Cocaine and Other Stimulants

Front Matter....Pages i-x
Cocaine: 1884–1974....Pages 1-30
Neural Substrates Mediating Amphetamine Responses....Pages 31-45
Mesolimbic and Extrapyramidal Sites for the Mediation of Stereotyped Behaviour Patterns and Hyperactivity by Amphetamine and Apomorphine in the Rat....Pages 47-76
Behavioral Effects of Amphetamine in Brain Damaged Animals: Problems in the Search for Sites of Action....Pages 77-96
Basic Considerations on the Role of Concertedly Working Dopaminergic, Gaba-Ergic, Cholinergic and Serotonergic Mechanisms within the Neo-Striatum and Nucleus Accumbens in Locomotor Activity, Stereotyped Gnawing, Turning and Dyskinetic Activities....Pages 97-141
Release of Neurotransmitters from the Brain in Vivo by Amphetamine, Methylphenidate and Cocaine....Pages 143-160
Distribution and Metabolism of Amphetamine in Tolerant Animals....Pages 161-177
Changes in Brain Catecholamines Induced by Long-Term Methamphetamine Administration in Rhesus Monkeys....Pages 179-185
Neurobiological Antagonism of Cocaine by Lithium....Pages 187-200
On Food Deprivation in Relation to Amphetamine Tolerance....Pages 201-213
Cocaine: Distribution and Metabolism in Animals....Pages 215-228
Behavioral Effects of Cocaine--Metabolic and Neurochemical Approach....Pages 229-240
Small Vessel Cerebral Vascular Changes Following Chronic Amphetamine Intoxication....Pages 241-251
Enhancement of Cocaine-Induced Lethality by Phenobarbital....Pages 253-267
Changes in Neuronal Activity in the Neostriatum and Reticular Formation Following Acute or Long-Term Amphetamine Administration....Pages 269-301
Amygdala Hyperspindling and Seizures Induced by Cocaine....Pages 303-326
Sensitization to Cocaine Following Chronic Administration in the Rat....Pages 327-351
Progressive Changes in Behavior and Seizures Following Chronic Cocaine Administration: Relationship to Kindling and Psychosis....Pages 353-372
Cocaine: Discussion on the Role of Dopamine in the Biochemical Mechanism of Action....Pages 373-407
Chronic Administration of Stimulant Drugs: Response Modification....Pages 409-429
Differential Effects of Serotonin Depletion on Amphetamine-Induced Locomotion and Stereotypy....Pages 431-443
Role of Monoamine Neural Pathways in d-Amphetamine- and Methylphenidate-Induced Locomotor Activity....Pages 445-455
The Effects of Cocaine on the Aggressive Behavior of Mice, Pigeons and Squirrel Monkeys....Pages 457-480
Changes in Individual and Social Behavior Induced by Amphetamine and Related Compounds in Monkeys and Man....Pages 481-522
Reinforcement of Behavior by Cocaine Injections....Pages 523-544
A Comparison of Cocaine and Diethylpropion under Two Different Schedules of Drug Presentation....Pages 545-570
A Preference Procedure that Compares Efficacy of Different Intravenous Drug Reinforcers in the Rhesus Monkey....Pages 571-584
The Effects of Response Contingent and Non-Contingent Shock on Drug Self-Administration in Rhesus Monkeys....Pages 585-598
Drug-Maintained Performance and the Analysis of Stimulant Reinforcing Effects....Pages 599-613
Acute Systemic Effects of Cocaine in Man: A Controlled Study of Intranasal and Intravenous Routes of Administration....Pages 615-628
Cocaine: Blood Concentration and Physiological Effect After Intranasal Application in Man....Pages 629-645
Physiological and Behavioral Effects of Intravenous Cocaine in Man....Pages 647-664
Effects of Intravenous Cocaine on MHPG Excretion in Man....Pages 665-673
Psychologic Test Responses and Methylphenidate....Pages 675-687
The Comparative Psychotogenic Effects of L-Dopa and ET-495....Pages 689-704
Structure-Activity Relationships of Several Amphetamine Drugs in Man....Pages 705-715
Back Matter....Pages 717-721