Chemotherapy: Cancer Chemotherapy II

Front Matter....Pages i-xviii
On the Cytogenetic Criteria of Rational Tumor Chemotherapy....Pages 1-3
Life Prolongation of Mice Bearing Syngeneic Tumor, Leukemia P388 with the Streptococcal Preparation, OK-432 and Its Mechanism of Action....Pages 5-8
Breakdown of Non-immune Metastasis Resistance after Cytostatic Drugs....Pages 9-10
Prevention of Lymphoma Growth in Mice by a Covalent Drug-Carrier-Antibody Complex....Pages 11-16
Effects of Anti-DNA and Anti-RNA Antibodies Bound to Melphalan and Methotrexate on C3H Mammary Adenocarcinoma and L 1210 Leukaemia....Pages 17-20
Immunosuppressive Effects of Some Organic Compounds with Anti-Inflammatory Activity....Pages 21-26
Differential Immunosuppressive Effects of Anticancer Agents on Lymphoid Subpopulations....Pages 27-30
Experiments and Theoretical Considerations on Synchronisation of L 1210 Ascites Tumour Cells and Crypt Epithelia of the Mouse with Vincristine....Pages 31-36
Theoretical Bases for Designing Combination Therapy with Dibromodulcitol (DBD)....Pages 37-42
Tilorone HYdrochloride: Its Pharmacokinetic Parameters and Its Pharmacodynamic Effects....Pages 43-50
Pharmacokinetics of Futraful (FT-207) for Clinical Application....Pages 51-57
Effects of Cytotoxic Drugs and/or Corticosteroids on Peripheral Leukocytes....Pages 59-62
The Effectiveness of Sequential Therapy Schedules with Adriamycin and Cyclophosphamide in the P388 Leukemia Model....Pages 63-76
Antitumor Activity of Mimosine and Mimosine HYdrochloride against B16 Melanoma in BDF Mice....Pages 77-85
A New Multipeptide Antitumour Drug....Pages 87-89
Metabolism of the Tumour-Inhibitory 3.3-Dimethyl-1-Phenyl-Triazene and Its 4-Chlorophenyl Analogue....Pages 91-96
Antitumour Activity of Benzofuroxan Derivatives....Pages 97-101
Antitumour Activity of Tetrazolopyridazines and Tetrazolophthalazines....Pages 103-106
Antineoplastic Effect of Compound 9777-VUFB in Animals with Experimental Tumours; Its Interaction with Some Cutostatics....Pages 107-113
Effects of GP 48 989 Alone and in Combination with Hormones and Chemotherapeutic Agents on DMBA-Induced Mammary Carcinomata II....Pages 115-119
R 17934 : A New Synthetic Anti-cancer Drug Interfering with Microtubules....Pages 121-128
Antitumour Activity of Carminomycin....Pages 129-132
Variamycin, A New Antitumour Antibiotic....Pages 133-138
Inhibition by Caffeine of Post-Replication DNA Repair in Hamster Cells Treated with CIS Platinum (II) Diamine Dichloride....Pages 139-144
The Role of nuclear proteins in the chemotherapeutic effect of Dibromodulcitol (DBD)....Pages 145-151
The Effect of Dibromodulcitol on the Replication of DNA in Yoshida Sarcoma Cells....Pages 153-158
Clinical Cancer Chemotherapy with Drugs Aimed at Gene Regulators....Pages 159-164
Characterization of the Bleomycin Action on DNA....Pages 165-168
Antitumor Antibiotic Carminomycin: Mechanism of Action....Pages 169-173
Effect of Combined Chemotherapy with Lysosome Labilizers and Mitomycin-C....Pages 175-183
Optimal Conditions for Tumor Chemotherapy Chosen on the Basis of Changes in the Lipid Antioxidant Activity....Pages 185-190
An Antitemplate Approach to Develop Selective Inhibitors of Oncornaviral Reverse-Transcriptase....Pages 191-196
Experimental Approach to Increase the Effects of Cancer Chemotherapy in Tumor-Bearing Rats Pretreated with an Inducer on Microsomal Drug-Metabolizing Enzyme (cytochrome p-450)....Pages 197-202
Effect of the Drug-Metabolizing Enzyme Inducers on the Cytostatic Activity of Dibromodulcitol....Pages 203-208
Studies of N-Methyl-N-Nitrosourea-C 14 O Pharmacokinetics in Mice with Hepatoma 22A....Pages 209-213
Collateral Sensitivity between an Alkylating Agent and Halogenated Methotrexate....Pages 215-218
Meso-1,2-bis-(3,5-Dioxopiperazine-1-Yl) -1,2-Dimethyl-ethane (ICRF 193): A Potent Antitumour Analogue of ICRF 159....Pages 219-220
New Derivatives of Nitrosourea with a High Therapeutic Index for Oncostatism and Immunosuppression....Pages 221-228
Effect on L1210 Leukemia, on Antibody Forming Cells, and on Macrophage Cytotoxicity of Ellipticine and 3 Derivatives....Pages 229-235
Antitumor Activity of Daunorubicin Derivatives....Pages 237-241
New Antitumour Analogues of Cytosine Arabinoside and the Effect against Mouse Leukemia L1210....Pages 243-248
Exceptional Responses to Chemotherapy and/or Hormonotherapy of Cases with Generalized Cancer....Pages 249-255
Clinical Considerations in Myelomatosis....Pages 257-264
Chronic Gastritis, Atypical Epithelia in Biopsies and Therapeutic Consequences....Pages 265-268
Clinical Studies on Changes in Serum Glycoproteins in Cancer Chemotherapy....Pages 269-274
Double-Blind Trial with Levamisole in Resectable Lung Cancer....Pages 275-280
Carcino-Embryonic Antigen Determinations and Chemotherapy in Cancer Patients....Pages 281-285
Aspects of Chemo-Immunotherapy in a Controlled Clinical Study for the Treatment of Bronchogenic Cancer....Pages 287-293
Pulse-Cytophotometric Monitoring of the Intensive Chemotherapy of Acute Leukaemia....Pages 295-303
Treatment of Adenocarcinoma of the Ovary with Combined Immunotherapy and Chemotherapy....Pages 305-311
Clinical and Experimental Studies on Immunochemotherapy Using OK-432, A New Streptococcal Preparation....Pages 313-318
Phase I and Phase II Studies in the Treatment of Cancer Patients by Radiotherapy, Chemotherapy and Methanol Extraction Residue of an Anti-Tuberculosis Vaccine (MER)....Pages 319-325
Additional Therapy with Trenimon in Treatment of Carcinoma of the Uterine Cervix....Pages 327-329
Interferences of Radiotherapy and Chemotherapy on the Binding of 3 H-17β-Oestradiol with Its Specific Receptors....Pages 331-337
Mechanism of Antitumor Action of Hemolytic Streptococcal Preparation OK-432 (NSC-B116209) for Malignant Pleural or Peritoneal Effusion by Intrathoracal and Intraperitoneal Injection....Pages 339-344
The Significance of Reduction Surgery in the Treatment of Advanced Cancer Patients....Pages 345-354
Intermittent Longterm Polychemotherapy as an Adjuvant to Surgery of Bronchogenic Carcinoma....Pages 355-360
Polychemotherapy for Advanced Lung Carcinoma: Clinical Results and Further Consequences....Pages 361-366
Chemotherapy in Conservative Treatment of Lung Cancer Patients....Pages 367-373
Effective Chemotherapy for Bronchial Carcinoma....Pages 375-380
MUltidisciplinary Curative Assault on Disseminated Carcinoma of the Breast....Pages 381-386
Potentiation of Drugs Using Sequential Chemotherapy Against Disseminated Breat, Bronchial and Central Nervous System Solid Tumors....Pages 387-404
Animal and Human Studies with Oral Mitomycin C(6): A Preliminary Report....Pages 405-411
Chemohormonal Therapy of Breast Cancer — A Pilot Phase I–II Study....Pages 413-420
The Results of Bleomycin Treatment in 90 Patients with Malignant Disease....Pages 421-423
CIS-Platinum Diamminodichloride in the Treatment of Squamous Cell Carcinoma and Other Malignant Diseases....Pages 425-434
Anhydro-Arabinosyl-Fluorocytosine Hydrochloride: A Phase I Study....Pages 435-435
Ifosfamide in the Treatment of Lung Cancer and Metastases of Solid Malignant Tumours....Pages 437-444
Preclinical and Phase-I Studies of Ifosfamide for Its Massive Dose Cumulation Schedule....Pages 445-450
Clinical Pharmacological Studies with Formyl-Leurosin in Malignant Diseases....Pages 451-456
Clinical Investigations with F-Leurosine....Pages 457-462
Clinical Investigations of Dibromodulcitol in the Treatment of Malignant Diseases....Pages 463-468
Oral Estracyt ® (Estramustine Phosphate) in the Treatment of Advanced Carcinoma of the Prostate....Pages 469-473
Treatment of Prostatic Carcinoma with Estracyt (Estramustine Phosphate)....Pages 475-479
Clinical Use of DDMP in Cancer Chemotherapy....Pages 481-483
Combination of Anticoagulants and Antineoplastic Drugs in Cancer Chemotherapy....Pages 485-490
Adriamycin Cardiotoxicity in Man: Effect of Pretreatment with Beta-Methyldigoxin. A Poligraphic Study....Pages 491-499
Combination of Adriamycin and Bleomycin in the Treatment of Advanced Cervical Cancer....Pages 501-505
Treatment of Chemotherapy Resistant Nonseminomatous Testicular Tumors with DDP (NSC-119875)....Pages 507-512
Combination Chemotherapy of Advanced Hodgkin’s Disease with Adriamycin, DTIC, CCNU, and Bleomycin....Pages 513-516
Proteolytic Enzymes in the Treatment of Malignant Pleural Effusions and Solid Metastases....Pages 517-521
Intra-Arterial Chemotherapy of Head and Neck Squamous Cell Carcinoma....Pages 523-528
Chemotherapy of Glioblastoma Multiforme: A Statistical Analysis of Its Effect....Pages 529-533
1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in the Treatment of Primary Central Nervous System Tumors....Pages 535-540
BCNU and CCNU Chemotherapy of Tumours of the Central Nervous System....Pages 541-549
Combination Chemotherapy and CCNU Treatment of Glioblastoma: A Comparative Trial....Pages 551-556
Combination of Adriamycine, VM 26, Cyclophosphamide & Prednisone (AVmCP) in Chemotherapy of Lympho & Reticulum Cell Sarcoma (Stages & Topographic Forms III & IV)....Pages 557-567
Comparison of the Combinations a) PDN + VCR°, b) PDN + VCR° → ADM x , c) PDN + VCR° → ADM x → CAR x ; and d) PDN + VCR + ASP° in Induction of First Remission of Acute Lymphoid Leukemia....Pages 569-574
Clinical Evaluation of Peptichemio in Some Hemoblastoses and Solid Tumours....Pages 575-579
Chemotherapeutic Management of Non-Hodgkin’s Lymphoma: Comparative Study of Various Combinations....Pages 581-583
Chemotherapy for Gastric and Colorectal Carcinoma by Intra-Aortic Infusion....Pages 585-590
Effect of Adjuvant Chemotherapy with Mitomycin C on the Recurrence of Gastric Cancer after Radical Surgery....Pages 591-595
Long-Term Cancer Chemotherapy for Stage III to IV Gastric Cancer Following Non-Curative Resection....Pages 597-603
Chemotherapy for Advanced Ovarian Malignancy....Pages 605-609
Changes in Clinical and Histological Patterns Observed in Patients with Advanced Carcinoma of the Ovary Treated with Progesterone....Pages 611-614
Back Matter....Pages 615-618