Cardiac Electrophysiology: From Cell to Bedside

Content: 
Front Matter, Page i
Copyright, Page ii
Contributors, Pages iii-xvi
Preface, Page xvii
Video Contents, Page xxvi
1 - Voltage-Gated Sodium Channels and Electrical Excitability of the Heart, Pages 1-11
2 - Calcium Channels in the Heart, Pages 13-22
3 - Voltage-Regulated Potassium Channels, Pages 23-32
4 - Structural and Molecular Bases of Cardiac Inward Rectifier Potassium Channel Function, Pages 33-41
5 - Mammalian Calcium Pumps in Health and Disease, Pages 43-53
6 - Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function, Pages 55-69
7 - Structural and Molecular Bases of Mitochondrial Ion Channel Function, Pages 71-84
8 - Molecular Organization, Gating, and Function of Gap Junction Channels, Pages 85-94
9 - Biophysics of Normal and Abnormal Cardiac Sodium Channel Function, Pages 95-101
10 - Regulation of Cardiac Calcium Channels, Pages 103-113
11 - KCNQ1/KCNE1 Macromolecular Signaling Complex: Channel Microdomains and Human Disease, Pages 115-120
12 - Structural Determinants and Biophysical Properties of hERG1 Channel Gating, Pages 121-128
13 - Molecular Regulation of Cardiac Inward Rectifier Potassium Channels by Pharmacologic Agents, Pages 129-137
14 - Cardiac Stretch–Activated Channels and Mechano-Electric Coupling, Pages 139-149
15 - Biophysical Properties of Gap Junctions, Pages 151-160
16 - Excitation-Contraction Coupling, Pages 161-169
17 - Ion Channel Trafficking in the Heart, Pages 171-178
18 - Macromolecular Complexes and Regulation of the Sodium Channel Nav1.5, Pages 179-188
19 - Calmodulin and CaMKII as Ca2+ Switches for Cardiac Ion Channels, Pages 189-195
20 - Macromolecular Complexes and Cardiac Potassium Channels, Pages 197-204
21 - Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias, Pages 205-214
22 - The Intercalated Disc: A Molecular Network That Integrates Electrical Coupling, Intercellular Adhesion, and Cell Excitability, Pages 215-227
23 - Scaffolding Proteins and Ion Channel Diseases, Pages 229-234
24 - Epigenetics in Cardiac Rhythm Diseases, Pages 235-241
25 - Cardiac Impulse Is Initiated by a Coupled System of Membrane Ion Channels and Ca2+ Cycling Proteins, Pages 243-252
26 - Biological Pacing, Pages 253-263
27 - Intercellular Communication and Impulse Propagation, Pages 265-274
28 - Mechanisms of Atrioventricular Nodal Excitability and Propagation, Pages 275-285
29 - Cell Biology of the Specialized Cardiac Conduction System, Pages 287-296
30 - Cardiac Fibroblasts and Arrhythmogenesis, Pages 297-308
31 - Ionic Mechanisms of Atrial Action Potentials, Pages 309-318
32 - Models of the Ventricular Action Potential in Health and Disease, Pages 319-330
33 - Calcium Signaling in Cardiomyocyte Models With Realistic Geometries, Pages 331-340
34 - Theory of Rotors and Arrhythmias, Pages 341-350
35 - Supraventricular Arrhythmias in a Realistic 3D Model of the Human Atria, Pages 351-359
36 - Cardiac Electromechanical Models, Pages 361-369
37 - CaV1.2 and β-Adrenergic Regulation of Cardiac Function, Pages 371-381
38 - Cholinergic and Constitutive Regulation of Atrial Potassium Channel, Pages 383-391
39 - Pulmonary Vein Ganglia and the Neural Regulation of the Heart Rate, Pages 393-398
40 - Neural Activity and Atrial Tachyarrhythmias, Pages 399-407
41 - Sympathetic Innervation, Denervation, and Cardiac Arrhythmias, Pages 409-417
42 - Dominant Frequency and the Mechanisms of Initiation and Maintenance of Atrial Fibrillation, Pages 419-432
43 - Rotors in Human Atrial Fibrillation, Pages 433-442
44 - Atrial Ischemia and Fibrillation, Pages 443-448
45 - The Molecular Pathophysiology of Atrial Fibrillation, Pages 449-458
46 - Myofibroblasts, Cytokines, and Persistent Atrial Fibrillation, Pages 459-467
47 - Role of the Autonomic Nervous System in Atrial Fibrillation, Pages 469-474
48 - Mechanisms of Ventricular Tachycardia and Fibrillation, Pages 475-482
49 - Genetics of Atrial Fibrillation, Pages 483-490
50 - Mechanisms in Heritable Sodium Channel Diseases, Pages 491-500
51 - Inheritable Potassium Channel Disease, Pages 501-509
52 - Genetics and Cellular Mechanisms of the J Wave Syndromes, Pages 511-519
53 - Inheritable Phenotypes Associated With Altered Intracellular Calcium Regulation, Pages 521-528
54 - Pharmacologic Bases of Antiarrhythmic Therapy, Pages 529-540
55 - Pharmacogenomics of Cardiac Arrhythmias, Pages 541-547
56 - Optogenetic Control of Heart Muscle, Pages 549-557
57 - Cell Therapy and Regenerative Electrophysiology, Pages 559-566
58 - Assessment of the Patient With a Cardiac Arrhythmia, Pages 567-573
59 - Differential Diagnosis of Narrow and Wide Complex Tachycardias, Pages 575-580
60 - Mapping and Imaging, Pages 581-593
61 - CT and MRI for Electrophysiology, Pages 595-603
62 - Intracardiac Echocardiography for Electrophysiology, Pages 605-612
63 - Exercise-Induced Arrhythmias, Pages 613-619
64 - Cardiac Monitoring: Short- and Long-Term Recording, Pages 621-627
65 - Electrocardiographic Imaging in Patients With Acute Coronary Syndrome, Pages 629-635
66 - Head-up Tilt Table Testing, Pages 637-648
67 - Autonomic Testing and Cardiac Risk, Pages 649-656
68 - Monophasic Action Potential Recording, Pages 657-663
69 - T Wave Alternans, Pages 665-676
70 - Noninvasive Electrocardiographic Imaging of Human Ventricular Arrhythmias and Electrophysiological Substrate, Pages 677-684
71 - Genetic Testing, Pages 685-690
72 - Sinus Node Abnormalities, Pages 691-697
73 - Atrial Tachycardia, Pages 699-722
74 - Typical and Atypical Atrial Flutter: Mapping and Ablation, Pages 723-737
75 - Atrial Fibrillation: Paroxysmal, Persistent, and Permanent, Pages 739-754
76 - Preexcitation, Atrioventricular Reentry, and Variants, Pages 755-765
77 - Electrophysiological Characteristics of Atrioventricular Nodal Reentrant Tachycardia: Implications for the Reentrant Circuits, Pages 767-787
78 - Atrial Tachyarrhythmias in Adults With Congenital Heart Disease, Pages 789-799
79 - Junctional Tachycardia, Pages 801-807
80 - Premature Ventricular Complexes, Pages 809-813
81 - Outflow Tract Ventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management, Pages 815-825
82 - Fascicular Ventricular Arrhythmias, Pages 827-833
83 - Bundle Branch Reentry Tachycardia, Pages 835-847
84 - Ischemic Heart Disease, Pages 849-857
85 - Ventricular Tachycardia in Patients With Dilated Cardiomyopathy, Pages 859-871
86 - Ventricular Arrhythmias in Hypertrophic Cardiomyopathy, Pages 873-883
87 - Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy, Pages 885-894
88 - VTs in Catecholaminergic Cardiomyopathy (Catecholaminergic Polymorphic Ventricular Tachycardia), Pages 895-902
89 - Ventricular Arrhythmias in Heart Failure, Pages 903-912
90 - Ventricular Tachycardia in Noncompaction Cardiomyopathy, Pages 913-918
91 - Ventricular Arrhythmias in Takotsubo Cardiomyopathy, Pages 919-924
92 - Brugada Syndrome 1992–2012: Twenty Years of Scientific Progress, Pages 925-933
93 - Long and Short QT Syndromes, Pages 935-946
94 - Andersen-Tawil Syndrome, Pages 947-952
95 - Timothy Syndrome, Pages 953-957
96 - J Wave Syndromes, Pages 959-965
97 - Idiopathic Ventricular Fibrillation, Pages 967-973
98 - Sudden Infant Death Syndrome, Pages 975-979
99 - Sudden Cardiac Death in Adults, Pages 981-991
100 - Arrhythmias in Patients With Neurologic Disorders, Pages 993-999
101 - Drug-Induced Ventricular Tachycardia, Pages 1001-1008
102 - Ventricular Arrhythmias in Congenital Heart Disease, Pages 1009-1019
103 - Syncope, Pages 1021-1027
104 - Postural Orthostatic Tachycardia Syndrome, Pages 1029-1034
105 - Progressive Conduction System Disease, Pages 1035-1042
106 - Atrioventricular Block, Pages 1043-1049
107 - Sex Differences in Arrhythmias, Pages 1051-1059
108 - Sudden Cardiac Deaths in Athletes, Including Commotio Cordis, Pages 1061-1072
109 - Arrhythmias in Pediatric Population, Pages 1073-1086
110 - Sleep-Disordered Breathing and Arrhythmias, Pages 1087-1093
111 - Standard Antiarrhythmic Drugs, Pages 1095-1110
112 - New Antiarrhythmic Drugs and New Concepts for Old Drugs, Pages 1111-1119
113 - Impact of Nontraditional Antiarrhythmic Drugs on Sudden Cardiac Death, Pages 1121-1128
114 - Prevention of Stroke in Patients With Atrial Fibrillation, Pages 1129-1137
115 - Implantable Cardioverter Defibrillators: Technical Aspects, Pages 1139-1150
116 - Implantable Cardioverter Defibrillator: Clinical Aspects, Pages 1151-1165
117 - Implantable Pacemakers, Pages 1167-1177
118 - Cardiac Resynchronization Therapy, Pages 1179-1189
119 - Newer Applications of Pacemakers, Pages 1191-1197
120 - Catheter Ablation: Technical Aspects, Pages 1199-1207
121 - Catheter Ablation: Clinical Aspects, Pages 1209-1224
122 - Ablation for Atrial Fibrillation, Pages 1225-1238
123 - Ablation of Supraventricular Tachyarrhythmias, Pages 1239-1248
124 - Catheter Ablation for Ventricular Tachycardia in Patients With Structural Heart Disease, Pages 1249-1261
125 - Special Ablation Approaches: Epicardial, Other, Pages 1263-1276
126 - Ablation in Pediatrics, Pages 1277-1284
127 - Catheter Ablation in Congenital Heart Disease, Pages 1285-1294
128 - Surgery for Atrial Fibrillation and Other SVTs, Pages 1295-1305
129 - Surgery for Ventricular Arrhythmias, Pages 1307-1314.e1
130 - Vagal Stimulation for Heart Failure, Pages 1315-1320
131 - Spinal Cord Stimulation for Heart Failure and Arrhythmias, Pages 1321-1324
132 - Left Atrial Occluders/Isolation, Pages 1325-1332
Index, Pages 1333-1365