Uncommon Malignancies in Cervicovaginal Cytology
Gynecologic Cytopathology: Molecular Testing in Gynecologic Cytology
	HPV and Other Molecular Testing in Gynecologic Cytology
Gynecologic Cytopathology: Directly Sampled Endometrial Cytology
	Directly Sampled Endometrial Cytology
Gynecologic Cytopathology: Anal Cytology
	Anal Cytology
Exfoliative Cytopathology: Respiratory Tract Including Lung FNAs
	Specimen Types in Respiratory Cytology and Adequacy Criteria
	Benign and Reactive Changes
	Pneumocystis Pneumonia and Mimics
	Fungal Organisms in Respiratory Cytology
	Parasitic Organisms in Respiratory Cytology
	Viral Infections (Cytomegalovirus, Herpesvirus, and Others)
	Mycobacteria and Other Bacterial Infections
	Sarcoidosis and Other Immune-Related Conditions
	Pulmonary Alveolar Proteinosis and Mimics
	Miscellaneous Findings Including Contaminants
	Adenocarcinoma
	Squamous Cell Carcinoma
	Small Cell Carcinoma
	Large Cell Neuroendocrine Carcinoma
	Carcinoid and Atypical Carcinoid
	Rare Benign and Low Malignant Potential Tumors
	Rare Malignant Tumors
	Pulmonary Lymphoma
Exfoliative Cytopathology: Gastrointestinal Tract
	Specimen Types in Gastrointestinal Cytology and Normal Cellular Components
	Parasitic Infections
	Viral Infections
	Esophagitis and Barrett Esophagus
	Esophageal Adenocarcinoma
	Esophageal Squamous Cell Carcinoma
	Gastritis and Intestinal Metaplasia
	Gastric Adenocarcinoma
	Gastric Lymphoma
	Ampulla/Bile Duct/Pancreatic Duct Reactive Changes
	Colorectal Adenoma/Carcinoma
	Neuroendocrine Tumor/Carcinoma
	Spindle Cell Neoplasms of Gastrointestinal Tract, Including Gastrointestinal Stromal Tumors
Exfoliative Cytopathology: Cerebrospinal Fluid
	Normal Cerebrospinal Fluid and Contamination by Normal Elements
	Infectious Meningitis
	Aseptic and Mollaret Meningitis
	Subarachnoid Hemorrhage
	Neurodegenerative Diseases
	Primary Brain Tumors
	Leukemia and Lymphoma
	Metastasis in CSF
Exfoliative Cytopathology: Pleural, Peritoneal, Pericardial, and Pelvic Fluid and Washings
	Normal Cellular Components and Reactive Mesothelial Proliferations
	Infectious Conditions
	Autoimmune Diseases
	Malignant Effusion, Mesothelioma
	Lymphoid Effusions and Lymphomas
	Primary Effusion Lymphoma
	Endometriosis and Endosalpingiosis
	Ovarian Neoplasms
	Immunocytochemistry, Histochemistry, and Other Ancillary Techniques
Exfoliative Cytopathology: Urinary Cytology
	Normal Urinary Cytology, Specimen Types, and Reporting Terminology
	Ileal Conduit Specimens
	Noninfectious Benign Conditions
	Infectious Benign Conditions
	Reactive Urothelial Changes
	Low-Grade Urothelial Lesions
	High-Grade Urothelial Dysplasia/Carcinoma/Carcinoma In Situ
	Squamous Cell Carcinoma of Urinary Bladder
	Adenocarcinoma of Urinary Bladder
	Other Malignancies in Urinary Cytology
	Renal Pelvic Cytology
	Ancillary Testing, UroVysion, and Others
Fine-Needle Aspiration, Superficial: Overview
	Superficial Aspiration Technique
Fine-Needle Aspiration, Superficial: Thyroid Gland
	Ultrasound-Guided Thyroid Fine-Needle Aspiration
	Thyroid Fine-Needle Aspiration Reporting Terminology and Specimen Adequacy
	Adenomatous (Benign Follicular) Nodule
	Chronic Lymphocytic/Hashimoto Thyroiditis
	Granulomatous Thyroiditis
	Graves Disease/Diffuse Toxic Goiter
	Pigmented Thyroid Lesions and Crystals
	Atypia of Undetermined Significance/Follicular Lesion of Undertermined Significance
	Follicular Neoplasm/Suspicious for a Follicular Neoplasm
	Follicular Neoplasm, Hürthle Cell (Oncocytic) Type
	Papillary Thyroid Carcinoma, Classic Variant
	Medullary Thyroid Carcinoma
	Poorly Differentiated Thyroid Carcinoma
	Anaplastic Thyroid Carcinoma
	Thyroid Lymphoma
	Metastatic Carcinoma to Thyroid
	Other Nonneoplastic and Neoplastic Thyroid Lesions Encountered on Thyroid FNA
Fine-Needle Aspiration, Superficial: Parathyroid Gland
	Parathyroid Cyst, Adenoma, and Carcinoma
Fine-Needle Aspiration, Superficial: Lymph Nodes
	Indications for Aspiration and Techniques
	FNA Sample Prep and Triage in Evaluating Suspected Lymphoma
	Inflammatory and Reactive Lymphoid Hyperplasia
	Granulomatous Lymphadenitis, Infectious and Sarcoid
	Rosai-Dorfman Disease
	Metastatic Malignancies (Carcinoma, Melanoma)
	HPV-Positive Head and Neck Squamous Cell Carcinoma
	Small Lymphocytic Lymphoma
	Lymphoplasmacytic Lymphoma
	Mantle Cell Lymphoma
	Nodal Marginal Zone Lymphoma
	Follicular Lymphoma
	Burkitt Lymphoma
	Large B-Cell Lymphoma
	Plasmacytoma
	Mediastinal Large B-Cell Lymphoma
	Plasmablastic Lymphoma
	Peripheral T-Cell Lymphoma
	Mycosis Fungoides
	Angioimmunoblastic Lymphoma
	ALK(+) Anaplastic Large Cell Lymphoma
	T-Cell Lymphoblastic Lymphoma
	Nodular Lymphocyte-Predominant Hodgkin Lymphoma
	Classical Hodgkin Lymphoma
Fine-Needle Aspiration, Superficial: Salivary Gland
	Approach to Interpretation of Salivary Gland Aspiration Biopsies and Reporting Terminology (Milan System)
	Normal Salivary Gland and Sialadenitis on Aspiration
	Cysts
	Pleomorphic Adenoma
	Warthin Tumor
	Myoepithelioma
	Oncocytoma, Salivary Gland
	Adenoid Cystic Carcinoma
	Acinic Cell Carcinoma
	Mucoepidermoid Carcinoma
	Basaloid Neoplasms, Benign and Malignant
	Carcinoma Ex Pleomorphic Adenoma
	Adenocarcinoma, Not Otherwise Specified
	Polymorphous Low-Grade Adenocarcinoma
	Salivary Duct Carcinoma
	Secretory Carcinoma
	Myoepithelial Carcinoma
	Cribriform Adenocarcinoma
	Metastatic Carcinoma
	Primary and Metastatic Nonepithelial Tumors
Fine-Needle Aspiration, Superficial: Breast
	Role of Fine-Needle Aspiration of Breast, Techniques and Triple Test
	Inflammatory and Granulomatous Conditions
	Fat Necrosis
	Nonproliferative and Proliferative Changes in Breast
	Radial Scar/Complex Sclerosing Lesion
	Gynecomastia
	Mucocele-Like Lesion
	Fibroadenoma
	Granular Cell Tumor of Breast
	Papillary Neoplasms
	Myofibroblastoma, Mammary
	Ductal Carcinoma and Variants of Invasive Mammary Carcinoma
	Lobular Carcinoma
	Phyllodes Tumor
	Angiosarcoma and Other Sarcomas
	Lymphomas and Metastatic Tumors
	Cytology Specimens for Risk Assessment of Breast Cancer
Fine-Needle Aspiration, Superficial: Skin and Subcutaneous Cytology
	Cutaneous and Adnexal Cytology
Fine-Needle Aspiration, Deep Organs and Tissues: Overview
	Techniques and Modalities of Deep Aspiration Biopsies
Fine-Needle Aspiration, Deep Organs and Tissues: Mediastinum
	Anatomic Compartments and Constituent Tumors
	Mediastinal Cysts and Inflammatory Lesions
	Thymoma
	Thymic Carcinoma
	Germ Cell Tumors
	Neurogenic Tumors
	Metastatic Tumors of Mediastinum
Fine-Needle Aspiration, Deep Organs and Tissues: Liver
	Cytology of Normal Liver
	Inflammatory and Infectious Conditions of Liver
	Hepatocellular Adenoma
	Focal Nodular Hyperplasia
	Hemangioma, Liver
	Hepatocellular Carcinoma
	Hepatoblastoma
	Liver Metastasis
Fine-Needle Aspiration, Deep Organs and Tissues: Kidney
	Cytology of Normal Kidney
	Renal Cysts
	Angiomyolipoma
	Oncocytoma, Kidney
	Metanephric Adenoma
	Metanephric Stromal Tumor
	Xanthogranulomatous Pyelonephritis/Malakoplakia
	Clear Cell Renal Cell Carcinoma
	Papillary Renal Cell Carcinoma
	Clear Cell Papillary Renal Cell Carcinoma
	Chromophobe Renal Cell Carcinoma
	Collecting Duct Carcinoma
	Renal Medullary Carcinoma
	Mucinous Tubular and Spindle Cell Carcinoma of Kidney
	Carcinoid Tumor
	Primary Renal Sarcomas in Adults
	Renal Lymphomas
	Nephroblastoma (Wilms Tumor)
	Clear Cell Sarcoma of Kidney
	Congenital Mesoblastic Nephroma
	Rhabdoid Tumor of Kidney
	Metastatic Tumors to Kidney
	Urothelial Carcinoma
Fine-Needle Aspiration, Deep Organs and Tissues: Adrenal Gland
	Cytology of Normal Adrenal Gland
	Adrenal Cortical Adenoma
	Metastatic Tumors to Adrenal Gland
	Pheochromocytoma
Fine-Needle Aspiration, Deep Organs and Tissues: Pancreas
	Cytology of Normal Pancreas
	Pancreatic Cytology Reporting Terminology, Cyst Evaluation
	Pancreatitis
	Lymphoepithelial Cyst of Pancreas
	Intra- and Peripancreatic Splenules
	Serous Microcystic Adenoma
	Mucinous Cystic Neoplasm
	Intraductal Papillary Mucinous Neoplasm
	Solid Pseudopapillary Neoplasm
	Pancreatic Neuroendocrine Tumor
	Pancreatic Ductal Adenocarcinoma
	Unusual Variants of Ductal Carcinoma
	Acinar Cell Carcinoma
	Lymphoma and Secondary Tumors of Pancreas
Fine-Needle Aspiration, Deep Organs and Tissues: Bone
	Approach to Cytologic/Small Biopsy Diagnosis of Primary Bone Tumors
	Chondromas of Bone and Soft Tissue
	Chondroblastoma
	Giant Cell Tumor
	Osteoblastoma
	Adamantinoma
	Langerhans Cell Histiocytosis
	Chordoma
	Osteosarcoma
	Chondrosarcoma
	Ewing Sarcoma
	Bone Lymphoma
	Metastatic Tumors of the Bone
Fine-Needle Aspiration, Deep Organs and Tissues: Soft Tissue
	Approach to Cytologic/Small Biopsy Diagnosis of Primary Soft Tissue Lesions
	Benign Adipose Tissue Tumors
	Liposarcoma
	Fibrosarcoma
	Myofibroblastoma
	Low-Grade Myofibroblastic Sarcoma
	Giant Cell Tumor of Tendon Sheath
	Undifferentiated Pleomorphic Sarcoma
	Smooth Muscle Tumors
	Skeletal Muscle Tumors
	Hemangioma, Soft Tissue
	Epithelioid Hemangioendothelioma
	Angiosarcoma
	Other Reactive and Neoplastic Soft Tissue Entities
	Mesenchymal Chondrosarcoma
	Solitary Fibrous Tumor
	Intramuscular Myxoma
	Synovial Sarcoma
	Epithelioid Sarcoma
	Alveolar Soft Part Sarcoma
	Clear Cell Sarcoma of Soft Tissue
	Desmoplastic Small Round Cell Tumor
Fine-Needle Aspiration, Deep Organs and Tissues: Ophthalmic and Neuropathology
	Approach to Ophthalmic Cytology
	Ophthalmic Cytopathology, Infectious
	Ophthalmic Cytopathology, Neoplastic
	Neuropathology Squash Preparations, Infectious
	Neuropathology Squash Preparations, Glial Neoplasms
	Neuropathology Squash Preparations, Nonglial Neoplasms
Management and Ancillary Testing: Cytopreparatory and Quality Management
	Cytopreparatory Techniques and Instrumentation in Nongynecologic Cytology
	Quality Improvement and Laboratory Management for Cytopathology
Management and Ancillary Testing: Ancillary Testing
	Immunocytochemistry
	Molecular Techniques
Index
Copyright
Title Page
Dedication
Contents
Chapter 1: ‘I’m thinking’ – Oh, but are you?
Chapter 2: Renegade perception
Chapter 3: The Pushbacker sting
Chapter 4: ‘Covid’: The calculated catastrophe
Chapter 5: There is no ‘virus’
Chapter 6: Sequence of deceit
Chapter 7: War on your mind
Chapter 8: ‘Reframing’ insanity
Chapter 9: We must have it? So what is it?
Chapter 10: Human 2.0
Chapter 11: Who controls the Cult?
Chapter 12: Escaping Wetiko
Postscript
Appendix: Cowan-Kaufman-Morell Statement on Virus Isolation
Bibliography
Index