Clinical Endocrine Oncology, Second Edition

The new edition of Clinical Endocrine Oncology has been fully revised and extended making it the most comprehensive and up-to-date reference available. Written and edited by leading international experts in the field, it sets the standard in multidisciplinary care for patients with endocrine tumors.

The book provides specific and detailed guidance on the basic, clinical, investigative and therapeutic processes required for the thorough evaluation of a patient with a tumor in an endocrine organ. The eighty-four chapters are arranged in seven parts:

• Endocrine Oncology and Therapeutic Options
• Thyroid and Parathyroid Tumors
• Pituitary and Hypothalamic Lesions
• Adrenal and Gonadal Tumors
• Neuroendocrine Tumors and the Clinical Syndromes
• Medical Syndromes and Endocrine Neoplasia
• Endocrine-responsive Tumors and Female Reproductive Hormone Therapy.

This authoritative and practical text will be an invaluable resource for all those working in the field, including endocrinologists, medical oncologists, surgeons, radiation therapists, interventional radiologists, specialist nurses, and clinical scientists.

John A.H. Wass is joined in this edition by a new editor, Ian D. Hay, Professor of Medicine and Endocrinology Research at the Mayo Clinic College of Medicine, Rochester, Minnesota, USA.Content:
Chapter 1 Structure and Development of the Endocrine System (pages 1–17): John F. Morris
Chapter 2 Epidemiology of Endocrine Tumors (pages 18–23): Amanda Nicholson
Chapter 3 Inherited Cancers, Genes, and Chromosomes (pages 24–31): Emma R. Woodward and Eamonn R. Maher
Chapter 4 Hormones, Growth Factors, and Tumor Growth (pages 32–40): Andrew G. Renehan
Chapter 5 Genetic Counseling and Clinical Cancer Genetics (pages 41–48): Lucy Side
Chapter 6 Prospects for Gene Therapy for Endocrine Malignancies (pages 49–57): Christine Spitzweg, Ian D. Hay and John C. Morris
Chapter 7 Tumor Targeting (pages 58–63): Mona Waterhouse and Ashley B. Grossman
Chapter 8 Techniques in Radiation Medicine (pages 64–69): P. Nicholas Plowman
Chapter 9 Interventional Radiology (pages 70–77): Jane Phillips?Hughes and Philip Boardman
Chapter 10 Surgical Management of Endocrine Tumors (pages 78–85): Gustavo G.Fernandez Ranvier and Orlo H. Clark
Chapter 11 Endocrine Tumor Markers (pages 86–101): Stefan K.G. Grebe
Chapter 12 General Management of Cancer Patients (pages 102–107): Marcia Hall
Chapter 13 Assessment of Thyroid Neoplasia (pages 109–115): Kristien Boelaert, Jayne Franklyn and Michael Sheppard
Chapter 14 Thyroid and Parathyroid Imaging (pages 116–123): Conor J. Heaney and Gregory A. Wiseman
Chapter 15 Pathogenesis of Thyroid Cancer (pages 124–129): Jan Zedenius and Theodoros Foukakis
Chapter 16 Papillary Thyroid Carcinoma (pages 130–142): Ian D. Hay
Chapter 17 Follicular Thyroid Carcinoma (pages 143–154): Manisha H. Shah and Matthew D. Ringel
Chapter 18 Anaplastic Thyroid Carcinoma (pages 155–161): Richard T. Kloos
Chapter 19 Thyroid Lymphoma (pages 162–165): Christopher M. Nutting and Kevin J. Harrington
Chapter 20 Radiation?Induced Thyroid Tumors (pages 166–171): David H. Sarne and Arthur Schneider
Chapter 21 Parathyroid Adenomas and Hyperplasia (pages 172–179): Bart L. Clarke
Chapter 22 Parathyroid Carcinoma (pages 180–184): Goran Akerstrom, Per Hellman and Peyman Bjorklund
Chapter 23 Molecular Pathogenesis of Pituitary Adenomas (pages 185–193): Ines Donangelo and Shlomo Melmed
Chapter 24 Functional Assessment of the Pituitary (pages 194–199): John S. Bevan
Chapter 25 Imaging of the Pituitary and Hypothalamus (pages 200–214): James V. Byrne
Chapter 26 Pathology of Tumors of the Pituitary (pages 215–221): Eva Horvath and Kalman Kovacs
Chapter 27 Surgery for Pituitary Tumors (pages 222–230): Simon A. Cudlip
Chapter 28 Pituitary Radiotherapy (pages 231–236): P. Nicholas Plowman
Chapter 29 Prolactinomas (pages 237–245): Mary P. Gillam and Mark E. Molitch
Chapter 30 Acromegaly (pages 246–252): John A.H. Wass
Chapter 31 Cushing's Disease (pages 253–261): John Newell?Price
Chapter 32 Non?Functioning Pituitary Adenomas and Gonadotropinomas (pages 262–267): Maarten O. van Aken, Aart Jan van der Lelij and Steven W.J. Lamberts
Chapter 33 Thyrotropinomas (pages 268–273): Paolo Beck?Peccoz and Luca Persani
Chapter 34 Pituitary Carcinoma (pages 274–277): Olaf Ansorge
Chapter 35 Pituitary Incidentalomas (pages 278–281): Karin Bradley
Chapter 36 Craniopharyngioma (pages 282–287): Niki Karavitaki
Chapter 37 Benign Cysts: Rathke's Cleft Cysts, Mucoceles, Arachnoid Cysts, and Dermoid and Epidermoid Cysts (pages 288–292): Niki Karavitaki
Chapter 38 Hypothalamic Hamartomas and Gangliocytomas (pages 293–297): Lawrence A. Frohman
Chapter 39 Cranial Ependymoma (pages 298–301): Silvia Hofer and Michael Brada
Chapter 40 Perisellar Tumors Including Chordoma, Optic Nerve Glioma, Meningioma, Hemangiopericytoma, and Glomus Tumors (pages 302–309): David Choi and Alan Crockard
Chapter 41 Pineal Tumors: Germinomas and Non?Germinomatous Germ Cell Tumors (pages 310–317): Frank Saran and Sharon Peoples
Chapter 42 Cavernous Sinus Hemangiomas (pages 318–324): Mark E. Linskey
Chapter 43 Langerhans' Cell Histiocytosis (pages 325–330): Matthew F. Gorman, Michelle Hermiston and Katherine K. Matthay
Chapter 44 Pituitary and Hypothalamic Sarcoidosis (pages 331–335): Damian G. Morris and Shern L. Chew
Chapter 45 Imaging of the Adrenal Glands (pages 337–351): Anju Sahdev and Rodney H. Reznek
Chapter 46 Pheochromocytoma (pages 352–359): Andrew Solomon and Pierre Bouloux
Chapter 56 Gestational Trophoblastic Neoplasia (pages 430–434): Tim Crook and Michael J. Seckl
Chapter 47 Peripheral Neuroblastic Tumors (pages 360–369): Bruno De Bernardi, Vito Pistoia, Claudio Gambini and Claudio Granata
Chapter 48 Primary Hyperaldosteronism (pages 370–377): Mark Sherlock and Paul M. Stewart
Chapter 49 Adrenal Causes of Cushing's Syndrome (pages 378–383): John R. Lindsay and A. Brew Atkinson
Chapter 50 Adrenal Incidentalomas (pages 384–389): Maria Verena Cicala, Pierantonio Conton, Anna Patalano and Franco Mantero
Chapter 51 Androgen?Secreting Tumors (pages 390–395): Quirinius Barnor, Tom R. Kurzawinski and Gerard S. Conway
Chapter 52 Functional Ovarian Tumors (pages 396–403): Nia Jane Taylor and Niall Richard Moore
Chapter 53 Endocrine Aspects of Ovarian Tumors (pages 404–411): John H. Shepherd and Lisa Wong
Chapter 54 Testicular Germ Cell Cancers (pages 412–420): R. Timothy D. Oliver
Chapter 55 Neoplasia and Intersex States (pages 421–429): Sabine E. Hannema and Ieuan A. Hughes
Chapter 57 Classification of Neuroendocrine Tumors (pages 435–442): Adeel Ansari, Karim Meeran and Stephen R. Bloom
Chapter 58 Imaging of Gastrointestinal Neuroendocrine Tumors (pages 443–454): Andrew F. Scarsbrook and Rachel R. Phillips
Chapter 59 Insulinomas and Hypoglycemia (pages 455–461): Adrian Vella and F. John Service
Chapter 60 Gastrinomas (Zollinger–Ellison Syndrome) (pages 462–468): Matthew L. White and Gerard M. Doherty
Chapter 61 VIPomas (pages 469–473): Vian Amber and Stephen R. Bloom
Chapter 62 Glucagonomas (pages 474–478): Niamh M. Martin, Karim Meeran and Stephen R. Bloom
Chapter 63 Somatostatinomas (pages 479–481): John A.H. Wass
Chapter 64 Lung and Thymic Neuroendocrine Tumors (pages 482–487): Dan Granberg and Kjell Oberg
Chapter 65 Carcinoid Syndrome (pages 488–497): Thorvardur R. Halfdanarson and Timothy J. Hobday
Chapter 66 Appendiceal and Hindgut Carcinoids (pages 498–501): Humphrey J. F. Hodgson
Chapter 67 Chemotherapy for Neuroendocrine Tumors (pages 502–504): Rebecca L. Bowen and Maurice L. Slevin
Chapter 68 Multiple Endocrine Neoplasia Type 1 (MEN 1) (pages 505–514): Cornelis J.M. Lips, Koen M.A. Dreijerink, Gerlof D. Valk and Jo W.M. Hoppener
Chapter 69 Medullary Thyroid Carcinoma and Associated Multiple Endocrine Neoplasia Type 2 (pages 515–522): Clive S. Grant
Chapter 70 von Hippel–Lindau Disease (pages 523–527): Shern L. Chew and Eamonn R. Maher
Chapter 71 Neurofibromatosis Type 1 (pages 528–531): Vincent M. Riccardi
Chapter 72 Carney Complex (pages 532–536): Constantine A. Stratakis
Chapter 73 McCune–Albright Syndrome (pages 537–544): William F. Schwindinger and Michael A. Levine
Chapter 74 Cowden Syndrome (pages 545–548): Ingrid Witters and Jean?Pierre Fryns
Chapter 75 Paraneoplastic Syndromes (pages 549–555): David William Ray
Chapter 76 Syndrome of Inappropriate Antidiuretic Hormone Secretion (pages 556–560): Rachel K. Crowley and Chris Thompson
Chapter 77 Hypercalcemia of Malignancy (pages 561–566): Gregory R. Mundy, Babatunde Oyajobi, Susan Padalecki and Julie A. Sterling
Chapter 78 Syndrome of Ectopic ACTH Secretion (pages 567–575): Marie?Laure Raffin?Sanson, Helene Fierrard and Xavier Bertagna
Chapter 79 Insulin?Like Growth Factors and Tumor Hypoglycemia (pages 576–581): Robert C. Baxter
Chapter 80 Metastatic and Other Extraneous Neoplasms in Endocrine Organs (pages 582–587): Ian D. Buley
Chapter 81 Endocrine Late Effects of Cancer Therapy (pages 588–598): Robert D. Murray
Chapter 82 Endocrine?Responsive Tumors: Prostate Cancer (pages 599–608): Sarah Ngan, Ana Arance and Jonathan Waxman
Chapter 83 Endocrine Therapy in Breast Cancer Management (pages 609–617): Andrew M. Wardley
Chapter 84 Female Reproductive Hormone Therapy: Risks and Benefits (pages 618–622): Toral Gathani, Jane Green and Valerie Beral