Biochemical Engineering

Preface
Chapter 1 Introduction
Importance of bioprocessing and scale-up in new biotechnology.
Chapter 2 Enzyme Kinetics
Simple enzyme kinetics, enzyme reactor, inhibition, other
influences, and experiments
Chapter 3 Immobilized Enzymes
Immobilization techniques and effect of mass transfer resistance
Chapter 4 Industrial Applications of Enzymes
Carbohydrates, starch conversion, cellulose conversion, and
experiments
Chapter 5 Cell Cultivations
Microbial, animal, and plant cell cultivations, cell growth
measurement, cell immobilization, and experiments
Chapter 6 Cell Kinetics and Fermenter Design
Growth cycle, cell kinetics, batch or plug-flow stirred-tank
fermenter, continuous stirred-tank fermenter (CSTF), multiple
fermenters in series, CSTF with cell recycling, alternative
fermenters, and structured kinetic models
Chapter 7 Genetic Engineering
DNA and RNA, cloning of genes, stability of recombinant cells,
and genetic engineering of plant cells
Chapter 8 Sterilization
Sterilization methods, thermal death kinetics, design criterion,
batch and continuous sterilization, and air sterilization
Chapter 9 Agitation and Aeration
Basic mass-transfer concepts, correlations form mass-transfer
coefficient, measurement of interfacial area, correlations for
interfacial area, gas hold-up, power consumption, oxygen
absorption rate, scale-up, and shear sensitive mixing
Chapter 10 Downstream Processing
Solid-liquid separation, cell rupture, recovery, and purification