Corneal Regeneration: Therapy and Surgery

Front Matter ....Pages i-xxv
Front Matter ....Pages 1-1
 Corneal Anatomy  (Miguel Gonzalez-Andrades, Pablo Argüeso, Ilene Gipson)....Pages 3-12
 Corneal Healing  (Veronica Vargas, Francisco Arnalich-Montiel, Jorge L. Alió del Barrio)....Pages 13-22
 Corneal Tissue Engineering  (Mohammad Mirazul Islam, Roholah Sharifi, Miguel Gonzalez-Andrades)....Pages 23-37
Front Matter ....Pages 39-39
 Stem Cells: Concept, Properties, and Characterization  (Natalia Escacena-Acosta, Javier Lopez-Beas, Christian Claude Lachaud, Mehrdad Vakilian, Juan Rigoberto Tejedo, Vivian Capilla-González et al.)....Pages 41-55
 Corneal Stem Cells: Identification and Methods of Ex Vivo Expansion  (Christian Claude Lachaud, Abdelkrim Hmadcha, Bernat Soria)....Pages 57-75
 Corneal Epithelial Stem Cells: Methods for Ex Vivo Expansion  (Gustavo S. Figueiredo, Hardeep Singh Mudhar, Majlinda Lako, Francisco C. Figueiredo)....Pages 77-97
 Corneal Stromal Stem Cell: Methods for Ex Vivo Expansion  (Olena Al-Shymali, Jorge L. Alió del Barrio, James L. Funderburgh)....Pages 99-108
 Corneal Endothelial Cells: Methods for Ex Vivo Expansion  (Stephen Wahlig, Matthew Lovatt, Gary Swee-Lim Peh, Jodhbir S. Mehta)....Pages 109-122
 Corneal Regeneration: Use of Extracorneal Stem Cells  (Christian Claude Lachaud, Abdelkrim Hmadcha, Bernat Soria)....Pages 123-144
 One Cell, Two Phenotypes: Capturing Pluripotency for Corneal Regeneration  (Trevor Sherwin, Carol Ann Greene, Colin R. Green, Kushant R. Kapadia)....Pages 145-154
 Corneal Stem Cell-Based Therapies  (Yuzuru Sasamoto, Yoshinori Oie, Kohji Nishida)....Pages 155-172
Front Matter ....Pages 173-173
 Ocular Surface Epithelium: Applied Anatomy  (Harminder Singh Dua, Dalia G. Said)....Pages 175-190
 Classical Techniques for Limbal Transplantation  (Rafael I. Barraquer, Juan Alvarez de Toledo)....Pages 191-211
 Simple Limbal Epithelial Transplantation: An Update  (Nandini Venkateswaran, Guillermo Amescua)....Pages 213-219
 Cell Therapy Using Ex Vivo Cultured Limbal Cells: CLET and Equivalent  (Paolo Rama, Giulio Ferrari)....Pages 221-224
 Cell Therapy Using Cultivated Oral Mucosal Epithelial Transplant (COMET)  (Roberto Fernández Buenaga, Sajjad Ahmad)....Pages 225-230
 Cell Therapy Using Extraocular Mesenchymal Stem Cells  (Teresa Nieto-Miguel, Sara Galindo, Marina López-Paniagua, Inmaculada Pérez, José M. Herreras, Margarita Calonge)....Pages 231-262
 Cell-based Therapy Using Induced Plutipotent Stem Cell  (Ricardo Pedro Casaroli-Marano)....Pages 263-276
 Cultivated Limbal Stem Cell Transplantation: Indications and Technique  (Joséphine Behaegel, Sorcha Ní Dhubhghaill, Marie-José Tassignon)....Pages 277-290
 Optimizing the Ocular Surface for Regenerative Surgery: What Is Important and What Is Essential for the Outcome  (Kai B. Kang, Ali R. D’jalilian)....Pages 291-297
 Stem Cell Spheres for Corneal Regeneration  (Salim Ismail, Jennifer J. McGhee, Ye Li, Jeremy John Mathan, Jinny Jung Yoon, Himanshu Wadhwa et al.)....Pages 299-316
 Eye Platelet-Rich Plasma (E-PRP) for Corneal Regeneration  (Alejandra E. Rodríguez, Jorge L. Alió)....Pages 317-345
Front Matter ....Pages 347-347
 Applied Anatomy of the Corneal Stroma  (Harminder Singh Dua, Dalia G. Said)....Pages 349-362
 Confocal Microscopy of the Cornea in a Clinical Model of Corneal Stromal Expansion Using Adipose Stem Cells and Corneal Decellularized Laminas in Patients with Keratoconus  (Mona El Zarif, Karim Abdul Jawad, Jorge L. Alió)....Pages 363-386
 Limbal Stromal Stem Cells in Corneal Wound Healing: Current Perspectives and Future Applications  (Noopur Mitragotri, Mukesh Damala, Vivek Singh, Sayan Basu)....Pages 387-402
 Cell Therapy of the Corneal Stroma Using Ex Vivo Cultured Extraocular Cells  (Jorge L. Alió del Barrio)....Pages 403-415
Front Matter ....Pages 417-417
 Corneal Endothelium: Applied Anatomy  (Francisco Arnalich-Montiel)....Pages 419-424
 Corneal Endothelium: Isolation and Cultivation Methods  (David Mingo-Botín, Marie Joan Therese D. Balgos, Francisco Arnalich-Montiel)....Pages 425-436
 Corneal Endothelial Cell Transplantation: Animal Models  (Brad P. Barnett, Albert S. Jun)....Pages 437-454
 Cell Based Therapy for Corneal Endothelial Regeneration  (Noriko Koizumi, Naoki Okumura)....Pages 455-462
 Corneal Endothelium Regeneration: Future Prospects  (Wei-Ting Ho, Hsin-Yu Liu, Fung-Rong Hu, I-Jong Wang)....Pages 463-473
Front Matter ....Pages 475-475
 Umbilical Cord Stem Cells in the Treatment of Corneal Diseases  (Mohammed Ziaei, Jie Zhang, Dipika V. Patel, Charles N. J. McGhee)....Pages 477-483
 Dysfunctional Corneal Endothelium: Delivery of Cell Therapy  (Stephen Wahlig, Gary Swee-Lim Peh, Matthew Lovatt, Jodhbir S. Mehta)....Pages 485-497
Back Matter ....Pages 499-507