Cerebral Ischemia and Hemorheology

Front Matter....Pages I-XIII
Local Control of the Cerebral Circulation....Pages 1-12
Neurogenic Control of Cerebral Circulation....Pages 13-23
Front Matter....Pages 25-25
Hemorheology and Cerebral Infarction: On the Role of Pathological Blood Thixotropy in the Pathogenesis of and Therapy for States of Acute Cerebral Hypoperfusion....Pages 27-50
Blood Cells and the Control of the Circulation....Pages 51-56
The Role of White Blood Cells in the Control of Blood Rheology....Pages 57-68
Hemorheological Disorders in Cerebrovascular Accident: Relationship to Inflammatory Processes and Thrombogenesis....Pages 69-75
Pathophysiology of Blood Rheology in Ischemic Diseases....Pages 76-79
Studies on the Mechanisms of Shear-Induced Platelet Activation....Pages 80-89
Filterability and the Shape of Platelets: The Effect of Stimulant....Pages 90-95
Complex Microvascular Effects Involving Plasma and Red Cell Movement in Brain Following Alterations of Viscosity....Pages 96-101
Fluid Dynamics, The Factor VIII/vWF Complex, and Thrombosis on Vessel Walls....Pages 102-112
Blood Viscosity and Platelet Functions During Cerebrovascular Accidents....Pages 113-120
Blood Coagulation and Anticoagulation in Ischemic Stroke....Pages 121-130
Concerning the Influence of Hematocrit and Red Blood Cell Aggregation on Blood Viscosity In Vivo....Pages 131-142
Microrheological Studies of the Effects of Intraerythrocytic Parasites on Red Cell Deformability....Pages 143-153
Effects of Leukocytes on Microvascular Rheology....Pages 154-160
Front Matter....Pages 161-161
Biochemical Aspects of Cerebral Ischemia as Related to Age....Pages 163-172
Patterns of Ischemic Injury to the Brain: The Influence of Local Hemodynamic Factors....Pages 173-185
Improved Measurement of Regional Glucose Metabolism by Individual Determination of the Lumped and Kinetic Constants in Stroke Patients....Pages 186-201
Estimation of Local Cerebral Hematocrit with Positron Emission Tomography and Single Photon Emission Computed Tomography....Pages 202-209
Front Matter....Pages 161-161
Regional Cerebral Blood Flow, Volume, and Hematocrit Measured by Single Photon Emission Computed Tomography....Pages 210-216
Mechanisms of Ischemic Cell Swelling in the Brain....Pages 217-221
Rheological Behavior of Platelets in Situ in Middle Cerebral Artery Occlusion....Pages 222-232
Regional Hemodynamic and Metabolic Disturbances in Experimental Cerebral Ischemia....Pages 233-240
Reducing Cellular Energy Requirements as Protection Against CNS Ischemia....Pages 241-248
Biochemical Aspects of Cerebral Ischemia....Pages 249-256
Leukotrienes, Prostaglandins, and Granulocyte Accumulation in Cerebral Ischemia....Pages 257-265
Baseline Hemodynamic State and Response to Hemodilution in Patients with Acute Cerebral Ischemia....Pages 266-271
Arachidonic Acid Metabolism in Cerebral Ischemia....Pages 272-279
Effect of Hemodynamic Shear on Arachidonic Acid Metabolism of Vascular Endothelium....Pages 280-289
Cerebral Blood Flow and Energy Metabolism in Severe Subarachnoid Hemorrhage in the Cat: Effect of Calcium Antagonist Vasodilation....Pages 290-293
Front Matter....Pages 295-295
The Effect of Brain Edema on the Microcirculation....Pages 297-300
Blood Viscosity and Cerebral Blood Flow....Pages 301-305
Hemorheological and Perihemorheological Aspects of the Vessel-Blood Organ Affecting Ischemia....Pages 306-314
Viscosity Effects on Blood Flow Dynamics: Influence of Isovolemic Hemodilution on Focal Cerebral Ischemia....Pages 315-325
Focal and Remote Dysmetabolism in Stroke....Pages 326-333
Clinical Aspects of Reversible Cerebral Ischemia....Pages 334-341
An Autoradiographic Study of Plasma Skimming in Cerebral Ischemia....Pages 342-348
Defective Serum PGI 2 Binding in Thrombotic Stroke: A Potential Mechanism for Platelet Hyperaggregability in Stroke....Pages 349-355
Relationships Between Viscosity Factors and Cerebral Blood Flow and Porous Bed Viscometry in Normals and Stroke Prone Subjects....Pages 356-361
Front Matter....Pages 295-295
Comparisons of Regional Topography and Flow Reactivity in Cerebral Ischemic Boundary Zones....Pages 362-365
Chronic Platelet Abnormalities in TIA Patients....Pages 366-370
The Rheological Effect of Fluosol FC 43 on Focal Cerebral Ischemia in the Rat....Pages 371-376
Intravascular RBC Aggregation and Transient Diminution of Cerebrovascular Volume Following Middle Cerebral Artery Occlusion in Cats....Pages 377-385
Clinical and Experimental Evidence of Microthrombosis in Cerebral Ischemia....Pages 386-393
Effect of Hemodilution on Cerebral Ischemia Caused by Intracranial Hypertension....Pages 394-397
Effect of Hydroxyethyl Starch and Low Molecular Weight Dextran on Cerebral Blood Flow and Hemorheology in Normal Baboons....Pages 398-407
Front Matter....Pages 409-409
The Role of Hemodilution in the Management of Cerebral Ischemia....Pages 411-415
Hemodilution in Cerebral Infarction....Pages 416-422
Effect of Hemodilution on Regional Cerebral Blood Flow in Patients with Acute Cerebral Infarction....Pages 423-428
Hypervolemic Hemodilution with 10% HES 200/0.5 and 10% Dextran 40 in Patients with Ischemic Stroke....Pages 429-435
Glycerol and Rheomacrodex in the Treatment of the Acute Ischemic Insult: A Placebo-Controlled Double-Blind Trial....Pages 436-444
Hemorheological Abnormalities in Acute Cerebral Ischemia....Pages 445-451
Do Hemorheological Properties Influence Vasomotor Reactivity of the Brain Arteries? A Transcranial Doppler Study During Hypo-, Normo- and Hypercapnia....Pages 452-458
Effect of Pentoxifylline on Cortical pO 2 in Cat and Human Brain....Pages 459-463
No-Reflow in the Microcirculation. The Granulocyte Tragedy....Pages 464-471
Multicenter Trial of Hemodilution in Acute Ischemic Stroke....Pages 472-486
Similar and Opposite Hemorheological Effects of Dextran 40 and Hydroxyethyl Starch in Hemodilution Therapy for Stroke....Pages 487-495
Prognostic Importance of Blood Rheology in Acute Stroke....Pages 496-501
Hemispheric Cerebral Blood Flow Changes with Hypervolemic Hemodilution Using Pentastarch After Acute Stroke....Pages 502-507
Front Matter....Pages 409-409
The Role of Blood Components and Their Properties in the Pathogenesis of Cerebral Infarction of Cortical and Deep Brain Structures — Platelet Aggregability....Pages 508-513
Some Rheological Considerations in Ischemic Cerebrovascular Disease — Blood Viscosity, RBC Aggregation, and RBC Zeta Potential....Pages 514-519
Hemorheological Abnormalities as Physicochemical Risk Factors for Cerebral Infarction....Pages 520-527
Hemorheological Changes in Patients with Cerebral Ischemia: Differences in Comparison with Other Vascular Disorders....Pages 528-533
Back Matter....Pages 535-539