Chronic Allograft Failure: Natural History, Pathogenesis, Diagnosis, and Management

Cover......Page 1
Contents......Page 6
Editor/Contributors......Page 11
Foreword......Page 18
Preface......Page 19
Acknowledgements......Page 20
1. Introducing Chronic Graft Failure......Page 21
2. Chronic Allograft Failure: Past, Present......Page 23
3. Solid Organ Transplantation—An Overview......Page 29
4. Analyzing Graft Failure in the Scientifi c Registry of Transplant Recipients: The Sources and Natureof the Data Available......Page 41
5. Th e Immunology of Chronic Allograft Injury......Page 49
6. Ischemia-Reperfusion Injury: Pathophysiology and Clinical Approach......Page 59
7. Heat Shock Protein 47 in Chronic Allograft Nephropathy......Page 68
8. Dendritic Cell-Based Approaches to Organ Transplantation......Page 73
9. Cardiac Allograft Vasculopathy......Page 83
10. Th e Pathology of Heart Allograft Rejection......Page 94
11. Experimental Gene Th erapy......Page 100
12. Th e Basic Science of Lung Allograft Failure......Page 107
13. Th e Role for Cytokine Responses in the Pathogenesis of Lung Allograft Dysfunction......Page 116
14. Diagnosis of Chronic Graft Failure after Lung Transplantation......Page 135
15. Treatment of Chronic Graft Failure after Lung Transplantation......Page 144
16. Liver Transplantation - An Overview......Page 155
17. Hepatic Allograft Loss: Pathogenesis,Diagnosis and Management......Page 162
18. Chronic Allograft Dysfunction - Liver......Page 167
19. Liver Graft Loss Due to Vascular Complications......Page 173
20. Late Allograft Failure: Liver......Page 179
21. Liver Allograft Failure Due to Recurrent Disease - Pathology......Page 184
22. Chronic Allograft Enteropathy......Page 190
23. Renal Allograft Survival: Epidemiologic Considerations......Page 196
24. Predictive Parameters of Renal Graft Failure......Page 207
25. Clinico-Pathological Correlations of Chronic Allograft Nephropathy......Page 215
26. Recurrent Glomerular Disease in the Allograft :Risk Factors and Management......Page 220
27. Pathology of Kidney Allograft Dysfunction......Page 242
28. Islet of Langerhans: Cellular Structure and Physiology......Page 249
29. Islet Transplantation......Page 253
30. Metabolic Indicators of Islet Graft Dysfunction......Page 263
31. Pancreas and Islet Allograft Failure......Page 267
32. Chronic Pancreas Allograft Failure......Page 272
33. Pathological Aspects of Pancreas Allograft Failure......Page 278
34. Th e Graft : Emerging Viruses in Transplantation......Page 287
35. Cytomegalovirus and Allograft Failure after Solid Organ Transplantation......Page 298
36. Hepatitis C Virus Infection as a Risk Factor for Graft Loss after Renal Transplantation......Page 308
37. Polyomavirus Type BK-Associated Nephropathy and Renal Allograft Graft Loss: Natural History, Patho-Physiology, Diagnosis and Management......Page 315
38. Polyomavirus Allograft Nephropathy: Clinico-Pathological Correlations......Page 326
39. Pharmacotherapeutic Options in Solid Organ Transplantation......Page 339
Index......Page 354