Bioinorganic Chemistry: An Inorganic Perspective of Life

Front Matter....Pages i-xx
Front Matter....Pages xxi-xxi
Methane Monooxygenase....Pages 1-12
The Coordination Chemistry of Iron in Biological Transport and Storage; Iron Removal in Vivo ....Pages 13-24
Siderophore-Mediated Iron Transport in Microbes....Pages 25-37
On the Mechanism of Epoxidation and Hydroxylation Catalyzed by Iron Porphyrins. Evidence for Non-Intersecting Reaction Pathways....Pages 39-47
Self-Assembly, Catalysis and Electron Transfer with Metalloporphyrins in Phospholipid Membranes....Pages 49-56
Mechanistic Studies on the Binuclear Fe Enzymes Ribonucleotide Reductase and Purple Acid Phosphatase....Pages 57-65
Structure and Reactivity of the Blue Copper Proteins....Pages 67-76
Copper-Zinc Superoxide Dismutase: Mechanistic and Biological Studies....Pages 77-91
NMR of Paramagnetic Molecules: A Contribution to the Understanding of Enzymatic Mechanisms....Pages 93-104
Magnetic and EPR Studies of Superoxide Dismutases (SOD): Electronic Structure of the Active Sites for the (Copper-Zinc)SOD, its Cobalt Substituted Derivative and the Iron(III)SOD from E. Coli ....Pages 105-111
Mechanism of Action of Thiamin Enzymes Role of Metal Ions....Pages 113-128
Front Matter....Pages 129-129
Platinum Anticancer Drugs....Pages 131-140
NMR Spectroscopic Structure Determination of Metal Ion — Oligonucleotide Complexes — The Results of Sequence-Selective Binding Studies....Pages 141-153
Metal Ion-Coordinating Properties in Solution of Purine-Nucleoside 5’-Monophosphates and Some Analogues....Pages 155-178
Metal-Nucleobase Chemistry: Coordination, Reactivity, and Base Pairing....Pages 179-199
DNA Cleavage by Cationic Metalloporphyrins....Pages 201-208
The Role of Metal Ions in Biological Systems and Medicine....Pages 209-218
The Interaction of Heavy Metal Ions with DNA....Pages 219-235
Thermodynamics and Kinetics of Competing Redox Processes During DNA Cleavage: Reactivity-Based Selectivity....Pages 237-243
Front Matter....Pages 245-245
Mo/S Chemistry and Its Importance in Enzymatic Catalysis....Pages 247-274
Front Matter....Pages 245-245
Use of De Novo Designed Peptides for the Study of Metalloproteins and Enzymes....Pages 275-285
Modeling the Chemistry and Properties of Multinuclear Manganese Enzymes....Pages 287-298
Manganese-Proteins and -Enzymes and Relevant Trinuclear Synthetic Complexes....Pages 299-320
Catalytic Oxidation of Pollutants by Ligninase Models Based on Metalloporphyrins and Metallophthalocyanines....Pages 321-331
Nickel Coordination Chemistry with Oxothiolate Ligands and Its Relevance to Hydrogenase Enzymes....Pages 333-348
Artificial Batteries with Lanthanide Porphyrins?....Pages 349-357
Novel Transition Metal Heteropolymetalates and Derivatives: Structural Chemistry, Biological and Catalytic Relevance....Pages 359-370
Purple Acid Phosphatases and Catechol Oxidase and their Model Compounds. Crystal Structure Studies of Purple Acid Phosphatase from Red Kidney Beans....Pages 371-384
Molybdenum — Copper Antagonism....Pages 385-400
Back Matter....Pages 401-415