Chlorodioxins: Origin and Fate (Advances in Chemistry Series : No 120)

Half Title......Page 1
Title......Page 3
Copyright......Page 4
Series Information......Page 5
FOREWORD......Page 6
PREFACE......Page 7
Literature Cited......Page 8
1 
The Preparation of Uniformly Labeled 
14
C-2,7-Dichlorodibenzo-p-dioxin and 
14
C-2,3,7,8-Tetrachlorodibenzo-p-dioxin......Page 9
Mass Spectrometry......Page 13
Literature Cited......Page 14
Designation, Chromatographic Separation, and Analysis......Page 15
Unlabeled Chemicals......Page 16
Labeled Chemicals......Page 19
Discussion......Page 20
Literature Cited......Page 21
3 
X-ray Diffraction Studies of Chlorinated Dibenzo-p-dioxins......Page 22
Literature Cited......Page 33
4 
Thermal Chemistry of Chlorinated Phenols......Page 34
Literature Cited......Page 40
5 
Cation Radicals of Chlorinated 
Dibenzo-p-dioxins......Page 41
Literature Cited......Page 51
6 
Photochemistry of Dibenzo-p-dioxins......Page 52
The Photolysis of Dioxins......Page 54
Photochemical Generation of Dioxins......Page 58
Discussion......Page 60
Literature Cited......Page 61
7 
Toxicology of Chlorinated 
Dibenzo-p-dioxins......Page 63
Acute Lethality......Page 64
Rabbit Ear Bioassay for Acnegenic Activity......Page 65
Chick Bioassay for Chick Edema Factor......Page 66
Rabbit Eye Irritation......Page 67
Teratogenicity......Page 68
Chick Edema Bioassay......Page 72
Discussion and Summary......Page 74
Literature Cited......Page 77
8 
Polychlorodibenzo-p-dioxins: Perinatal 
Effects and the Dominant Lethal Test in 
Wistar Rats......Page 78
Experimental......Page 79
PRENATAL EFFECTS......Page 80
POSTNATAL EFFECTS......Page 82
LOCALIZATION OF 14
C-2,3,7,8-TETRACHLORODIRENZO- p -DIOXIN IN TIS­
SUES OF PREGNANT RATS .......Page 83
DOMINANT LETHAL ASSAY.......Page 85
l,2,3,4-Tetrachlorodibenzo-£-Dioxin.......Page 86
2-Chlorodibenzo-£-Dioxin.......Page 87
Conclusion......Page 90
Literature Cited......Page 91
9 
Excretion and Tissue Distribution of 
2,3,7,8-Tetrachlorodibenzo-p-dioxin in the 
Rat......Page 93
Results......Page 94
Discussion......Page 97
Literature Cited......Page 98
10 
An Improved Analysis for 
Tetrachlorodibenzo-p-dioxins......Page 100
Acknowledgment......Page 111
Literature Cited......Page 112
11 
Environmental Significance of Chlorodioxins......Page 113
Mobility......Page 114
Persistence......Page 115
Plant Uptake......Page 117
Summary......Page 118
Literature Cited......Page 119
12 
Dioxin Residues in Lakeland Sand and Bald 
Eagle Samples......Page 120
Materials and Methods......Page 121
Results and Discussion......Page 122
Literature Cited......Page 126
13 
The Stability of Pentachlorophenol and 
Chlorinated Dioxins to Sunlight, Heat, and 
Combustion......Page 127
Light Stability of Sodium Pentachlorophenate......Page 128
Effects of Combustion and Heat......Page 129
Effect of UV Radiation on Sodium Pentachlorophenate......Page 130
Effect of U V Irradiation and Air Oxidation on Chlorinated Dibenzo-
p-dioxin......Page 131
Conclusion......Page 132
14 
Preparation of Chlorodibenzo-p-dioxins 
for Toxicological Evaluation......Page 134
Discussion......Page 135
Preparation of the Copper (Ullmann) Catalyst......Page 138
2-Bromo-3,4,6-trichlorophenol.......Page 139
2.8- Dichlorodibenzo-p-dioxin......Page 140
Hexachlorodibenzo-p-dioxin.......Page 141
Octachlorodibenzo-p-dioxin......Page 142
Literature Cited......Page 143
INDEX......Page 145