Climacteric Medicine-Where Do We Go? Proceedings of the 4th Workshop of the International Menopause Society

Book Cover......Page 1
Title......Page 4
Copyright......Page 5
Contents......Page 6
Foreword......Page 14
Introduction......Page 16
1 Menopause: lack of Darwinian adaptation drives its physiology......Page 19
2 A holistic approach to mature women’s health and aging......Page 24
3 Natural history of menopause studies and related efforts at the National Institute on Aging, NIH......Page 31
4 Major findings of the Melbourne Women’s Midlife Health Project......Page 42
5 The Women’s Health in the Lund Area (WHILA) study......Page 51
6 Adequately assessed quality of life......Page 64
7 Quality of life: the Asian perspective......Page 69
8 Alternatives to hormone therapy in menopausal women......Page 74
9 Women’s perspectives of hormone replacement therapy in Europe: country-specific aspects......Page 104
10 Recent clinical data and the role of menopausal hormone therapy today......Page 111
11 Impact on current clinical practice in Spain......Page 116
12 A clinician’s response to the WHI......Page 119
13 Pharmacology during the menopausal transition......Page 125
14 Some background considerations relevant to the evaluation of the effects of hormone therapy......Page 135
15 Menopausal medicine and its potential drug development opportunities......Page 137
16 Clinical background of prescribing tibolone......Page 141
17 Specific products for individual therapy......Page 145
18 Are all HRT preparations the same?......Page 151
19 Breast cancer risk: differences between hormone preparations?......Page 160
20 Observational studies and randomized controlled trials of hormone therapy: effect of stage of menopause on outcomes......Page 169
21 How representative are the results of the WHI for daily clinical decisions about hormone therapy in other regions of the world?......Page 175
22 Effects of HRT on the risks of breast cancer and cardiovascular disease: the validity of the epidemiological evidence......Page 181
23 WHI, HERS and other trials: consequences for clinical practice......Page 190
24 Do genes determine risk and benefits of hormone therapy?......Page 194
25 Hormone replacement therapy: new pharmacological and endocrinological approaches......Page 200
26 Future perspectives in hormone replacement therapy and menopause research......Page 213
27 Women’s health research: current priorities, future directions......Page 221
28 Natural history and progress of the menopause......Page 227
29 Recommendations for hormone therapy based on the Women’s Health Initiative......Page 231
30 What hormone preparations will be available?......Page 238
31 Guidelines for the hormone treatment of women in the menopausal transition and beyond......Page 241
Index......Page 246