Computer applications in biotechnology : a postprint volume from the 6th International Conference, Garmisch-Partenkirchen, Germany, 14-17 May 1995

Content: 
Front Matter, Page i
Copyright, Page ii
6th INTERNATIONAL CONFERENCE ON COMPUTER APPLICATIONS IN BIOTECHNOLOGY - CAB 6, Page iii
STATISTICAL DATA-PROCESSING FROM ON-LINE LASER TUBIDIMETER AND AUTO-FEEDING OF NATURAL COMPLEX NUTRIENTS IN SEMI-BATCH CULTURES, Pages 1-5, Tsuneo Yamane, Yasuyuki Kadotani, Wataru Hibino, Kohji Miyamoto, Minoru Kominami
MODEL-AIDED ON-LINE GLUCOSE MONITORING FOR COMPUTER-CONTROLLED HIGH CELL DENSITY FERMENTATIONS, Pages 6-11, M. Pfaff, E. Wagner, R. Wenderoth, U. Knüpfer, R. Guthke, D. Riesenberg
DEPROTECTION MONITORING IN SPPS: CONDUCTIMETRIC VERSUS SPECTROPHOTOMETRIC TECHNIQUES, Pages 12-16, Silvio Bicciato, Andrea Bagno, Monica Dettin, Carlo Di Bello
PROJECTIVE REFERENCE EVALUATION - THE RELIABLE EVALUATION TECHNIQUE FOR FLOW INJECTION ANALYSIS SIGNALS, Pages 17-23, B. Hitzmann, K. Schöngarth, A. Löhn, B. Weigel
FEEDBACK CONTROL OF A RECOMBINANT FED-BATCH FERMENTATION USING ON-LINE HPLC MEASUREMENTS, Pages 24-28, V.M. SAUCEDO, S.C. VALENTINOTT, M.N. KARIM, H.W. COLLINS
REAL-TIME RECURSIVE PARAMETER ESTIMATION FOR FAULT DETECTION IN FLOW-INJECTION ANALYSIS SYSTEMS, Pages 29-34, Xiaoan Wu, Karl-Heinz Bellgardt
EXPLORATORY DIAGNOSIS OF LARGE-SCALE CHROMATOGRAPHIC PROCESSES BY PRINCIPAL COMPONENT ANALYSIS, Pages 35-40, R M Chandwani, N Thornhill, B Horstmann, P Kårsnãs, N J Titchener Hooker
PATTERN RECOGNITION FOR PHASE DETECTION IN BIOPROCESSES, Pages 41-46, K. Gollmer, C. Posten
HYBRID SIMULATION OF MICROBIAL BEHAVIOR COMBINING A STATISTICAL PROCEDURE AND FUZZY IDENTIFICATION OF CULTURE PHASES, Pages 47-52, Jun-ichi Horinchi, Michimasa Kishimoto
Seed Data Analysis for Production Fermenter Performance Estimation, Pages 53-58, M. Ignova, J. Glassey, A.C. Ward, G.A. Montague, T.S. Irvine
ARTIFICIAL NEURAL NETWORKS OF IMPROVED RELIABILITY FOR INDUSTRIAL PROCESS SUPERVISION, Pages 59-65, R. Simutis, I. Havlik, F. Schneider, M. Dors, A. Lübbert
REACTION MECHANISMS AND CELL DENSITY ESTIMATORS FOR ANIMAL CELL CULTURES, Pages 66-71, V. Chotteau, G. Bastin, I.M.Y. Mareels, L. Fabry
ADVANCED SUPERVISION OF MAMMALIAN CELL CULTURES USING HYBRID PROCESS MODELS, Pages 72-77, M. Dors, R. Simutis, A. Lübbert
CONTROL OF CONTINUOUS FERMENTATION PROCESSES BY SLIDING MODE DESIGN, Pages 78-82, L. Cazzador, L. Mariani, M. Ignatova
DESIGN OF A CONTROL STRATEGY FOR A LIPASE PRODUCTION PROCESS, Pages 83-88, S. Charbonnier, A. Cheruy
DEVELOPMENT OF INTELLIGENT CONTROL SYSTEMS FOR BIOREACTORS, Pages 89-94, Kazuyuki Shimizu, Kaiming Ye
NEURAL MODELS IN PREDICTIVE CONTROL, Pages 95-100, H.J.L. van Can, H.A.B. te Braake, C. Hellinga, K.Ch.A.M. Luyben, J.J. Heijnen
MODELLING AND CONTROL OF A FED-BATCH FERMENTATION PROCESS USING NEURAL NETWORKS AND ITERATIVE LEARNING METHOD, Pages 101-106, B.S. Zhang, R. Tang, J.R. Leigh
DYNAMICS AND CONTROL OF THE FED-BATCH PRODUCTION OF POLY-β-HYDROXYBUTYRATE BY Methylobacterium extorquens, Pages 107-112, Y. POMERLEAU, M. PERRIER, D. BOURQUE
AN ADVANCED CONTROL METHOD BASED ON THE PATTERN RECOGNIZE AND NEURAL NETWORK FOR BIOPROCESS, Pages 113-117, Shuqing Wang, Wei Zou, Haibin Qu, Yibing Yang
ON-LINE PHYSIOLOGICAL STATE RECOGNITION AND PARAMETER ESTIMATION IN THE METABOLIC REACTION MODEL USING ERROR VECTORS, Pages 118-123, Hiroshi Shimizu, Keigo Miura, Noboru Takiguchi, Suteaki Shioya, Ken-ichi SUGA
MODELLING OF SHORT TERM CRABTREE-EFFECT IN BAKER'S YEAST, Pages 124-129, Manfred Rizzi, Michael Baltes, Werner Mailinger, Uwe Theobald, Matthias Reuss
IN VIVO STATIONARY FLUX DETERMINATION USING 13C NMR ISOTOPE LABELLING EXPERIMENTS, Pages 130-135, W. Wiechert, A.A. de Graaf, A. Marx
A KINETIC MODEL FOR THE PENICILLIN BIOSYNTHETIC PATHWAY IN PENICILLIUM CHRYSOGENUM, Pages 136-141, Jens Nielsen, Henrik S. Jørgensen
COMPARING DIFFERENT MODELLING TECHNIQUES FOR THE ESCHERICHIA COLI FERMENTATION PROCESS, Pages 142-147, Mark R. Warnes, Jarmila Glassey, Gary A. Montague, Bo Kara
DYNAMICAL MODELLING OF A BIOLOGICAL DETOXICATION PROCESS IN A FIXED BED REACTOR, Pages 148-153, Young Bo Hwang, D. Dochain
MATHEMATICAL MODELS FOR GROWTH AND PRODUCTION OF SINGLE PELLETS AND PELLET POPULATIONS, Pages 154-158, R. KING, CH. BÜDENBENDER, G. OSWALD
MODELLING OF STIRRED TANK BIOREACTORS, Pages 159-164, Sven Schmalzriedt, Marc Jenne, Matthias Reuss
BIOFUEL CELL UTILIZING Saccharomyces cerevisiae – MODELLING of the PROCESS, Pages 165-170, Aarne Halme, Xia-Chang Zhang
SIMULATION AND PROFIT ESTIMATION FOR BAKER'S YEAST CONTINUOUS PRODUCTION, Pages 171-176, J.Q. Yuan, S.R. Guo, K.-H. Bellgardt
IMPROVEMENTS IN THE ON-LINE PARAMETER IDENTIFICATION OF BIOPROCESSES, Pages 177-182, R. Schneider, A. Munack
NEURAL NETWORKS IN ESTIMATION AND CONTROL OF ANTIBODY PRODUCTION USING HYBRIDOMA CELLS IN FED-BATCH CULTURES, Pages 183-188, G.S. Oh, B. Eikens, T. Yoshida, M.N. Karim
TEXTURE CHARACTERIZATION OF COLONIES ON SOLID SUBSTRATE, Pages 189-194, M.N. Pons, H. Mona, J.F. Drouin, H. Vivier
PATTERN RECOGNITION METHODS FOR FERMENTATION DATABASE MINING, Pages 195-198, Gregory Stephanopoulos, Georg Locher, Michael Duff
A SYSTEMATIC APPROACH TO STRUCTURED BIOLOGICAL MODELS, Pages 199-204, G. Breuel, E.D. Gilles, A. Kremling
SUBSTRATE CONSUMPTION RATE - NEW CONCEPT OF MEASURING AND MONITORING IN THE ACTIVATED SLUDGE PROCESS, Pages 205-208, Jacek Czeczot
BIOMASS ESTIMATION USING NEURAL NETWORKS AND THE EXTENDED KALMAN FILTER, Pages 209-212, G. Acuña, E. Latrille, G. Corrieu
FLOW CYTOMETRIC MONITORING OF BACTERIAL CELL STATES UNDER GROWTH LIMITING CONDITIONS, Pages 213-216, Thomas Bley, Susann Müller, Andreas Lösche, Jörg-Uwe Ackermann, Wolfgang Babel
STUDY OF SACCHAROMYCES CEREVISIAE YEAST CELLS BY FIELD FLOW FRACTIONATION AND IMAGE ANALYSIS, Pages 217-220, A. Litzén, G.M. Kresbach, M.N. Pons, M. Ehrat, H. Vivier
NEW HARDWARE AND SOFTWARE CONCEPTS FOR FULLY AUTOMATED ANALYSIS AND DATA PROCESSING, Pages 221-225, Alfons Riek, Werner Mailinger, Martina Schütz, Manfred Rizzi, Matthias Reuss
DEVELOPMENT OF ENZYMATIC AUTOANALYZERS FOR MONITORING BIOTECHNOLOGICAL PROCESSES, Pages 226-229, S.B. Itsygin, A.N. Khalutkin, E.R. Ralys, D.D. Greenshpan, V.V. Biryukov
INTERACTIVE EVALUATION OF NMR SPECTRA FROM IN VIVO ISOTOPE LABELLING EXPERIMENTS, Pages 230-233, R. Wittig, M. Möllney, W. Wiechert, A.A. de Graaf
THE ON-LINE COMPARISON OF A MEASURED VS CALCULATED OXYGEN MASS TRANSFER COEFFICIENT - A USEFUL PARAMETER FOR FAULT DIAGNOSIS, Pages 234-238, D R Walwyn
AN EVOLUTIONARY ALGORITHM FOR INITIAL STATE AND PARAMETER ESTIMATION IN COMPLEX BIOCHEMICAL MODELS, Pages 239-242, Karsten Schmidt, Steven H. Isaacs
Maximum Virginiamycin Production Strategy and its Realization in batch Cultivation of Streptomyces virginiae by Autoregulator Addition, Pages 243-246, Suteaki SHIOYA, Young Kook YANG, Hiroshi SHIMIZU, Ken-ich SUGA, Takuya NIHIRA, Yasuhiro YAMADA
IDENTIFIABILITY OF BIOKINETIC MODELS IN AN ACTIVATED SLUDGE PROCESS, Pages 247-250, P. Vanrolleghem, M. Van Daele, D. Dochain
SIMULATION OF PROFIT OPTIMIZATION FOR INDUSTRIAL BAKER'S YEAST CONTINUOUS FERMENTATION, Pages 251-254, S.R. Guo, J.Q. Yuan, K.-H. Bellgardt
PERFORMANCE OF INHIBITION FUNCTIONS WITH TOTAL INHIBITION CONCENTRATION, Pages 255-258, Y.B. Hwang, D. Dochain, G. Bastin
MODEL-BASED ESTIMATION OF REACTION RATES IN STIRRED TANK BIOREACTORS, Pages 259-264, R. Oliveira, E.C. Ferreira, S. Feyo de Azevedo
EDUCATION OF BEER BREWING PHYSIOLOGY AND TECHNOLOGY USING PSI SIMULATION LANGUAGE, Pages 265-268, Jaroslav Votruba, Miloš Kmínek, Marta Palatová
SIMULATION SUPPORT FOR OPERATOR CONTROL OF THE WASTEWATER TREATMENT PLANT, Pages 269-272, Mieczyslaw Metzger
SLIDING ADAPTIVE CONTROL OF BIOTECHNOLOGICAL PROCESSES, Pages 273-276, Laurent Karsenti, Georges Bastin
BIOREACTOR MODELING AND CONTROL BY PRINCIPAL COMPONENT BASED NEURAL NETWORKS, Pages 277-280, Ž. Kurtanjek
DEVELOPMENT OF A MYSTAT WITH ONLINE-SIMULATION METHODS, Pages 281-286, R. Luttmann, G. Bitzer, D. Müller, U. Scheffler, U. Friedriszik
STOCK AND CONCENTRATION DYNAMICS OF ACTIVATED SLUDGE PROCESSES, Pages 287-291, R. Tenno, P. Uronen
STRATEGIES FOR OPTIMAL DISSOLVED OXYGEN (DO) CONTROL, Pages 292-295, R. Mikler, W. Kramer, O. Doblhoff - Dier, K. Bayer
COMPUTER AIDED DESIGN OF LINEARIZING CONTROL FOR BIOPROCESSES, Pages 296-300, Bernard REMOND, Arlette CHERUY
BioX++ – NEW RESULTS AND CONCEPTIONS CONCERNING THE INTELLIGENT CONTROL OF BIOTECHNOLOGICAL PROCESSES, Pages 301-304, K.D. BETTENHAUSEN, S. GEHLEN, P. MARENBACH, H. TOLLE
FUZZY CONTROL OF THE SUBSTRATE CONCENTRATION IN A BIOREACTOR, Pages 305-308, M. Boll, F. Dörrscheidt, D.C. Hempel
EXPERT SYSTEM WITH FRAME DATA FOR INFERENCE OF SUITABLE CULTURE CONDITION, Pages 309-312, Michimasa Kishimoto, Hideyuki Suzuki
NEURAL NETWORKS IN LYSINE FERMENTATION, Pages 313-316, S. Linko, Y.-H. Zhu, P. Linko
IDENTIFICATION AND CONTROL DURING FERMENTATION START-UP - A METHOD TO AVOID SYNCHRONOUS GROWTH IN CONTINOUOUS CULTURES, Pages 317-320, Hanne Møller, Sten Bay Jørgensen
MODELING AND CONTROL OF A CONTINUOUS BIOREACTOR WITH CROSS-FLOW FILTRATION, Pages 321-325, Ying Zhao, Sigurd Skogestad
SIMULATION OF CELL CYCLE DEPENDENT GROWTH AND METABOLISM IN ANIMAL CELL FERMENTATION, Pages 326-329, B. Szperalski, F. Geipel, U. Behrendt, J. Wahl
AN ARTIFICIAL INTELLIGENCE FRAMEWORK OF GENERIC CELL MODELLING, Pages 330-333, PENGCHENG FU, JOHN P. BARFORD
STRUCTURED DYNAMIC MODELLING OF VIRAL INFECTION IN CELL CULTURE, Pages 334-337, CS Sanderson, SH Ong, L Johnson, JP Barford, GW Barton
A TRANSFER-FUNCTION REPRESENTATION FOR FLUX RESPONSES OF A CONTROLLED METABOLIC PATHWAY TO INFLUX AND EFFLUX RATES, Pages 338-341, Naoto Sakamoto
PROTEOLYTIC ACTIVITY OF HYBRIDOMA CULTURES-A SIMULATION STUDY, Pages 342-346, I.M. Møller, P. Frederiksen, C. Emborg
OPTIMISATION OF BIOTECHNICAL PROCESSES UTILISING INTEGRATED METHODS FOR EXPERIMENTAL AND SAMPLING DESIGN, Pages 347-350, Andrea Holmberg, Heikki Haario, Marjut Pokkinen, Raimo Oinas
APPLICATION OF SYMBOLIC COMPUTATION METHODS FOR STABILITY ANALYSIS OF MICROBIAL MIXED POPULATIONS, Pages 351-355, Klaus Mauch, Manfred Rizzi, Naruemol Noisommit-Rizzi, Matthias Reuss
BEST-KIT; Development of Biochemical Engineering System Analyzing TooI-KIT (Kyushu Institute of Technology), Pages 356-359, Masahiro Okamoto, Yoshimitsu Morita
OBJECT ORIENTED DESIGN OF AN ON LINE DATA MANAGER FOR HYBRID BIOPROCESS CONTROL, Pages 360-363, C. Hausmann, W. Wiechert, J. Ebert
AUTHOR INDEX, Pages 364-365
KEYWORD INDEX, Pages 366-367