Cardiovascular physiology

Hematology A Pathophysiologic Approach
Prelims
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Title page
Copyright page
Dedication
PREFACE
ACKNOWLEDGMENTS
Table of contents
Brief Overview of the Hematolymphoid System
	Key Words and Concepts
Chapter 1: Hematopoiesis
	Key Points
	Key Words and Concepts
	Technical Considerations
Chapter 2: Erythropoiesis and Oxygen Transport
	Key Points
	Key Words and Concepts
	Oxygen Transport
Chapter 3: Iron, Heme, and Hemoglobin
	Key Points
	Key Words and Concepts
	Iron Deficiency Anemia
	Heme
	Hemoglobin
	Oxygen Affinity
Chapter 4: Hemoglobinopathy
	Key Points
	Key Words and Concepts
	Non-Functional Hemoglobin Variants
	Beta Globin Mutations
	Thalassemia
	Unstable Hemoglobin Variants
Chapter 5: Red Blood Cell Metabolism and Enzyme Defects
	Key Points
	Key Words and Concepts
	Red Blood Cell Enzyme Defects
Chapter 6: Hemolytic Anemia
	Key Points
	Key Words and Concepts
	Extrinsic Hemolytic Anemia
	Intrinsic Hemolytic Anemia
Chapter 7: Aplastic Anemia and Related Disorders
	Key Points
	Key Words and Concepts
	Anemias Associated with Non-Hematopoietic Organ Dysfunction
Chapter 8: Megaloblastic Anemia
	Key Points
	Key Words and Concepts
Chapter 9: Myeloid Cells
	Key Points
	Key Words and Concepts
	Neutrophils
	Eosinophils
	Basophils and Mast Cells
	Monocytes
Chapter 10: Immune System and Related Disorders
	Key Points
	Key Words and Concepts
	Immunoglobulin Structure and Function
	T CELL RECEPTOR SIGNALING
	T Cell Subsets
	Immunodeficiency
	Lymphoid Tumors
Chapter 11: Genetic Basis of Hematologic Neoplasia
	Key Points
	Key Words and Concepts
	Cell Proliferation
	Apoptosis
	Specific Genetic Defects in Hematologic Cancer
	Molecular and Cytogenetic Techniques
Chapter 12: Leukemia and Related Disorders
	Key Words and Concepts
	Introduction
	Acute Myeloid Leukemia
	Acute Lymphoblastic Leukemia
	Chronic Lymphoid Leukemia
	Myelodysplastic Syndromes
	Myeloproliferative Disorders
	Myelodysplastic Syndromes/Myeloproliferative Diseases
Chapter 13: Lymphoma and Related Disorders
	Key Points
	Key Words and Concepts
	B Cell Non-Hodgkin Lymphoma
	T or Natural Killer Cell Non-Hodgkin Lymphoma
	Hodgkin Lymphoma
	Classic Hodgkin Lymphoma
	Histiocytic and Dendritic Cell Neoplasms
Chapter 14: Blood Coagulation
	Key Points
	Key Words and Concepts
	Blood Coagulation
	Fibrinolysis
	Bleeding Disorders
	Hereditary Thrombophilia
	Anticoagulation
	Coagulation Testing
Chapter 15: Platelets
	Key Points
	Key Words and Concepts
	Thrombocytopenia and Thrombocytosis
	Platelet Function Defects
Chapter 16: Benign Conditions of Lymphoid Organs
	Key Points
	Key Words and Concepts
	Spleen
	Thymus
Chapter 17: Blood Transfusion and Stem Cell Transplantation
	Key Points
	Key Words and Concepts
	Blood Transfusion
	Blood Groups
	Transfusion Reactions
	Stem Cell Transplantation
	Complications Of Allogeneic Stem Cell Transplantation
	Human Leukocyte Antigens
Chapter 18: Cancer Chemotherapy
	Key Points
	Key Words and Concepts
	Cell-Cycle Active Agents
	Non-Cell-Cycle Active Agents
APPENDIX A: Complete Blood Count
	Age and Pregnancy Related Hematologic Changes
	Age and Pregnancy Related Coagulation Changes
	Key Words and Concepts
APPENDIX B: Some Useful Immunophenotypic Markers for Hematologic Diagnosis
Index
Color plates