Brain Disease: therapeutic strategies and repair

Book Cover......Page 1
Title......Page 4
Contents......Page 5
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .......Page 7
Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .......Page 8
The spectrum of neuroimmunologic diseases......Page 14
Heterogeneity in multiple sclerosis......Page 24
Microglia and brain macrophages......Page 34
Humoral immune response and antibody-mediated brain injury......Page 42
Antibody-mediated remyelination......Page 50
Apoptosis in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE)......Page 58
Cell migration and adhesion molecules at the blood  brain barrier in experimental autoimmune encephalomyelitis and multiple sclerosis......Page 64
Matrix metalloproteinases and their inhibitors in brain injury and repair......Page 76
Monitoring progression of multiple sclerosis: p-cresol sulfate is the dominant component of urine myelin basic protein-like material......Page 82
Immunomodulation and therapy in multiple sclerosis......Page 86
Immunogene therapy for autoimmune demyelination......Page 96
DNA vaccination for central nervous system autoimmune diseases......Page 104
Stem cell transplantation for neurological diseases: new hope for disorders of myelin?......Page 110
Viruses in neurological disease......Page 120
Chronic fatigue syndrome and systemic viral infections: current evidence and recent advances......Page 140
Bacterial meningitis......Page 150
Human prion diseases......Page 156
Neurologic manifestations of lymphoproliferative disorders......Page 164
Cerebrovascular disorders: therapeutic strategies and repair......Page 176
Vasculitis of the nervous system......Page 186
Brain vasculitis and antiphospholipid syndrome......Page 206
Neuronal protection in cerebral ischemia;from lessons of the past to a brighter future......Page 214
Immunomodulation;new therapeutic opportunities for stroke......Page 224
Toxicity of tumor necrosis factor is enhanced by reactive oxygen species after brain trauma......Page 232
Protective autoimmunity: is vaccination for neurodegenerative disorders feasible?......Page 238
The molecular biology of blood  brain barrier disruption under stress: the potential involvement of acetylcholinesterase......Page 244
Clinically important interactions involving new antiepileptic drugs......Page 252
Challenges in monitoring the new antiepileptic drugs......Page 258
Aggravation of seizures by antiepileptic drugs: pathophysiology and clinical implications......Page 264
Management of paroxysmal symptoms in multiple sclerosis......Page 270
An update on therapy for Parkinson's disease......Page 280
Restoring structure and function of the nigrostriatal system in Parkinson's disease......Page 288
Therapeutic of hyperkinetic movement disorders......Page 296
Molecular events in dopaminergic neurodegeneration and neuroprotection in MPTP model of Parkinson's disease employing cDNA microarray......Page 304
Alzheimer's disease......Page 312
Vasculitic neuropathies......Page 326
Acquired demyelinating neuropathies: molecular mechanisms and novel therapeutical approaches......Page 338
Radiation damage to peripheral nerves......Page 350
Neuropathy due to malignant hematological diseases......Page 360
Hereditary inclusion body myopathies: clinical and genetic features......Page 364
Exercise testing in muscle disease......Page 370
Disorders of emotional behaviour......Page 382
Cognitive and affective disturbances in multiple sclerosis......Page 388
From spinal shock to spasticity......Page 392
Pathophysiology and treatment of fatigue in multiple sclerosis......Page 402
Management of vertigo and vestibular disorders......Page 408
Eye movements: supranuclear mechanisms and their disorders......Page 418
The role of radionucleid brain scan and multimodality......Page 432
Imaging brain inflammation......Page 438
Advances in neurosonology......Page 448
Neurophysiology of inflammatory demyelinating disease......Page 460
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .......Page 476