Computational Systems Biology. From Molecular Mechanisms to Disease

Content: 
Computational Systems Biology, Page i
Computational Systems Biology, Page iii
Copyright, Page iv
Contributors, Pages ix-xi
Preface, Page xiii
Chapter 1 - Introducing Computational Systems Biology, Pages 1-8, Roland Eils, Andres Kriete
Chapter 2 - Structural Systems Biology: Modeling Interactions and Networks for Systems Studies, Pages 9-19, Robert B. Russell,, Gordana Apic, Olga Kalinina, Leonardo Trabuco, Matthew J. Betts, Qianhao Lu
Chapter 3 - Understanding Principles of the Dynamic Biochemical Networks of Life Through Systems Biology, Pages 21-44, Hans V. Westerhoff, Fei He, Ettore Murabito, Frédéric Crémazy, Matteo Barberis
Chapter 4 - Biological Foundations of Signal Transduction, Systems Biology and Aberrations in Disease, Pages 45-64, Ursula Klingmüller, Marcel Schilling, Sofia Depner, Lorenza A. D’Alessandro
Chapter 5 - Complexities in Quantitative Systems Analysis of Signaling Networks, Pages 65-88, Christina Kiel, Luis Serrano
Chapter 6 - Gene Networks: Estimation, Modeling, and Simulation, Pages 89-112, Seiya Imoto, Hiroshi Matsuno, Satoru Miyano
Chapter 7 - Reconstruction of Metabolic Network from Genome Information and its Structural and Functional Analysis, Pages 113-131, Hong-Wu Ma, An-Ping Zeng
Chapter 8 - Standards, Platforms, and Applications, Pages 133-167, Stanley Gu, Herbert Sauro
Chapter 9 - Databases, Standards, and Modeling Platforms for Systems Biology, Pages 169-182, Juergen Eilsa, Elena Herzoga, Baerbel Felder, Christian Lawerenza, Roland Eils
Chapter 10 - Computational Models for Circadian Rhythms: Deterministic versus Stochastic Approaches, Pages 183-222, Jean-Christophe Leloup, Didier Gonze, Albert Goldbeter
Chapter 11 - Top-Down Dynamical Modeling of Molecular Regulatory Networks, Pages 223-239, Reinhard Laubenbacher, Pedro Mendes
Chapter 12 - Discrete Gene Network Models for Understanding Multicellularity and Cell Reprogramming: From Network Structure to Attractor Landscapes Landscape, Pages 241-276, Joseph Xu Zhou, Xiaojie Qiu, Aymeric Fouquier d’Herouel, Sui Huang
Chapter 13 - Stochastic Simulations of Cellular Processes: From Single Cells to Colonies, Pages 277-293, John Cole, Michael J. Hallock, Piyush Labhsetwar, Joseph R. Peterson, John E. Stone, Zaida Luthey-Schulten
Chapter 14 - Advances in Machine Learning for Processing and Comparison of Metagenomic Data, Pages 295-329, Jean-Luc Bouchot, William L. Trimble, Gregory Ditzler, Yemin Lan, Steve Essinger, Gail Rosen
Chapter 15 - Systems Biology of Infectious Diseases and Vaccines, Pages 331-358, Helder I Nakaya
Chapter 16 - Computational Modeling and Simulation of Animal Early Embryogenesis with the MecaGen Platform, Pages 359-405, Julien Delile, René Doursat, Nadine Peyriéras
Chapter 17 - Developing a Systems Biology of Aging, Pages 407-422, Andres Kriete, Mathieu Cloutier
Chapter 18 - Molecular Correlates of Morphometric Subtypes in Glioblastoma Multiforme, Pages 423-454, Hang Chang, Gerald V. Fontenay, Cemal Bilgin, Alexander Borowsky, Paul Spellman, Bahram Parvin
Chapter 19 - Applications in Cancer Research: Mathematical Models of Apoptosis, Pages 455-481, Stefan M. Kallenberger, Stefan Legewie, Roland Eils
Author Index, Pages 483-524
Subject Index, Pages 525-533