Brain Edema VIII: Proceedings of the Eighth International Symposium, Bern, June 17–20, 1990

Front Matter....Pages I-XIII
Prof. Dr. Dr. h.c. Klaus Joachim Zülch In Memoriam....Pages 1-2
Effects of Lactacidosis on Volume and Viability of Glial Cells....Pages 3-6
Mechanisms Underlying Glutamate-induced Swelling of Astrocytes in Primary Culture....Pages 7-10
The Mechanical Filtration Coefficient (L p ) of the Cell Membrane of Cultured Glioma Cells (C 6 )....Pages 11-13
Swelling of Astroglia in vitro and the Effect of Arginine Vasopressin and Atrial Natriuretic Peptide....Pages 14-16
Brain Interstitial Composition During Acute Hyponatremia....Pages 17-18
Do the Skull and Dura Exert Influence on Brain Volume Regulation Following Hypo- and Hyperosmolar Fluid Treatment?....Pages 19-21
 In vivo Measurement of Intra- and Extracellular Space of Brain Tissue by Electrical Impedance Method....Pages 22-24
Intracellular pH Regulation of Normal Rat Brain: 31 P-MRS Study....Pages 25-27
Measurement of Canine Cerebral Oedema Using Time Domain Reflectometry....Pages 28-30
A New Mapping Study of Superoxide Free Radicals, Vascular Permeability and Energy Metabolism in Central Nervous System....Pages 31-33
Measurement of Brain Tissue Density Using Pycnometry....Pages 34-36
Experimental Studies for Use of Magnetic Resonance in Brain Water Measurements....Pages 37-38
MR Studies of Brain Oedema in the Developing Animal....Pages 39-42
Passage of DMP Across a Disrupted BBB in the Context of Antibody-mediated MR Imaging of Brain Metastases....Pages 43-45
Continuous Monitoring of Blood-Brain Barrier Opening to Cr 51 -EDTA by Microdialysis Following Probe Injury....Pages 46-48
Effects of Antineutrophil Serum (ANS) on Posttraumatic Brain Oedema in Rats....Pages 49-51
The Effect of Immunosuppression with Whole Body and Regional Irradiation on the Development of Cerebral Oedema in a Rat Model of Intracerebral Haemorrhage....Pages 52-54
Effect of Stimulation of Leukocyte Chemotaxis by fMLP on White Blood Cell Behaviour in the Microcirculation of Rat Brain....Pages 55-57
Leukotriene Production by Human Glia....Pages 58-60
The Role of Arachidonic Acid and Oxygen Radicals on Cerebromicrovascular Endothelial Permeability....Pages 61-64
Possible Mechanism of Vasogenic Brain Oedema Induced by Arachidonic Acid....Pages 65-67
Effects of the Arachidonate Lipoxygenase Inhibitor BW755C on Traumatic and Peritumoural Brain Oedema....Pages 68-70
The Contribution of Secondary Mediators to the Etiology and Pathophysiology of Brain Oedema: Studies Using a Feline Infusion Oedema Model....Pages 71-73
Comparative Effects of Direct and Indirect Hydroxyl Radical Scavengers on Traumatic Brain Oedema....Pages 74-76
The Effects of Cerebral Haemodynamics on the Progression of Cold-Induced Oedema....Pages 77-78
Cryogenic Brain Oedema: Loss of Cerebrovascular Autoregulation as a Cause of Intracranial Hypertension. Implications for Treatment....Pages 79-81
An Electron Microscopic and Electron Probe Study of the Microcirculation in Cold-induced Oedema....Pages 82-83
Accumulation of Oedema Fluid in Deep White Matter After Cerebral Cold Injury....Pages 84-86
A Microstructural Study of Oedema Resolution....Pages 87-89
Routed Protein Migration After Protein Extravasation and Water Leakage Caused by Cold Injury....Pages 90-92
Immunocytochemical Studies of Oedema Protein Clearance in the Rat....Pages 93-95
Effects of Anaesthetic Agents on Cerebral Blood Flow and Brain Oedema from a Focal Lesion in Rabbit Brain....Pages 97-99
Dose- and Time-dependent Effects of Dexamethasone on Rat Brain Following Cold-injury Oedema....Pages 100-103
The Effect of Various Steroid Treatment Regimens on Cold-induced Brain Swelling....Pages 104-106
Steroid and Hyperosmotic Diuretic Effects on the Early Phase of Experimental Vasogenic Oedema....Pages 107-109
The Ambivalent Effects of Early and Late Administration of Mannitol in Cold-induced Brain Oedema....Pages 110-112
Magnetic Resonance Study of Brain Oedema Induced by Cold Injury — Changes in Relaxation Times Before and After the Administration of Glycerol....Pages 113-115
Transient Effect of Mannitol on Cerebral Blood Flow Following Brain Injury....Pages 116-117
Effects of Atrial Natriuretic Peptide on Brain Oedema: The Change of Water, Sodium, and Potassium Contents in the Brain....Pages 118-121
 In vivo Measurement of Brain Water by MRI....Pages 123-124
 1 H-NMR Studies on Water Structures in the Rat Brain Tissues with Cerebral Tumour or Ischaemia....Pages 125-127
Magnetic Resonance Imaging and Regional Biochemical Analysis of Experimental Brain Tumours in Cats....Pages 128-130
Magnetic Resonance Studies in Human Brain Oedema Following Administration of Hyperosmotic Agents....Pages 131-133
MRI Contrast Enhancement by MnTPPS of Experimental Brain Tumours in Rats....Pages 134-136
Human Malignant Gliomas Secrete a Factor that Increases Brain Capillary Permeability: Role in Peritumoural Brain Oedema....Pages 137-139
Selective Opening of the Blood-Tumour Barrier by Intracarotid Infusion of Leukotriene C 4 ....Pages 140-141
Oxygen Free Radicals in the Genesis of Peritumoural Brain Oedema in Experimental Malignant Brain Tumours....Pages 142-144
Effect of Recombinant Human Lipocortin I on Brain Oedema in a Rat Glioma Model....Pages 145-147
Formation and Resolution of White Matter Oedema in Various Types of Brain Tumours....Pages 149-151
Fluid Flow Rates in Human Peritumoural Oedema....Pages 152-154
The Finite Element Analysis of Brain Oedema Associated with Intracranial Meningiomas....Pages 155-157
The Effect of the Aminosteroid U-78517G on Peritumoural Brain Oedema....Pages 158-159
Novel 21-aminosteroids Prevent Tumour Associated Neurological Dysfunction....Pages 160-162
Therapeutic Effects of Topical Dexamethasone on Experimental Brain Tumours and Peritumoural Brain Oedema....Pages 163-164
Evaluation of Glucose Transport in Malignant Glioma by PET....Pages 165-167
Cerebral Blood Flow and Rheologic Alterations by Hyperosmolar Therapy in Patients with Brain Oedema....Pages 168-169
Restoration of Energy Metabolism and Resolution of Oedema Following Profound Ischaemia....Pages 171-173
Selective, Delayed Increase in Transfer Constants for Cerebrovascular Permeation of Blood-Borne 3 H-Sucrose Following Forebrain Ischaemia in the Rat....Pages 174-176
Electrical Impedance, rCBF, Survival and Histology in Mongolian Gerbils with Forebrain Ischaemia....Pages 177-179
Excitatory Amino Acid Receptors, Oxido-reductive Processes and Brain Oedema Following Transient Ischaemia in Gerbils....Pages 180-182
Cellular Swelling During Cerebral Ischaemia Demonstrated by Microdialysis in vivo : Preliminary Data Indicating the Role of Excitatory Amino Acids....Pages 183-185
Role of Neuroexcitation in Development of Blood-Brain Barrier and Oedematous Changes Following Cerebral Ischaemia and Traumatic Brain Injury....Pages 186-188
Inducible Ornithine Decarboxylase Expression in Brain Subject to Vasogenic Oedema After Transient Ischaemia: Relationship to C- fos Gene Expression....Pages 189-191
Ischaemic Brain Oedema and Xanthine-Xanthine Oxidase System....Pages 192-194
The Role of Endothelial Second Messenger’s-Generating System in the Pathogenesis of Brain Oedema....Pages 195-197
Effect of Glutamate and Its Antagonist on Shift of Water from Extra- to Intracellular Space After Cerebral Ischaemia....Pages 198-200
Effect of Atrial Natriuretic Peptide on Ischaemic Brain Oedema....Pages 201-203
Suppression of Water Shift into Intracellular Space by TA-3090 (Calcium Entry Blocker) Measured with NMR....Pages 204-206
Early Detection of Ischemic Injury: Comparison of Spectroscopy, Diffusion-, T2-, and Magnetic Susceptibility-Weighted MRI in Cats....Pages 207-209
Diffusion-Weighted MR Imaging and T2-Weighted MR Imaging in Acute Cerebral Ischaemia: Comparison and Correlation with Histopathology....Pages 210-212
Blood-Brain Barrier Disruption Following CPR in Piglets....Pages 213-215
Relationship Between Cerebral Blood Flow and Blood-Brain Barrier Permeability of Sodium and Albumin in Cerebral Infarcts of Rats....Pages 216-219
Extravasation of Albumin in Ischaemic Brain Oedema....Pages 220-222
Pathophysiological Studies in the Rat Cerebral Embolization Model: Measurement of Epidural Pressure and Evaluation of Tissue pH and ATP....Pages 223-225
Determiners of Fatal Reperfusion Brain Oedema....Pages 226-229
Brain Oedema and Intracranial Pressure in Superior Sagittal Sinus Balloon Occlusion. An Experimental Study in Pigs....Pages 231-232
Early Pathomorphological Changes and Intracranial Volume-Pressure: Relations Following the Experimental Saggital Sinus Occlusion....Pages 233-235
Liposome-entrapped Superoxide Dismutase Ameliorates Infarct Volume in Focal Cerebral Ischaemia....Pages 236-238
Effects of Ebselen (PZ 51) on Ischaemic Brain Oedema After Focal Ischaemia in Cats....Pages 239-241
Post-ischaemic Treatment with the Prostacycline Analogue TTC-909 Reduces Ischaemic Brain Injury....Pages 242-244
Attenuation of Glutamate-induced Neuronal Swelling and Toxicity in Transgenic Mice Overexpressing Human CuZn-Superoxide Dismutase....Pages 245-247
Effects of Atrial Natriuretic Peptide on Ischaemic Brain Oedema Evaluated by the Proton Magnetic Resonance Method....Pages 248-250
Nimodipine Attenuates Both Ischaemia-induced Brain Oedema and Mortality in a Rat Novel Transient Middle Cerebral Artery Occlusion Model....Pages 251-253
MR Evaluation of Calcium Entry Blockers with Putative Cerebroprotective Effects in Acute Cerebral Ischaemia....Pages 254-255
Effect of Steroid Therapy on Ischaemic Brain Oedema and Blood to Brain Sodium Transport....Pages 256-258
Dexamethasone Does not Influence Infarct Size but Causes Haemorrhage in Baboons with Cerebral Infarcts....Pages 259-260
Brain Oedema in Experimental Closed Head Injury in the Rat....Pages 261-262
Development of Regional Cerebral Oedema After Lateral Fluid-Percussion Brain Injury in the Rat....Pages 263-264
Survival and Fibre Outgrowth of Neuronal Cells Transplanted into Brain Areas Associated with Interstitial Oedema....Pages 265-267
Effect of Murine Recombinant Interleukin-1 on Brain Oedema in the Rat....Pages 268-270
Early Cellular Swelling in Experimental Traumatic Brain Injury: A Phenomenon Mediated by Excitatory Amino Acids....Pages 271-273
Changes in Extracellular Glutamate Concentration After Acute Subdural Haematoma in the Rat — Evidence for an “Excitotoxic” Mechanism?....Pages 274-276
Ischaemic Brain Damage Associated with Tissue Hypermetabolism in Acute Subdural Haematoma: Reduction by a Glutamate Antagonist....Pages 277-279
Autoradiographic Patterns of Brain Interstitial Fluid Flow After Collagenase-induced Haemorrhage in Rat....Pages 280-282
Analysis of MRI and SPECT in Patients with Acute Head Injury....Pages 283-285
The Time Course of Vasogenic Oedema After Focal Human Head Injury — Evidence from SPECT Mapping of Blood Brain Barrier Defects....Pages 286-288
Intracerebral Haematoma: Aetiology and Haematoma Volume Determine the Amount and Progression of Brain Oedema....Pages 289-291
Gadolinium-DTPA Enhanced Magnetic Resonance Imaging in Human Head Injury....Pages 293-295
Blood-Brain Barrier Damage in Traumatic Brain Contusions....Pages 296-299
Large and Small “Holes” in the Brain: Reversible or Irreversible Changes in Head Injury....Pages 300-301
Hemispheric CBF-Alterations in the Time Course of Focal and Diffuse Brain Injury....Pages 302-304
Correlations Between Brain Oedema Volume on CT and CSF Dynamics in Severely Head Injured Patients....Pages 305-307
Oedema Fluid Formation Within Contused Brain Tissue as a Cause of Medically Uncontrollable Elevation of Intracranial Pressure: The Role of Surgical Therapy....Pages 308-310
Magnetic Resonance Imaging and Neurobehavioural Outcome in Traumatic Brain Injury....Pages 311-314
The Effect of Nimodipine on Outcome After Head Injury: A Prospective Randomised Control Trial....Pages 315-316
Effect of THAM on Brain Oedema in Experimental Brain Injury....Pages 317-319
A Comparative Analysis of THAM (Tris-buffer) in Traumatic Brain Oedema....Pages 320-323
A Comparison of the Cerebral and Haemodynamic Effects of Mannitol and Hypertonic Saline in an Animal Model of Brain Injury....Pages 324-325
Traumatic Brain Swelling and Operative Decompression: A Prospective Investigation....Pages 326-328
The Novel 21-aminosteroid U-74006F Attenuates Cerebral Oedema and Improves Survival After Brain Injury in the Rat....Pages 329-330
The Increase in Local Cerebral Glucose Utilization Following Fluid Percussion Brain Injury is Prevented with Kynurenic Acid and is Associated with an Increase in Calcium....Pages 331-333
Presence of Transendothelial Channels in Cerebral Endothelium in Chronic Hypertension....Pages 335-337
Blood-Brain Barrier Disruption Caused by Impairment of Cerebral Autoregulation During Chronic Cerebral Vasospasm in Primates....Pages 338-340
Effect of L-arginine on Haemoglobin-induced Inhibition of Endothelium-dependent Relaxation of Isolated Cerebral Arteries....Pages 341-343
Cerebrovascular Permeability in Acute Hypertension: Effect of Flunarizine....Pages 344-345
Glutamine Synthetase Inhibition Prevents Cerebral Oedema During Hyperammonemia....Pages 346-347
Hydrocephalic Oedema in Normal-Pressure Hydrocephalus....Pages 348-350
Local Cerebral Blood Flow and Glucose Metabolism in Hydrostatic Brain Oedema....Pages 351-353
Changes in Free Water Content and Energy Metabolism of the Brain in Experimental Hydrocephalus....Pages 354-356
Venous and Cerebrospinal Fluid Outflow in Patients with Brain Swelling and Oedema....Pages 357-361
Brain Water Accumulation in Pseudotumour Cerebri Demonstrated by MR-imaging of Brain Water Self-Diffusion....Pages 363-365
Pseudotumour Cerebri-neurosurgical Considerations....Pages 366-368
Clinical Evaluation and Long-Term Follow-up in 16 Patients with Pseudotumour Cerebri....Pages 369-371
Polyamine Accumulation and Vasogenic Oedema in the Genesis of Late Delayed Radiation Injury of the Central Nervous System (CNS)....Pages 372-374
Dynamics of Tracer Distribution in Radiation Induced Brain Oedema in Rats....Pages 375-377
Superoxide Dismutase Inhibits Brain Oedema Formation in Experimental Pneumococcal Meningitis....Pages 378-380
Perifocal Brain Oedema in Experimental Brain Abscess in Rats....Pages 381-382
Brain Oedema and Cellular Changes Induced by Acute Heat Stress in Young Rats....Pages 383-386
Automated Time-averaged Analysis of Craniospinal Compliance (Short Pulse Response)....Pages 387-390
Changes in Epidural Pulse Pressure in Brain Oedema Following Experimental Focal Ischaemia....Pages 391-393
Hemodynamic Effects of Decompressive Craniectomy in Cold Induced Brain Oedema....Pages 394-396
Blood Flow and Metabolism in Vasogenic Oedema....Pages 397-400
Effect of Mannitol on Intracranial Pressure-Volume Status and Cerebral Haemodynamics in Brain Oedema....Pages 401-403
Effect of Gammahydroxybutyrate on Intracranial Pressure, Mean Systemic Arterial Pressure and Cerebral Perfusion Pressure in Experimentally Induced Brain Oedema of the Rat....Pages 404-406
Evaluation of Oedema Spreading and Intracranial Volume Reserve Using CT Image Numerical Analysis....Pages 407-408
Quantitative Analysis of CT Visualized Periventricular and Perifocal Brain Oedema by Means of CSF Dynamics Infusion Test....Pages 409-410
VPF and Interstitial Fluid Pressure in Brain Oedema....Pages 411-413
Back Matter....Pages 415-417