Biological Basis of Detoxication

Content: 
BIOCHEMICAL PHARMACOLOGY AND TOXICOLOGY: A Series of Monographs, Page ii
Front Matter, Page iii
Copyright, Page iv
Contributors, Pages xi-xii
Preface, Page xiii, John Caldwell, William B. Jakoby
CHAPTER 1 - Metabolic Formation of Toxic Metabolites, Pages 1-30, Scott W. Cummings, Russell A. Prough
CHAPTER 2 - Integration of Xenobiotic Metabolism in Carcinogen Activation and Detoxication, Pages 31-76, Colin R. Jefcoate
CHAPTER 3 - Ontogenesis, Pages 77-103, Julian E.A. Leakey
CHAPTER 4 - Intratissue Distribution of Activating and Detoxicating Enzymes, Pages 105-135, Jeffrey Baron, Thomas T. Kawabata
CHAPTER 5 - Nonenzymatic Biotransformation, Pages 137-150, Bernard Testa
CHAPTER 6 - Unmetabolized Compounds, Pages 151-179, A.G. Renwick
CHAPTER 7 - Biological Basis of Detoxication of Oxygen Free Radicals, Pages 181-211, Helmut Sies, Enrique Cadenas
CHAPTER 8 - Fate of Xenobiotics: Physiologic and Kinetic Considerations, Pages 213-250, K. Sandy Pang
CHAPTER 9 - Excretion Mechanisms, Pages 251-285, Walter G. Levine
CHAPTER 10 - Impact of Nutrition on Detoxication, Pages 287-306, Juanell N. Boyd, T. Colin Campbell
CHAPTER 11 - Relationships between the Enzymes of Detoxication and Host Defense Mechanisms, Pages 307-324, Kenneth W. Renton
CHAPTER 12 - Metabolic Basis of Target Organ Toxicity, Pages 325-347, Gerald M. Cohen
CHAPTER 13 - Enzymes in Selective Toxicity, Pages 349-368, C.H. Walker, F. Oesch
CHAPTER 14 - Intraindividual and Interindividual Variations, Pages 369-410, Elliot S. Vesell, M.B. Penno
Index, Pages 411-429