Cytochrome P450

Content: 
Contributors to volume 206
Pages xi-xvii

Preface
Page xix
Michael R. Waterman, Eric F. Johnson

Volumes in series
Pages xxi-xxxvii

[1] P450 gene nomenclature based on evolution Original Research Article
Pages 3-11
Daniel W. Nebert, David R. Nelson

[2] Modeling of mammalian P450s on basis of P450cam x-ray structure Original Research Article
Pages 11-30
Thomas L. Poulos

[3] Mutagenesis of cytochromes P450cam and b5 Original Research Article
Pages 31-49
Stephen G. Sligar, Djordje Filipovic, Patrick S. Stayton

[4] Chemical modification of interaction between adrenodoxin and cytochrome P450scc Original Research Article
Pages 49-56
Francis S. Millett, Lois M. Geren

[5] Azidowarfarin as photoaffinity probe of cytochromes P450 Original Research Article
Pages 57-63
Laurence S. Kaminsky, Deborah Dunbar, William Lawson

[6] Cell-free analysis of targeting of cytochrome P450 to microsomal membranes Original Research Article
Pages 64-75
Elzbieta Szczesna-Skorupa, Byron Kemper

[7] Biosynthesis and intracellular sorting of mitochondrial forms of cytochrome P450 Original Research Article
Pages 75-81
Tsuneo Omura, Akio Ito

[8] Expression of mammalian cytochrome P450 using vaccinia virus Original Research Article
Pages 85-92
Frank J. Gonzalez, Toshifumi Aoyama, Harry V. Gelboin

[9] Expression of mammalian cytochrome P450 using baculovirus Original Research Article
Pages 93-99
Frank J. Gonzalez, Shioko Kimura, Shinji Tamura, Harry V. Gelboin

[10] Heterologous expression of mammalian P450 in COS cells Original Research Article
Pages 100-108
Barbara J. Clark, Michael R. Waterman

[11] Expression of mammalian P450s in Escherichia coli Original Research Article
Pages 108-116
Todd D. Porter, Jane R. Larson

[12] V79 Chinese hamster cells genetically engineered for stable expression of cytochromes P450 Original Research Article
Pages 117-123
Johannes Doehmer, Franz Oesch

[13] Expression of cytochrome P450 cDNAs in human B lymphoblastoid cells: Applications to toxicology and metabolite analysis Original Research Article
Pages 123-129
Charles L. Crespi

[14] Expression of mammalian cytochrome P450 enzymes using yeast-based vectors Original Research Article
Pages 130-145
F. Peter Guengerich, William R. Brian, Marie-AgnГЁs Sari, John T. Ross

[15] Genetic analysis of cytochrome P450 system Original Research Article
Pages 149-166
Nigel K. Spurr, Alan C. Gough, C.A. Dale Smith, C. Roland Wolf

[16] Functional analysis of mutant P450(C21) genes in COS cell expression system Original Research Article
Pages 166-173
Yujiro Higashi, Yoshiaki Fujii-Kuriyama

[17] Genetic polymorphism of debrisoquine oxidation: restriction fragment analysis and allele-specific amplification of mutant alleles of CYP2D6 Original Research Article
Pages 173-183
Markus H. Heim, Urs A. Meyer

[18] Characterization of human P450IIC isozymes by using yeast expression system Original Research Article
Pages 183-190
Ryuichi Kato, Toshio Yasumori, Yasushi Yamazoe

[19] Production of site-specific P450 antibodies using recombinant fusion proteins as antigens Original Research Article
Pages 193-201
Thomas Friedberg, Wolfgang Kissel, Michael Arand, Franz Oesch

[20] Immunoisolation of human microsomal cytochromes P450 using autoantibodies Original Research Article
Pages 201-209
Ulrich M. Zanger

[21] Identification of human cytochrome P450s as autoantigens Original Research Article
Pages 210-220
Michael P. Manns, Eric F. Johnson

[22] Antipeptide antibodies in studies of cytochromes P450IA Original Research Article
Pages 220-233
Robert J. Edwards, Bernard P. Murray, Alan R. Boobis

[23] Production and purification of antibodies against rat liver P450 enzymes Original Research Article
Pages 233-245
Andrew Parkinson, Brian Gemzik

[24] Rat hepatic P450IIA and P450IIC subfamily expression using catalytic, immunochemical, and molecular probes Original Research Article
Pages 249-267
David J. Waxman

[25] Expression of genes within mouse IIA and IID subfamilies: Simultaneous measurement of homologous P450 mRNAs Original Research Article
Pages 267-273
Masahiko Negishi, Barbara Burkhart, Kaoru Aida

[26] CYP4A subfamily: Functional analysis by immunohistochemistry and in Situ hybridization Original Research Article
Pages 273-283
James P. Hardwick

[27] Quantitation of related gene products by nuclear run-on and northern blot analysis Original Research Article
Pages 284-290
Robert H. Tukey, Steven T. Okino

[28] Isolating cytochrome P450 cDNA and genomic clones: Library screening with synthetic DNA oligomers Original Research Article
Pages 291-301
Christopher Hassett, Richard Ramsden, Curtis J. Omiecinski

[29] P450 Phosphorylation in isolated hepatocytes and in Vivo Original Research Article
Pages 305-315
John A. Koch, David J. Waxman

[30] Cytochrome P450 turnover Original Research Article
Pages 315-325
Maria Almira Correia

[31] Induction of diabetes and evaluation of diabetic state on P450 expression Original Research Article
Pages 325-331
John B. Schenkman

[32] Hepatocyte culture in study of P450 regulation Original Research Article
Pages 335-344
Donna Li, Erin G. Schuetz, Philip S. Guzelian

[33] Induction protocols for cytochromes P450IIIA in Vivo and in primary cultures of animal and human hepatocytes Original Research Article
Pages 345-353
Martine Daujat, Lydiane Pichard, Isabelle Fabre, Thierry Pineau, GГ©rard Fabre, Claude Bonfils, Patrick Maurel

[34] Induction protocols for the cytochrome P450IVA subfamily in animals and primary hepatocyte cultures Original Research Article
Pages 353-364
G. Gordon Gibson, Brian G. Lake

[35] Cytochrome P450 expression and metabolism in isolated rabbit renal epithelium Original Research Article
Pages 364-371
Dennis R. Koop, Ronald M. Laethem, Arthur L. Goldner, Janice G. Douglas

[36] Culturing steroidogenic cells Original Research Article
Pages 371-380
Peter J. Hornsby, Jan M. McAllister

[37] Selections for and against cells possessing cytochrome P450IA1-dependent aryl hydrocarbon hydroxylase activity Original Research Article
Pages 381-400
Oliver Hankinson

[38] Use of gel retardation to analyze protein-DNA interactions upstream of CYPIA1 gene Original Research Article
Pages 403-408
Emily S. Shen, Cornelis J. Elferink, James P. Whitlock Jr.

[39] Xenobiotic responsive elements controlling inducible expression by planar aromatic compounds and phenolic antioxidants Original Research Article
Pages 409-420
Thomas H. Rushmore, Cecil B. Pickett

[40] Induction of cytochromes P450IA1 and P450IA2 and measurement of catalytic activities Original Research Article
Pages 423-431
A.D. Rodrigues, R.A. Prough

[41] П‰- and (П‰-1)-hydroxylation of eicosanoids and fatty acids by high-performance liquid chromatography Original Research Article
Pages 432-441
Richard T. Okita, Joan E. Clark, Janice Rice Okita, Bettie Sue Siler Masters

[42] Cytochrome P450 arachidonic acid epoxygenase: Stereochemical characterization of epoxyeicosatrienoic acids Original Research Article
Pages 441-453
Jorge H. Capdevila, Elizabeth Dishman, Armando Karara, J.R. Falck

[43] Measurement of steroid hydroxylation reactions by high-performance liquid chromatography as indicator of P450 identity and function Original Research Article
Pages 454-462
Michael P. Arlotto, John M. Trant, Ronald W. Estabrook

[44] P450-catalyzed steroid hydroxylation: Assay and product identification by thin-layer chromatography Original Research Article
Pages 462-476
David J. Waxman

[45] Assay of aromatase activity Original Research Article
Pages 477-483
Edwin D. Lephart, Evan R. Simpson

[46] Reversed-phase high-performance liquid chromatography assay of cholesterol 7О±-hydroxylase Original Research Article
Pages 483-491
John Y.L. Chiang

[47] Induction, inhibition, and analysis of vitamin D metabolism in cultured cells Original Research Article
Pages 491-501
Joseph L. Napoli, Cathleen A. Martin, Ronald L. Horst

[48] Measurement of cytochrome P450 activation of xenobiotics using the ames Salmonella test Original Research Article
Pages 501-509
M.E. McManus, R.A. McKinnon

[49] Bufuralol, dextromethorphan, and debrisoquine as prototype substrates for human P450IID6 Original Research Article
Pages 509-517
Thomas Kronbach

[50] Breath tests as noninvasive assays of P450s Original Research Article
Pages 517-522
Paul B. Watkins

[51] Site of action of substrates requiring cytochrome b5 for oxidation by cytochrome P450 Original Research Article
Pages 523-529
Lucy A. Waskell, J.L. Vigne, G. Vergeres

[52] Mechanism-based inactivation of cytochrome P450: Isolation and characterization of N-alkyl heme adducts Original Research Article
Pages 533-540
Paul R. Ortiz de Montellano

[53] Dihalomethyl compounds as mechanism-based inactivators of cytochromes P450 Original Research Article
Pages 540-548
James R. Halpert, Jeffrey C. Stevens

[54] Active site-directed inhibitors of steroid hydroxylase cytochromes P450 Original Research Article
Pages 548-558
Larry E. Vickery

[55] Cytochrome P450 metabolic intermediate complexes from macrolide antibiotics and related compounds Original Research Article
Pages 559-573
Michael R. Franklin

[56] Isolation of P450 enzymes from human liver Original Research Article
Pages 577-587
Judy L. Raucy, Jerome M. Lasker

[57] Constitutive and inducible forms of cytochrome P450 from hepatic mitochondria Original Research Article
Pages 587-594
Rass M. Shayiq, Sankar Addya, Narayan G. Avadhani

[58] Induction, purification, and characterization of cytochrome P450IIE Original Research Article
Pages 595-603
Chung S. Yang, Christopher J. Patten, Hiroyuki Ishizaki, Jeong-Sook H. Yoo

[59] Purification and characterization of cytochromes P450 in rabbit nasal microsomes Original Research Article
Pages 603-612
Xinxin Ding, Minor J. Coon

[60] Bacterial cytochromes P450: Isolation and identification Original Research Article
Pages 612-620
Julian A. Peterson, J.-Y. Lu

[61] Characterization of cytochrome P450 in extrahepatic tissues Original Research Article
Pages 623-631
Richard M. Philpot

[62] Identification and localization of cytochromes P450 expressed in brain Original Research Article
Pages 631-640
Margaret Warner, Ragnhild Ahlgren, Peter G. Zaphiropoulos, Shin-Ichi Hayashi, Jan-Г…ke Gustafsson

[63] Identification of cytochrome P450 in extrahepatic tissues by cross-hybridization of oligonucleotides and cDNAs Original Research Article
Pages 640-648
Maria Strömstedt, Peter G. Zaphiropoulos, Jan-Åke Gustafsson

[64] Identification and localization of cytochromes P450 in gut Original Research Article
Pages 648-655
Henry W. Strobel, Dianne K. Hammond, Terry B. White, James W. White

Author index
Pages 657-684

Subject index
Pages 685-716