Cardiac Electrophysiology Methods and Models

Front Matter....Pages i-xiv
Front Matter....Pages 39-39
Clinical Cardiac Electrophysiology: An Overview of Its Evolution....Pages 1-38
Front Matter....Pages 39-39
Basic Cardiac Electrophysiology: Excitable Membranes....Pages 41-51
Cardiac Action Potentials, Ion Channels, and Gap Junctions....Pages 53-72
Anatomy and Physiology of the Cardiac Conduction System....Pages 73-89
The Electrocardiogram and Clinical Cardiac Electrophysiology....Pages 91-116
Front Matter....Pages 117-117
Principles of Electrophysiological In Vitro Measurements....Pages 119-134
Cardiac Cellular Electrophysiological Modeling....Pages 135-158
Computer Modeling of Electrical Activation: From Cellular Dynamics to the Whole Heart....Pages 159-185
Detection and Measurement of Cardiac Ion Channels....Pages 187-212
Cell Culture Models and Methods....Pages 213-235
Isolated Tissue Models....Pages 237-247
Isolated Heart Models....Pages 249-260
Small Animal Models for Arrhythmia Studies....Pages 261-279
Use of Large Animal Models for Cardiac Electrophysiology Studies....Pages 281-304
Optical Mapping and Calcium Imaging....Pages 305-327
Electrophysiology of Single Cardiomyocytes: Patch Clamp and Other Recording Methods....Pages 329-348
Invasive Electroanatomical Mapping and Navigation....Pages 349-356
Cardiac Electrophysiological Imaging: Solving the Inverse Problem of Electrocardiography....Pages 357-373
Traditional Electrophysiological Mapping....Pages 375-393
Multi-channel System for Analysis of Cardiac Rhythmicity and Conductivity In Vitro....Pages 395-417
Front Matter....Pages 117-117
Cardiac CT/MRI Imaging for Electrophysiology....Pages 419-437
Front Matter....Pages 439-439
Introduction to Translational Research....Pages 441-455
Clinical Perspective: Electrophysiology in the Young and Patients with Congenital Heart Disease....Pages 457-477
Back Matter....Pages 479-491