Cardiac Electrophysiology. From Cell to Bedside

Content: 
Contributors, Pages iii-xvi
Preface, Page xvii
Chapter 0 - Color Plates, Pages c1-c31
Chapter 1 - Sodium Channels, Pages 1-9
Chapter 2 - Cardiac Calcium Channels, Pages 10-18
Chapter 3 - Voltage-regulated Potassium Channels, Pages 19-32
Chapter 4 - Intracellular Signaling and Regulation of Cardiac Ion Channels, Pages 33-41
Chapter 5 - Membrane Pumps and Exchangers, Pages 42-50
Chapter 6 - Sarcoplasmic Reticulum Ion Channels, Pages 51-58
Chapter 7 - HCN Channels: From Genes to Function, Pages 59-65
Chapter 8 - Molecular Organization and Regulation of the Cardiac Gap Junction Channel Connexin43, Pages 66-76
Chapter 9 - Biophysics of Normal and Abnormal Cardiac Sodium Channel Function, Pages 77-87
Chapter 10 - Gating of Cardiac Delayed Rectifier K+ Channels, Pages 88-95
Chapter 11 - Mechanoelectric Transduction, Pages 96-102
Chapter 12 - Pacemaker Channels and Normal Automaticity, Pages 103-111
Chapter 13 - Biophysic Properties of Inward Rectifier Potassium Channels, Pages 112-119
Chapter 14 - Homomeric and Heteromeric Gap Junctions, Pages 120-126
Chapter 15 - Pharmacology of the Cardiac Sodium Channel, Pages 127-132
Chapter 16 - Pharmacology of L-Type and T-Type Calcium Channels in the Heart, Pages 133-142
Chapter 17 - KCNQ1/KCNE1 Macromolecular Signaling Complex: Channel Microdomains and Human Disease, Pages 143-149
Chapter 18 - Drug-induced Channelopathies, Pages 151-157
Chapter 19 - Prospects for Pharmacologic Targeting of Gap Junction Channels, Pages 158-167
Chapter 20 - Heterogenous Expression of Potassium Channels in the Mammalian Myocardium, Pages 169-180
Chapter 21 - Gap Junction Distribution and Regulation in the Heart, Pages 181-191
Chapter 22 - Cellular Mechanisms of Sinoatrial Activity, Pages 192-202
Chapter 23 - Mechanisms of AV Nodal Excitability and Propagation, Pages 203-212
Chapter 24 - Intercellular Communication and Impulse Propagation, Pages 213-221
Chapter 25 - Cardiac Tissue Architecture Determines Velocity and Safety of Propagation, Pages 222-231
Chapter 26 - Restitution, Repolarization, and Alternans as Arrhythmogenic Substrates, Pages 232-241
Chapter 27 - Mechanoelectric Transduction/Feedback: Prevalence and Pathophysiology, Pages 242-253
Chapter 28 - Ionic Mechanisms of Cardiac Electrical Activity: A Theoretical Approach, Pages 255-266
Chapter 29 - Two-dimensional Propagation in Cardiac Muscle, Pages 267-272
Chapter 30 - Three-dimensional Propagation in Mathematic Models: Integrative Model of the Mouse Heart, Pages 273-281
Chapter 31 - Modeling Cardiac Defibrillation, Pages 282-290
Chapter 32 - Molecular and Cellular Bases of β-Adrenergic and α-Adrenergic Modulation of Cardiac Rhythm, Pages 291-298
Chapter 33 - Nerve Sprouting and Cardiac Arrhythmias, Pages 299-305
Chapter 34 - Cholinergic Atrial Fibrillation, Pages 306-316
Chapter 35 - Theory of Reentry, Pages 317-326
Chapter 36 - Nonlinear Dynamics of Excitation and Propagation in Cardiac Muscle, Pages 327-335
Chapter 37 - Rotors and Spiral Waves in Two Dimensions, Pages 336-344
Chapter 38 - Scroll Waves in Three Dimensions, Pages 345-354
Chapter 39 - Electrophysiology of the Pulmonary Veins: Mechanisms of Initiation of Atrial Fibrillation, Pages 355-362
Chapter 40 - Mechanisms of Maintenance of Atrial Fibrillation, Pages 363-374
Chapter 41 - Electrical Remodeling and Chronic Atrial Fibrillation, Pages 375-379
Chapter 42 - Mechanisms of Initiation of Ventricular Tachyarrhythmias, Pages 380-389
Chapter 43 - Dynamics and Molecular Mechanisms of Ventricular Fibrillation in Normal Hearts, Pages 390-398
Chapter 44 - Mechanisms of Ischemic Ventricular Fibrillation: Who's the Killer?, Pages 399-406
Chapter 45 - Cellular Mechanisms of Defibrillation, Pages 407-416
Chapter 46 - Global Mechanisms Of Defibrillation, Pages 417-425
Chapter 47 - Defibrillation Waveforms, Pages 426-432
Chapter 48 - Mouse Models of Cardiac Arrhythmias, Pages 433-443
Chapter 49 - Human Molecular Genetics and the Heart, Pages 444-461
Chapter 50 - Genetics of Long QT, Brugada, and Other Channelopathies, Pages 462-470
Chapter 51 - Pharmacogenomics of Cardiac Arrhythmias and Impact on Drug Therapy, Pages 471-477
Chapter 52 - Sinus Rhythm Abnormalities, Pages 479-484
Chapter 53 - Atrioventricular Block and Atrioventricular Dissociation, Pages 485-489
Chapter 54 - Atrial Flutter: Mechanisms, Clinical Features, and Management, Pages 490-499
Chapter 55 - Atrial Tachycardia, Pages 500-511
Chapter 56 - Atrial Fibrillation, Pages 512-522
Chapter 57 - Junctional Rhythms and Junctional Tachycardia, Pages 523-527
Chapter 58 - Atrioventricular Reentry and Variants, Pages 528-536
Chapter 59 - Electrophysiologic Characteristics of Atrioventricular Nodal Reentrant Tachycardia: Implications for the Reentrant Circuits, Pages 537-557
Chapter 60 - Atrial Arrhythmias in Congenital Heart Disease, Pages 558-568
Chapter 61 - Ventricular Tachycardia in Patients with Coronary Artery Disease, Pages 569-574
Chapter 62 - Ventricular Tachycardia in Patients with Dilated Cardiomyopathy, Pages 575-587
Chapter 63 - Ventricular Tachycardia in Arrhythmogenic Right Ventricular Cardiomyopathies, Pages 588-600
Chapter 64 - Ventricular Arrhythmias in Hypertrophic Cardiomyopathy, Pages 601-607
Chapter 65 - Ventricular Tachycardia in Patients with Hypertrophy and Heart Failure, Pages 608-617
Chapter 66 - Ventricular Tachycardia in Patients Following Surgery for Congenital Heart Disease, Pages 618-624
Chapter 67 - The Brugada Syndrome, Pages 625-632
Chapter 68 - Catecholaminergic Polymorphic Ventricular Tachycardia and Short-coupled Torsades de Pointes, Pages 633-639
Chapter 69 - Arrhythmias in Patients with Neurologic Disorders, Pages 640-650
Chapter 70 - Long QT Syndrome: Genotype-Phenotype Correlations, Pages 651-659
Chapter 71 - Long QT Syndrome: Therapeutic Considerations, Pages 660-667
Chapter 72 - Ventricular Tachycardia in Patients with Structurally Normal Hearts, Pages 668-682
Chapter 73 - Bundle Branch Reentry, Pages 683-686
Chapter 74 - Torsade de Pointes, Pages 687-699
Chapter 75 - Accelerated Idioventricular Rhythm and Bidirectional Ventricular Tachycardia, Pages 700-704
Chapter 76 - Ventricular Fibrillation, Pages 705-710
Chapter 77 - Prolonged Repolarization and Sudden Infant Death Syndrome, Pages 711-719
Chapter 78 - Sudden Cardiac Death, Pages 720-731
Chapter 79 - Electrocardiographic Manifestations of Supernormal Conduction, Concealed Conduction, and Exit Block, Pages 733-738
Chapter 80 - Parasystole, Pages 739-746
Chapter 81 - Differential Diagnosis of Wide QRS Complex Tachycardia, Pages 747-757
Chapter 82 - Assessment of the Patient with a Cardiac Arrhythmia, Pages 759-764
Chapter 83 - Exercise-induced Cardiac Arrhythmias, Pages 765-771
Chapter 84 - Use of Long-term (Holter) Electrocardiographic Recordings, Pages 772-787
Chapter 85 - The Use of Implantable Loop Recorders, Pages 788-792
Chapter 86 - High-resolution Electrocardiography, Pages 793-802
Chapter 87 - Body Surface Potential Mapping, Pages 803-811
Chapter 88 - Head-up Tilt Table Testing, Pages 812-822
Chapter 89 - Heart Rate Variability and Baroreflex Sensitivity, Pages 823-830
Chapter 90 - Monophasic Action Potential Recording, Pages 831-838
Chapter 91 - T-Wave Alternans, Pages 839-847
Chapter 92 - Neurocardiac Imaging, Pages 848-857
Chapter 93 - Mapping, Pages 858-868
Chapter 94 - Wolff-Parkinson-White Syndrome, Pages 869-878
Chapter 95 - Sinus Node Dysfunction, Pages 879-883
Chapter 96 - Syncope, Pages 884-894
Chapter 97 - Results of Clinical Trials on Atrial Fibrillation, Pages 895-900
Chapter 98 - Results of Clinical Trials of Automatic External Defibrillators and Implantable Cardioverter-Defibrillators in Patients at Risk for Sudden Death, Pages 901-909
Chapter 99 - Class I Antiarrhythmic Drugs: Quinidine, Procainamide, Disopyramide, Lidocaine, Mexiletine, Flecainide, and Propafenone, Pages 911-917
Chapter 100 - β-Blockers and Calcium Channel Blockers as Antiarrhythmic Drugs, Pages 918-931
Chapter 101 - Class III Antiarrhythmic Drugs: Amiodarone, Ibutilide, and Sotalol, Pages 932-941
Chapter 102 - Adenosine and Digoxin, Pages 942-949
Chapter 103 - Impact of Nontraditional Antiarrhythmic Drugs on Sudden Cardiac Death, Pages 950-958
Chapter 104 - New Antiarrhythmic Drugs, Pages 959-965
Chapter 105 - Transthoracic Cardioversion and Defibrillation, Pages 966-969
Chapter 106 - Implantable Cardioverter-Defibrillator: Technical Aspects, Pages 970-979
Chapter 107 - Implantable Cardioverter-Defibrillators: Clinical Aspects, Pages 980-994
Chapter 108 - Implantable Atrial Defibrillators for Atrial Fibrillation, Pages 995-999
Chapter 109 - Implantable Pacemakers, Pages 1000-1010
Chapter 110 - Newer Applications of Pacemakers, Pages 1011-1017
Chapter 111 - The Biophysics and Pathophysiology of Lesion Formation during Radiofrequency Catheter Ablation, Pages 1018-1027
Chapter 112 - Catheter Ablation of Atrial Fibrillation: Triggers and Substrate, Pages 1028-1038
Chapter 113 - Pulmonary Vein Isolation for Atrial Fibrillation, Pages 1039-1052
Chapter 114 - Catheter Ablation of Atrial Flutter, Pages 1053-1059
Chapter 115 - Catheter Ablation of Atrial Tachycardia, Pages 1060-1068
Chapter 116 - Catheter Ablation of Atrioventricular Nodal Reentrant Tachycardia, Pages 1069-1077
Chapter 117 - Catheter Ablation of Atrioventricular Reentry, Pages 1078-1086
Chapter 118 - Catheter Ablation of Ventricular Tachycardia, Pages 1087-1096
Chapter 119 - Catheter Ablation in Pediatric Patients, Pages 1097-1103
Chapter 120 - Surgery for Cardiac Arrhythmias, Pages 1104-1115
Index, Pages 1117-1144