Diabetes Mellitus: Pathophysiology and Therapy: Bayer AG Centenary Symposium Edinburgh, U.K., May 25–28, 1988

Front Matter....Pages I-XXVI
Front Matter....Pages 1-1
Epidemiology — Its Contribution to Understanding of the Etiology, Pathogenesis, and Prevention of Diabetes Mellitus....Pages 5-26
Genetics of Diabetes Mellitus....Pages 27-38
On the Pathogenesis of Insulin-Dependent Diabetes Mellitus — A Discussion of Three Recently Proposed Models....Pages 39-50
Challenging Views on the Pathogenesis of Type I (Insulin-Dependent) Diabetes Mellitus....Pages 51-62
Islet Amyloid and Type 2 Diabetes....Pages 63-70
Insulin Receptor: Role of Receptor Tyrosine Kinase in Insulin Signalling and Action....Pages 73-81
The Kinetics of Insulin, C-Peptide, and Proinsulin in Normal and Diabetic Man....Pages 82-93
Cell Biology of Insulin Action on Glucose Transport and Its Perturbation in Diabetes Mellitus....Pages 94-106
Mechanisms of Insulin Resistance in Obese and Type II Diabetic Subjects....Pages 107-126
Abnormal Glucagon Secretion in Type 2 (Noninsulin-Dependent) Diabetes Mellitus: Causes and Consequences....Pages 127-133
Physiopathology and Possible Etiology of Hormonal Dysregulations and Insulin Resistance in Obese Rats: a Potential Model for Some Human Obesity....Pages 137-141
Models for Studying Diabetic Complications....Pages 142-151
Insulin Analogues — Potentials for Improving Diabetes Treatment....Pages 155-163
Metabolic Inhibitors in the Treatment of Diabetes Mellitus....Pages 164-171
Inhibitors Influencing Carbohydrate Absorption....Pages 172-191
Front Matter....Pages 193-193
Why and How to Involve the Diabetic Patient in his Treatment....Pages 197-206
Advanced Non-Enzymatic Tissue Glycosylation: Biochemical Basis of Late Diabetic Complications....Pages 209-217
Is it Possible to Prevent Late Complications of Diabetes Mellitus?....Pages 218-222
Long-Term Efficacy and Safety of Intensified Insulin Treatment Strategies....Pages 225-233
Is Human Insulin Better than Animal Insulin in the Treatment of Insulin-Dependent Diabetes Mellitus?....Pages 234-241
Front Matter....Pages 193-193
Induction of Partial Remission and Enhancement of Beta-Cell Function by Cyclosporin in Type I Diabetes....Pages 321-334
Role of Abnormal Free Fatty Acid Metabolism in the Pathogenesis and Treatment of Noninsulin-Dependent Diabetes Mellitus....Pages 335-349
Natural History of Diabetes Mellitus in Children....Pages 245-251
Particular Aspects of the Management of Diabetes in Children....Pages 252-264
Aims of Diet in Diabetes Management....Pages 299-308
Practicability of Diet in Diabetes Management....Pages 309-317
The State of the Art in Diabetic Pregnancy....Pages 267-274
Relationship Between Maternal Glucose Levels and Congenital Malformations in the Infant of the Diabetic Mother....Pages 275-280
State of the Art in Pancreas Transplantation....Pages 283-287
What Future for Islet Transplantation in Man?....Pages 288-296
Back Matter....Pages 351-354