Diabetes mellitus : a fundamental and clinical text

Content: 1. The Two Phases of Glucose-Stimulated Insulin Secretion: Mechanisms and Controls / Susanne G. Straub and Geoffrey W.G. Sharp --
2. Insulin Gene Regulation / Michael German --
3. Processing of the Insulin Molecule / Christopher J. Rhodes --
4. Electrophysiology of the Pancreatic [beta]-Cell / Khaled Houamed, Jian Fu, Michael William Roe and Louis H. Philipson --
5. Sulfonylurea Receptors, Andenosine Triphosphate-Sensitive Potassium Channels, and Insulin Secretion / Joseph Bryan and Lydia Aguilar-Bryan --
6. Insulinotropic Glucagon-Like Peptides / Joel F. Habener and Daniel M. Kemp --
7. Detrimental Effects of Chronic Hyperglycemia on the Pancreatic [beta]-Cell / Jack L. Leahy --
8. Glucose Toxicity of the [beta]-Cell: Cellular and Molecular Mechanisms / P. Paul Robertson, Jamie Harmon, Yoshito Tanaka, Phuong Oanh Tran and Vincent Poitout --
9. Lipotoxity / Roger H. Unger --
10. Islet Amyloid in Type 2 Diabetes / Rebecca L. Hull and Steven E. Kahn --
11. Physiologic Action of Insulin / Paul J. Flakoll, Michael D. Jensen and Alan D. Cherrington --
12. Integration of Biochemical and Physiologic Effects of Insulin on the Control of Blood Glucose Concentrations / George Dimitriadis and Eric A. Newsholme --
13. Glucose Counterregulatory Hormones: Physiology, Pathophysiology, and Relevance to Clinical Hypoglycemia / Philip E. Cryer --
14. The Role of Insulin Receptor Substrate Proteins in Insulin Signaling and Metabolic Regulation / Liangyou Rui and Morris F. White --
15. The Insulin Signaling Network and Insulin Action / Yehiel Zick --
16. Knockout Mice as a Tool to the Understanding of Diabetes Mellitus / Katrine Almind, Domenico Accili and C. Ronald Kahn --
17. Regulation of Insulin Action by Protein-Tyrosine Phosphatases / Barry J. Goldstein --
18. Small GTPases and Serine/Threonine Protein Kinase Cascades in Insulin Signal Transduction / Joseph Avruch --
19. Protein Kinase C / Robert V. Farese --
20. Regulation of Glycogen Synthesis / Alexander V. Skurat and Peter J. Roach --
21. Insulin Action on Glucose Transport / Michael P. Czech, James L. Erwin and Mark W. Sleeman --
22. Cellular and Molecular Processes Regulating Glucose Transporter 4 Translocation / June Chunqiu Hou, Alan R. Saltiel and Jeffrey E. Pessin --
23. Hormone-Sensitive Lipase, Perilipins, and the Control of Lipolysis in Adipocytes / Constantine Londos --
24. Role for Phosphodiesterase 3B in Regulation of Lipolysis and Insulin Secretion / Eva Degerman, Tova Rahn Landstrom, Lena Stenson Holst, Olga Goransson, Linda Harndahl, Faiyaz Ahmad, Young-Hun Choi, Silvia Masciarelli, Hanguan Liu and Vincent Manganiello --
25. Gene Regulation / Richard M. O'Brien and Daryl K. Granner --
26. Insulin Degradation / Richard A. Roth, Li Ding and Andrew Becker --
27. Insulin and the Ras-Dependent Signaling Pathway / Marc L. Goalstone and Boris Draznin --
28. Germline Manipulation of Glucose Transport and Glucose Homeostasis / Mike Mueckler --
29. Molecular Links between Peroxisome Proliferator-Activated Receptor-[gamma] and Metabolic Disease / Gregg W. Van Citters and Barry M. Forman --
30. Definition and Classification of Diabetes Mellitus and the Criteria for Diagnosis / Maureen I. Harris --
31. The Natural History of Autoimmunity in Type 1A Diabetes Mellitus / Jennifer M. Barker and George S. Eisenbarth --
32. Genetics of Type 1 Diabetes / Martin Hessner, Xujing Wang and Soumitra Ghosh --
33. Autoantibodies and the Disease Process of Type 1 Diabetes Mellitus / Lisa K. Gilliam, Jerry P. Palmer and Ake Lernmark --
34. Roles of Cell-Mediated Immunity and Cytokines in the Pathogenesis of Type 1 Diabetes Mellitus / Alexander Rabinovitch --
35. Major Histocompatibility Locus and Other Genes That Determine the Risk for Development of Type 1 Diabetes Mellitus / Massimo Pietropaolo and Massimo Trucco --
36. Associations between Immune-Mediated (Type 1) Diabetes and Other Autoimmune Diseases / Svetlana Ten, Anjli Kukreja and Noel Maclaren --
37. Role of Viruses in the Pathogenesis of Type 1 Diabetes Mellitus / Ji-Won Yoon and Hee-Sook Jun --
38. Animal Models of Autoimmune Diabetes Mellitus / John P. Mordes, David V. Serreze, Dale L. Greiner and Aldo A. Rossini --
39. Insights from Transgenic and Gene Targeting Strategies in Type 1 Diabetes / Thomas W.H. Kay and Leonard C. Harrison --
40. Diabetic Ketoacidosis and the Hyperglycemic Hyperosmolar Syndrome / Elizabeth D. Ennis and Robert A. Kreisberg --
41. Application of the Diabetes Control and Complication Trial / Saul Genuth --
42. Diet Therapy in Type 1 Diabetes Mellitus / Christine Beebe --
43. Exercise for the Patient with Type 1 Diabetes Mellitus / Jeanne H. Steppel and Edward S. Horton --
44. Insulin Therapy and Home Monitoring for Type 1 Diabetes Mellitus / Stuart J. Brink --
45. Immune Intervention / Jay S. Skyler and Jennifer B. Marks --
46. Islet Cell Transplantation / Antonello Pileggi, Rodolfo Alejandro, Daniel H. Mintz, Camillo Ricordi and Norma S. Kenyon --
47. Islet Transplantation / Breay W. Paty, Edmond A. Ryan, Jonathan R.T. Lakey and A.M. James Shapiro --
48. Pancreas Transplantation / David E.R. Sutherland, Rainer W.G. Gruessner, S. Michael Mauer and Angelika C. Gruessner --
49. Gene Therapy for Metabolic Disease / Anthony T. Cheung and Timothy J. Kieffer --
50. Surrogate [beta]-cells for Insulin Replacement Therapy / Christopher B. Newgard and Shimon Efrat --
51. Stem Cells / Anandwardhan A. Hardikar and Marvin C. Gershengorn --
52. Epidemiology of Type 2 Diabetes Mellitus / Dana Dabelea and Richard F. Hamman --
53. Metabolic Abnormalities in the Development of Type 2 Diabetes Mellitus / P. Antonio Tataranni and Clifton Bogardus --
54. Noninvasive Imaging of Insulin Action and Resistance in Humans / David E. Kelley and Frederico G.S. Toledo --
55. Genetics of Human Obesity / Oluf Pedersen and Soren M. Echwald --
56. Obesity: Treatment / Xavier Pi-Sunyer --
57. Obesity in Type 2 Diabetes Mellitus / Henning Beck-Nielsen and Ole Hother-Nielsen --
58. Effects of Aging Glucose Homeostasis / Annette M. Chang and Jeffrey B. Halter --
59. Drug-Induced Diabetes Mellitus / Richard J. Comi --
60. Insulin Secretion in Type 2 Diabetes Mellitus / Gordon C. Weir and Susan Bonner-Weir --
61. Insulin Resistance and Its Consequences: Type 2 Diabetes Mellitus and the Insulin Resistance Syndrome / Gerald M. Reaven --
62. Glucose Transporters and Pathophysiologic States / E. Dale Abel, Peter R. Shepherd and Barbara B. Kahn --
63. Glucose Toxicity: Effect of Chronic Hyperglycemia on Insulin Action / Luciano Rossetti --
64. Inflammation, Tumor Necrosis Factor-[alpha], and Insulin Resistance / Gokhan S. Hotamisligil --
65. Adipokines: Regulators of Metabolic Integration and Energy Metabolism / Tsu-Shuen Tsao, Christopher Hug and Harvey F. Lodish --
66. Fatty Acids and Insulin Resistance / Guenther Boden --
67. Triglyceride in Muscle / Daniel T. Stein --
68. Candidate Genes for Type 2 Diabetes Mellitus / Mona M. Sabra, Alan R. Shuldiner and Kristi D. Silver --
69. Genetic Syndromes Associated with Severe Insulin Resistance: Mutations in the Insulin Receptor Gene and Lipotrophic Diabetes / Simeon I. Taylor, Elif Arioglu Oral and Domenico Accili --
70. Maturity-Onset Diabetes of the Young: A Model for Genetic Studies of Diabetes Mellitus / Stefan S. Fajans and Graeme I. Bell --
71. Rodent Genetic Models of Obesity and Type 2 Diabetes Mellitus / Marc L. Reitman --
72. Primate Animal Models of Type 2 Diabetes / Barbara C. Hansen --
73. Preventing Type 2 Diabetes: The Diabetes Prevention Program / David M. Nathan, Richard F. Hamman, Sanford Garfield, Anne Brenneman, Sarah F. Fowler and William C. Knowler --
74. Dietary Therapy in Type 2 Diabetes Mellitus: Spreading the Nutrient Load / David J.A. Jenkins, Alexandra L. Jenkins, Livia S.A. Augustin and Cyril W.C. Kendall. 75. Exercise in Patients with Type 2 Diabetes Mellitus / Jeanne H. Steppel and Edward S. Horton --
76. Insulin Secretogogues: Sulfonylureas, Meglitinides, and Phenylalanine Derivatives / Harold E. Lebovitz --
77. Metformin / Alan J. Garber --
78. Peroxisome Proliferator-Activated Receptor Modulators / Garret J. Etgen, Melvin J. Prince and Jose F. Caro --
79. [alpha]-Glucosidase Inhibitors in the Treatment of Diabetes / Markus Rupp --
80. Glinides / James E. Foley and Lajwanti S. Khemlani --
81. Combination Therapy in Type 2 Diabetes Mellitus / Stanley H. Hsia and Mayer B. Davidson --
82. Intensive Insulin Therapy for Patients with Type 2 Diabetes / Sunder Mudaliar and Steven V. Edelman --
83. Hypoglycemia in Type 2 Diabetes Mellitus / Mark R. Burge, Aruna Chelliah and David S. Schade --
84. New Therapies to Promote Insulin Action / Guoqiang Jiang, Bei B. Zhang and David E. Moller --
85. Intermediary Metabolism during Pregnancy: Implications for Diabetes Mellitus / Thomas A. Buchanan --
86. Effects of Maternal Diabetes Mellitus on Intrauterine Development / Thomas A. Buchanan --
87. Pregnancy and Complications of Diabetes Mellitus: Maternal and Fetal Implications / Barak M. Rosenn and Menachem Miodovnik --
88. Gestational Diabetes Mellitus / Robert E. Ratner and Maureen D. Passaro --
89. Pathophysiology of Diabetic Retinopathy / Emily Y. Chew --
90. Pathogenesis of Diabetic Nephropathy / Gabriella Gruden, Luigi Gnudi and GianCarlo Viberti --
91. Diabetic Neuropathies: An Overview of Clinical Aspects, Pathogenesis, and Treatment / Aaron I. Vinik, Gary L. Pittenger, Patricia Barlow and Anahit Mehrabyan --
92. Diabetes Mellitus, Lipids, and Atherosclerosis / Clay F. Semenkovich --
93. Pathophysiology of Hypertension in Diabetes Mellitus / Naftali Stern, James Sowers and Michael L. Tuck --
94. Macrovascular Complications of Diabetes Mellitus / Helaine E. Resnick, Robert S. Lindsay and Barbara V. Howard --
95. Skin and Diabetes / Efrat Wertheimer --
96. Neonatal Diabetes Mellitus / Mark A. Sperling --
97. Hypoglycemia in the Adult / Monica C. Skarulis and Boaz Hirshberg --
98. Biochemistry and Molecular Cell Biology of Diabetic Complications: A Unifying Mechanism / Susanna Hofmann and Michael Brownlee --
99. Hyperinsulinemia and Insulin Resistance / Ele Ferrannini --
100. The Role of Growth Factors in the Pathogenesis of Diabetic Microvascular Complications / William L. Lowe, Jr. --
101. Oxidative Stress, Inflammation, and Diabetic Complications / Milagros G. Huerta and Jerry L. Nadler --
102. Diabetic Vasculopathy / S.I. McFarlane, P. Kumar, R. Muniyappa, F. El-Atat, A. Aneja and J.R. Sowers.